Organization pitching register - 2008
Regular season
| Primary |
| Name | Team | P | Age | ERA | W | L | S | G | GS | CG | SHO | INN | H | R | ER | BB | K | HR | GDP |
| Jeremy Accardo | CHI | cl | 26 | 5.17 | 2 | 1 | 0 | 48 | 0 | 0 | 0 | 54.0 | 63 | 32 | 31 | 24 | 46 | 8 | 1 |
| Jeremy Affeldt* | CWS | mr | 29 | 5.08 | 3 | 0 | 0 | 42 | 0 | 0 | 0 | 51.1 | 44 | 30 | 29 | 37 | 48 | 3 | 11 |
| Bronson Arroyo | SFG | sp | 31 | 6.28 | 8 | 13 | 0 | 31 | 31 | 0 | 0 | 176.1 | 229 | 137 | 123 | 50 | 141 | 25 | 10 |
| Luis Ayala | CWS | mr | 30 | 4.74 | 0 | 3 | 1 | 15 | 0 | 0 | 0 | 19.0 | 19 | 10 | 10 | 13 | 12 | 4 | 2 |
| Cha Seung Baek | NYM | sp | 28 | 7.09 | 1 | 8 | 0 | 24 | 10 | 0 | 0 | 66.0 | 99 | 58 | 52 | 17 | 44 | 4 | 1 |
| Homer Bailey | HOU | sp | 22 | 5.28 | 0 | 3 | 4 | 35 | 0 | 0 | 0 | 44.1 | 48 | 32 | 26 | 28 | 20 | 2 | 12 |
| Scott Baker | MIL | sp | 26 | 6.05 | 6 | 9 | 0 | 30 | 16 | 0 | 0 | 116.0 | 158 | 92 | 78 | 26 | 75 | 25 | 16 |
| John Bale* | SFG | mr | 34 | 1.05 | 2 | 0 | 0 | 16 | 0 | 0 | 0 | 25.2 | 23 | 3 | 3 | 3 | 33 | 1 | 1 |
| Brian Bannister | HOU | sp | 27 | 4.11 | 6 | 6 | 1 | 41 | 20 | 0 | 0 | 157.2 | 159 | 82 | 72 | 45 | 67 | 11 | 14 |
| Miguel Batista | PIT | sp | 37 | 2.78 | 4 | 2 | 2 | 29 | 6 | 0 | 0 | 77.2 | 76 | 27 | 24 | 32 | 64 | 6 | 6 |
| Josh Beckett | WAS | sp | 28 | 3.68 | 7 | 15 | 0 | 31 | 30 | 3 | 2 | 191.0 | 177 | 91 | 78 | 54 | 191 | 21 | 10 |
| Erik Bedard* | HOU | sp | 29 | 3.30 | 6 | 4 | 0 | 15 | 14 | 0 | 0 | 95.1 | 84 | 39 | 35 | 33 | 108 | 10 | 8 |
| Erik Bedard* | STL | sp | 29 | 4.25 | 7 | 3 | 0 | 14 | 14 | 0 | 0 | 78.1 | 80 | 38 | 37 | 24 | 97 | 15 | 3 |
| Erik Bedard* |   | sp | 29 | 3.73 | 13 | 7 | 0 | 29 | 28 | 0 | 0 | 173.2 | 164 | 77 | 72 | 57 | 205 | 25 | 11 |
| Joe Beimel* | MIN | mr | 31 | 2.51 | 4 | 2 | 7 | 59 | 0 | 0 | 0 | 64.2 | 59 | 20 | 18 | 24 | 47 | 2 | 9 |
| Matt Belisle | SFG | sp | 28 | 6.87 | 3 | 3 | 0 | 10 | 10 | 0 | 0 | 55.0 | 78 | 44 | 42 | 13 | 37 | 14 | 5 |
| Heath Bell | KCA | mr | 30 | 2.55 | 10 | 3 | 8 | 65 | 0 | 0 | 0 | 81.1 | 57 | 23 | 23 | 32 | 86 | 6 | 8 |
| Joaquin Benoit | SFG | mr | 30 | 4.42 | 3 | 6 | 0 | 54 | 0 | 0 | 0 | 75.1 | 78 | 40 | 37 | 28 | 79 | 13 | 5 |
| Jason Bergmann | SFG | sp | 26 | 6.37 | 3 | 2 | 0 | 6 | 6 | 0 | 0 | 35.1 | 41 | 26 | 25 | 23 | 30 | 5 | 3 |
| Jason Bergmann | WAS | sp | 26 | 6.50 | 0 | 8 | 0 | 9 | 9 | 0 | 0 | 54.0 | 56 | 42 | 39 | 30 | 56 | 18 | 4 |
| Jason Bergmann |   | sp | 26 | 6.45 | 3 | 10 | 0 | 15 | 15 | 0 | 0 | 89.1 | 97 | 68 | 64 | 53 | 86 | 23 | 7 |
| Rafael Betancourt | BOS | mr | 33 | 2.70 | 1 | 3 | 6 | 27 | 0 | 0 | 0 | 33.1 | 28 | 10 | 10 | 6 | 35 | 3 | 0 |
| Rafael Betancourt | MIN | mr | 33 | 3.43 | 2 | 2 | 2 | 32 | 0 | 0 | 0 | 39.1 | 32 | 15 | 15 | 3 | 45 | 4 | 0 |
| Rafael Betancourt |   | mr | 33 | 3.10 | 3 | 5 | 8 | 59 | 0 | 0 | 0 | 72.2 | 60 | 25 | 25 | 9 | 80 | 7 | 0 |
| Chad Billingsley | CLE | mr | 23 | 3.97 | 7 | 2 | 2 | 67 | 9 | 1 | 0 | 136.0 | 120 | 64 | 60 | 67 | 113 | 15 | 10 |
| Joe Blanton | DET | sp | 27 | 5.56 | 8 | 12 | 0 | 30 | 30 | 0 | 0 | 173.1 | 223 | 113 | 107 | 46 | 112 | 28 | 17 |
| Jeremy Bonderman | DET | sp | 25 | 4.21 | 12 | 6 | 0 | 26 | 26 | 0 | 0 | 147.1 | 162 | 74 | 69 | 41 | 137 | 19 | 17 |
| Boof Bonser | CIN | sp | 26 | 6.06 | 5 | 15 | 0 | 33 | 32 | 0 | 0 | 170.2 | 198 | 134 | 115 | 57 | 143 | 42 | 15 |
| Dave Borkowski | BOS | mr | 31 | 3.38 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 8.0 | 8 | 3 | 3 | 4 | 3 | 2 | 1 |
| Joe Borowski | BAL | cl | 37 | 5.79 | 0 | 4 | 1 | 42 | 0 | 0 | 0 | 51.1 | 61 | 36 | 33 | 9 | 59 | 11 | 3 |
| Micah Bowie* | CWS | mr | 33 | 2.25 | 3 | 1 | 0 | 9 | 5 | 0 | 0 | 36.0 | 29 | 9 | 9 | 6 | 38 | 2 | 3 |
| Dallas Braden* | WAS | sp | 24 | 6.44 | 3 | 3 | 1 | 41 | 3 | 0 | 0 | 64.1 | 90 | 46 | 46 | 27 | 52 | 14 | 1 |
| Chad Bradford | BAL | mr | 33 | 5.94 | 1 | 1 | 1 | 41 | 0 | 0 | 0 | 50.0 | 66 | 37 | 33 | 10 | 20 | 6 | 7 |
| Doug Brocail | PIT | mr | 41 | 4.33 | 6 | 3 | 1 | 53 | 0 | 0 | 0 | 72.2 | 75 | 40 | 35 | 26 | 34 | 9 | 8 |
| Andrew Brown | LAD | mr | 27 | 3.83 | 2 | 2 | 5 | 29 | 1 | 0 | 0 | 42.1 | 43 | 22 | 18 | 14 | 40 | 2 | 5 |
| Jonathan Broxton | KCA | mr | 24 | 3.34 | 2 | 2 | 1 | 47 | 0 | 0 | 0 | 67.1 | 63 | 28 | 25 | 16 | 77 | 5 | 7 |
| Brian Bruney | WAS | mr | 26 | 10.90 | 0 | 4 | 2 | 27 | 0 | 0 | 0 | 34.2 | 50 | 45 | 42 | 32 | 30 | 8 | 4 |
| Taylor Buchholz | BAL | mr | 26 | 3.77 | 1 | 3 | 1 | 41 | 0 | 0 | 0 | 76.1 | 92 | 38 | 32 | 16 | 51 | 3 | 13 |
| Mark Buehrle* | CIN | sp | 29 | 3.67 | 4 | 3 | 0 | 15 | 13 | 2 | 1 | 88.1 | 85 | 44 | 36 | 30 | 51 | 9 | 6 |
| Mark Buehrle* | CLE | sp | 29 | 3.69 | 4 | 7 | 0 | 16 | 16 | 0 | 0 | 105.0 | 109 | 51 | 43 | 26 | 81 | 14 | 9 |
| Mark Buehrle* |   | sp | 29 | 3.68 | 8 | 10 | 0 | 31 | 29 | 2 | 1 | 193.1 | 194 | 95 | 79 | 56 | 132 | 23 | 15 |
| Ambiorix Burgos | MIL | mr | 24 | 1.86 | 3 | 0 | 0 | 22 | 0 | 0 | 0 | 29.0 | 14 | 7 | 6 | 11 | 29 | 3 | 0 |
| A.J. Burnett | MIL | sp | 31 | 4.15 | 8 | 4 | 0 | 13 | 11 | 2 | 1 | 86.2 | 77 | 44 | 40 | 16 | 91 | 11 | 11 |
| A.J. Burnett | NYA | sp | 31 | 4.89 | 4 | 3 | 0 | 13 | 12 | 0 | 0 | 77.1 | 72 | 47 | 42 | 33 | 66 | 7 | 11 |
| A.J. Burnett |   | sp | 31 | 4.50 | 12 | 7 | 0 | 26 | 23 | 2 | 1 | 164.0 | 149 | 91 | 82 | 49 | 157 | 18 | 22 |
| Brian Burres* | WAS | mr | 27 | 6.59 | 0 | 2 | 0 | 14 | 0 | 0 | 0 | 27.1 | 35 | 25 | 20 | 19 | 24 | 3 | 3 |
| Jared Burton | NYA | mr | 27 | 3.18 | 4 | 2 | 2 | 42 | 0 | 0 | 0 | 39.2 | 27 | 17 | 14 | 22 | 31 | 2 | 6 |
| Dave Bush | CIN | sp | 28 | 5.89 | 5 | 15 | 0 | 30 | 30 | 2 | 0 | 165.0 | 214 | 119 | 108 | 52 | 111 | 27 | 11 |
| Paul Byrd | NYM | sp | 37 | 4.67 | 2 | 3 | 0 | 15 | 14 | 0 | 0 | 88.2 | 105 | 49 | 46 | 14 | 47 | 14 | 7 |
| Tim Byrdak* | PIT | mr | 34 | 3.20 | 1 | 0 | 4 | 45 | 0 | 0 | 0 | 45.0 | 41 | 18 | 16 | 25 | 47 | 2 | 2 |
| Daniel Cabrera | WAS | sp | 27 | 4.98 | 7 | 17 | 0 | 30 | 29 | 5 | 0 | 200.2 | 215 | 125 | 111 | 115 | 167 | 24 | 19 |
| Matt Cain | LAD | sp | 23 | 3.62 | 6 | 4 | 0 | 18 | 18 | 0 | 0 | 114.1 | 95 | 52 | 46 | 55 | 99 | 14 | 3 |
| Matt Cain | CAL | sp | 23 | 6.84 | 2 | 8 | 0 | 12 | 12 | 0 | 0 | 73.2 | 88 | 60 | 56 | 38 | 60 | 8 | 4 |
| Matt Cain |   | sp | 23 | 4.88 | 8 | 12 | 0 | 30 | 30 | 0 | 0 | 188.0 | 183 | 112 | 102 | 93 | 159 | 22 | 7 |
| Kevin Cameron | CAL | mr | 28 | 4.33 | 1 | 0 | 0 | 37 | 0 | 0 | 0 | 52.0 | 52 | 30 | 25 | 40 | 46 | 2 | 8 |
| Matt Capps | CWS | mr | 24 | 1.64 | 3 | 0 | 9 | 63 | 0 | 0 | 0 | 77.0 | 56 | 14 | 14 | 11 | 55 | 3 | 7 |
| Chris Capuano* | BAL | sp | 29 | 7.38 | 5 | 13 | 0 | 28 | 27 | 0 | 0 | 135.1 | 175 | 115 | 111 | 75 | 127 | 32 | 17 |
| Fausto Carmona | PIT | sp | 24 | 2.65 | 21 | 7 | 0 | 33 | 33 | 0 | 0 | 221.0 | 187 | 75 | 65 | 47 | 160 | 13 | 28 |
| Chris Carpenter | MIN | sp | 33 | 10.38 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 4.1 | 4 | 6 | 5 | 5 | 0 | 1 | 0 |
| Santiago Casilla | STL | mr | 27 | 3.83 | 4 | 1 | 0 | 44 | 0 | 0 | 0 | 51.2 | 34 | 22 | 22 | 14 | 55 | 11 | 1 |
| Gustavo Chacin* | CHI | sp | 27 | 11.81 | 0 | 1 | 0 | 3 | 3 | 0 | 0 | 10.2 | 26 | 15 | 14 | 5 | 8 | 7 | 0 |
| Shawn Chacon | NYM | mr | 30 | 6.50 | 2 | 5 | 5 | 62 | 0 | 0 | 0 | 88.2 | 108 | 69 | 64 | 41 | 63 | 11 | 6 |
| Matt Chico* | BOS | sp | 25 | 6.65 | 3 | 4 | 0 | 12 | 12 | 1 | 0 | 69.0 | 83 | 55 | 51 | 36 | 44 | 12 | 5 |
| Vinnie Chulk | DET | mr | 29 | 2.57 | 1 | 1 | 0 | 31 | 0 | 0 | 0 | 42.0 | 41 | 14 | 12 | 12 | 32 | 5 | 4 |
| Roger Clemens | NYA | sp | 45 | 4.35 | 3 | 3 | 0 | 11 | 11 | 1 | 1 | 62.0 | 76 | 35 | 30 | 15 | 48 | 8 | 2 |
| Jesus Colome | CLE | mr | 30 | 5.52 | 2 | 4 | 3 | 62 | 0 | 0 | 0 | 58.2 | 74 | 39 | 36 | 30 | 39 | 2 | 6 |
| Jose Contreras | MIL | sp | 36 | 4.09 | 0 | 3 | 1 | 28 | 5 | 0 | 0 | 70.1 | 77 | 44 | 32 | 13 | 43 | 10 | 7 |
| Jose Contreras | CIN | sp | 36 | 6.10 | 6 | 3 | 0 | 18 | 18 | 0 | 0 | 97.1 | 124 | 69 | 66 | 27 | 47 | 18 | 10 |
| Jose Contreras |   | sp | 36 | 5.26 | 6 | 6 | 1 | 46 | 23 | 0 | 0 | 167.2 | 201 | 113 | 98 | 40 | 90 | 28 | 17 |
| Aaron Cook | MIN | sp | 29 | 4.46 | 7 | 5 | 1 | 34 | 21 | 1 | 1 | 153.1 | 186 | 81 | 76 | 36 | 69 | 10 | 21 |
| Chad Cordero | CLE | cl | 26 | 2.21 | 4 | 2 | 17 | 42 | 0 | 0 | 0 | 36.2 | 45 | 10 | 9 | 17 | 26 | 0 | 4 |
| Chad Cordero | DET | cl | 26 | 5.00 | 2 | 2 | 1 | 27 | 0 | 0 | 0 | 27.0 | 34 | 18 | 15 | 12 | 26 | 2 | 4 |
| Chad Cordero |   | cl | 26 | 3.39 | 6 | 4 | 18 | 69 | 0 | 0 | 0 | 63.2 | 79 | 28 | 24 | 29 | 52 | 2 | 8 |
| Francisco Cordero | NYA | cl | 33 | 4.27 | 1 | 3 | 2 | 64 | 0 | 0 | 0 | 52.2 | 49 | 26 | 25 | 24 | 66 | 4 | 5 |
| Manny Corpas | PIT | mr | 25 | 2.27 | 1 | 1 | 4 | 36 | 0 | 0 | 0 | 43.2 | 36 | 12 | 11 | 19 | 23 | 2 | 6 |
| Kevin Correia | LAD | mr | 27 | 3.15 | 8 | 6 | 0 | 23 | 15 | 0 | 0 | 105.2 | 89 | 40 | 37 | 38 | 87 | 6 | 7 |
| Neal Cotts* | CLE | mr | 28 | 4.24 | 0 | 0 | 0 | 21 | 0 | 0 | 0 | 17.0 | 15 | 8 | 8 | 10 | 16 | 1 | 4 |
| Juan Cruz | NYM | mr | 29 | 2.80 | 4 | 1 | 2 | 44 | 0 | 0 | 0 | 61.0 | 42 | 20 | 19 | 40 | 90 | 4 | 1 |
| John Danks* | BOS | sp | 23 | 5.89 | 2 | 10 | 0 | 21 | 19 | 0 | 0 | 107.0 | 121 | 74 | 70 | 34 | 98 | 27 | 8 |
| Kyle Davies | WAS | sp | 24 | 7.86 | 1 | 11 | 0 | 25 | 18 | 1 | 0 | 126.0 | 157 | 120 | 110 | 77 | 89 | 31 | 7 |
| Doug Davis* | MIL | sp | 32 | 5.82 | 3 | 15 | 0 | 35 | 28 | 0 | 0 | 162.1 | 218 | 112 | 105 | 84 | 124 | 18 | 13 |
| Jorge De La Rosa* | NYM | sp | 27 | 3.38 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 8.0 | 8 | 3 | 3 | 0 | 3 | 1 | 1 |
| Manny Delcarmen | KCA | mr | 26 | 2.93 | 2 | 0 | 1 | 32 | 0 | 0 | 0 | 43.0 | 24 | 14 | 14 | 24 | 38 | 8 | 3 |
| Ryan Dempster | BAL | cl | 31 | 5.70 | 1 | 5 | 9 | 49 | 0 | 0 | 0 | 53.2 | 54 | 36 | 34 | 28 | 48 | 8 | 4 |
| Lenny DiNardo* | NYM | sp | 28 | 5.02 | 7 | 10 | 2 | 49 | 12 | 0 | 0 | 120.0 | 160 | 75 | 67 | 42 | 69 | 14 | 24 |
| Brendan Donnelly | BOS | mr | 36 | 7.04 | 1 | 0 | 0 | 14 | 0 | 0 | 0 | 15.1 | 17 | 13 | 12 | 5 | 11 | 0 | 0 |
| Scott Downs* | NYM | mr | 32 | 5.74 | 4 | 6 | 11 | 45 | 0 | 0 | 0 | 47.0 | 62 | 36 | 30 | 22 | 48 | 5 | 0 |
| Brandon Duckworth | CLE | mr | 32 | 3.86 | 1 | 1 | 1 | 12 | 0 | 0 | 0 | 11.2 | 5 | 5 | 5 | 9 | 3 | 0 | 3 |
| Zach Duke* | CHI | sp | 25 | 11.45 | 1 | 2 | 0 | 50 | 0 | 0 | 0 | 74.2 | 143 | 95 | 95 | 21 | 32 | 21 | 15 |
| Chad Durbin | NYM | sp | 30 | 5.64 | 7 | 7 | 0 | 29 | 19 | 0 | 0 | 126.0 | 145 | 83 | 79 | 32 | 64 | 21 | 9 |
| J.D. Durbin | WAS | sp | 26 | 4.71 | 1 | 5 | 1 | 38 | 2 | 0 | 0 | 65.0 | 65 | 35 | 34 | 25 | 49 | 5 | 9 |
| Alan Embree* | BOS | cl | 38 | 3.57 | 2 | 4 | 3 | 43 | 0 | 0 | 0 | 40.1 | 44 | 17 | 16 | 9 | 30 | 3 | 3 |
| Alan Embree* | MIN | cl | 38 | 3.71 | 2 | 0 | 0 | 23 | 0 | 0 | 0 | 26.2 | 28 | 11 | 11 | 6 | 14 | 2 | 4 |
| Alan Embree* |   | cl | 38 | 3.63 | 4 | 4 | 3 | 66 | 0 | 0 | 0 | 67.0 | 72 | 28 | 27 | 15 | 44 | 5 | 7 |
| Kelvim Escobar | NYA | sp | 32 | 3.58 | 9 | 5 | 0 | 32 | 31 | 1 | 1 | 196.0 | 178 | 86 | 78 | 63 | 166 | 17 | 22 |
| Kyle Farnsworth | CLE | mr | 32 | 4.17 | 2 | 3 | 5 | 52 | 0 | 0 | 0 | 58.1 | 45 | 32 | 27 | 27 | 49 | 11 | 1 |
| Pedro Feliciano* | STL | mr | 31 | 3.20 | 3 | 3 | 2 | 61 | 0 | 0 | 0 | 59.0 | 47 | 22 | 21 | 36 | 54 | 8 | 6 |
| Josh Fogg | SFG | sp | 31 | 7.65 | 3 | 5 | 0 | 11 | 11 | 0 | 0 | 57.2 | 91 | 49 | 49 | 19 | 37 | 7 | 6 |
| Jeff Francis* | DET | sp | 27 | 4.21 | 9 | 7 | 0 | 30 | 30 | 0 | 0 | 181.2 | 195 | 92 | 85 | 61 | 153 | 22 | 20 |
| Frank Francisco | PHI | mr | 28 | 5.80 | 4 | 3 | 0 | 37 | 0 | 0 | 0 | 45.0 | 52 | 32 | 29 | 25 | 44 | 5 | 4 |
| Ryan Franklin | CWS | mr | 35 | 3.44 | 4 | 2 | 2 | 50 | 0 | 0 | 0 | 73.1 | 70 | 29 | 28 | 21 | 48 | 8 | 5 |
| Jason Frasor | SFG | mr | 30 | 6.00 | 0 | 0 | 0 | 33 | 0 | 0 | 0 | 45.0 | 53 | 31 | 30 | 22 | 48 | 5 | 1 |
| Brian Fuentes* | LAD | cl | 32 | 5.14 | 0 | 2 | 4 | 15 | 0 | 0 | 0 | 14.0 | 17 | 8 | 8 | 13 | 13 | 1 | 0 |
| Brian Fuentes* | NYA | cl | 32 | 4.46 | 5 | 4 | 0 | 57 | 0 | 0 | 0 | 40.1 | 27 | 22 | 20 | 31 | 49 | 2 | 2 |
| Brian Fuentes* |   | cl | 32 | 4.64 | 5 | 6 | 4 | 72 | 0 | 0 | 0 | 54.1 | 44 | 30 | 28 | 44 | 62 | 3 | 2 |
| Aaron Fultz* | CAL | mr | 34 | 4.02 | 3 | 3 | 0 | 43 | 0 | 0 | 0 | 31.1 | 31 | 14 | 14 | 23 | 30 | 4 | 2 |
| Kason Gabbard* | CAL | sp | 26 | 3.78 | 4 | 2 | 0 | 12 | 12 | 0 | 0 | 78.2 | 67 | 33 | 33 | 38 | 62 | 9 | 9 |
| Eric Gagne | MIL | cl | 32 | 4.76 | 3 | 1 | 6 | 25 | 0 | 0 | 0 | 34.0 | 27 | 18 | 18 | 23 | 33 | 1 | 2 |
| Eric Gagne | BOS | cl | 32 | 7.04 | 0 | 1 | 0 | 13 | 0 | 0 | 0 | 15.1 | 22 | 13 | 12 | 14 | 12 | 3 | 2 |
| Eric Gagne |   | cl | 32 | 5.47 | 3 | 2 | 6 | 38 | 0 | 0 | 0 | 49.1 | 49 | 31 | 30 | 37 | 45 | 4 | 4 |
| Yovani Gallardo | MIL | sp | 22 | 5.92 | 2 | 5 | 0 | 9 | 9 | 0 | 0 | 51.2 | 69 | 38 | 34 | 21 | 46 | 5 | 6 |
| Yovani Gallardo | PIT | sp | 22 | 5.47 | 0 | 3 | 0 | 4 | 4 | 0 | 0 | 24.2 | 30 | 15 | 15 | 15 | 21 | 2 | 0 |
| Yovani Gallardo |   | sp | 22 | 5.78 | 2 | 8 | 0 | 13 | 13 | 0 | 0 | 76.1 | 99 | 53 | 49 | 36 | 67 | 7 | 6 |
| Lee Gardner | PIT | mr | 33 | 2.05 | 7 | 1 | 4 | 61 | 0 | 0 | 0 | 70.1 | 74 | 19 | 16 | 21 | 50 | 2 | 7 |
| Jon Garland | KCA | sp | 28 | 4.01 | 16 | 6 | 0 | 28 | 28 | 0 | 0 | 186.1 | 193 | 84 | 83 | 52 | 108 | 18 | 24 |
| Matt Garza | CAL | sp | 24 | 3.84 | 5 | 4 | 0 | 12 | 12 | 1 | 0 | 77.1 | 86 | 35 | 33 | 33 | 91 | 6 | 11 |
| Chad Gaudin | CIN | sp | 25 | 6.57 | 1 | 7 | 0 | 16 | 15 | 0 | 0 | 76.2 | 100 | 59 | 56 | 33 | 62 | 16 | 5 |
| Chad Gaudin | STL | sp | 25 | 5.75 | 3 | 6 | 0 | 15 | 13 | 0 | 0 | 81.1 | 95 | 57 | 52 | 26 | 70 | 17 | 5 |
| Chad Gaudin |   | sp | 25 | 6.15 | 4 | 13 | 0 | 31 | 28 | 0 | 0 | 158.0 | 195 | 116 | 108 | 59 | 132 | 33 | 10 |
| Geoff Geary | BOS | mr | 31 | 5.40 | 3 | 0 | 2 | 21 | 0 | 0 | 0 | 26.2 | 28 | 18 | 16 | 8 | 16 | 6 | 5 |
| Justin Germano | CAL | sp | 25 | 4.82 | 3 | 11 | 0 | 19 | 19 | 2 | 0 | 121.1 | 160 | 74 | 65 | 40 | 95 | 16 | 14 |
| Tom Glavine* | LAD | sp | 42 | 4.17 | 14 | 10 | 0 | 32 | 32 | 0 | 0 | 192.0 | 236 | 93 | 89 | 63 | 80 | 19 | 28 |
| Jimmy Gobble* | PHI | mr | 26 | 5.33 | 1 | 0 | 0 | 38 | 0 | 0 | 0 | 25.1 | 34 | 16 | 15 | 14 | 20 | 1 | 4 |
| Edgar Gonzalez | CWS | mr | 25 | 8.57 | 0 | 2 | 1 | 9 | 2 | 0 | 0 | 21.0 | 37 | 20 | 20 | 8 | 20 | 2 | 2 |
| Tom Gorzelanny* | PIT | sp | 25 | 4.90 | 7 | 10 | 0 | 25 | 25 | 1 | 0 | 145.0 | 157 | 90 | 79 | 61 | 102 | 11 | 11 |
| John Grabow* | NYM | mr | 29 | 4.15 | 0 | 1 | 2 | 10 | 0 | 0 | 0 | 13.0 | 10 | 6 | 6 | 5 | 9 | 0 | 0 |
| Sean Green | MIL | mr | 29 | 6.75 | 1 | 6 | 0 | 33 | 0 | 0 | 0 | 40.0 | 52 | 30 | 30 | 28 | 33 | 0 | 5 |
| Kevin Gregg | CAL | cl | 30 | 4.63 | 0 | 6 | 26 | 48 | 0 | 0 | 0 | 58.1 | 52 | 30 | 30 | 45 | 60 | 4 | 7 |
| Zack Greinke | CHI | mr | 24 | 4.38 | 5 | 6 | 0 | 18 | 18 | 1 | 1 | 109.0 | 111 | 59 | 53 | 24 | 93 | 16 | 8 |
| Jason Grilli | SFG | mr | 31 | 4.47 | 1 | 2 | 2 | 30 | 0 | 0 | 0 | 46.1 | 42 | 28 | 23 | 15 | 31 | 4 | 3 |
| Matt Guerrier | PHI | mr | 29 | 2.33 | 5 | 2 | 4 | 69 | 0 | 0 | 0 | 81.0 | 53 | 24 | 21 | 20 | 70 | 5 | 7 |
| Jeremy Guthrie | CHI | sp | 29 | 3.39 | 13 | 5 | 0 | 27 | 27 | 1 | 1 | 178.0 | 151 | 73 | 67 | 35 | 141 | 22 | 8 |
| Roy Halladay | NYA | sp | 31 | 2.93 | 20 | 5 | 0 | 34 | 34 | 2 | 2 | 230.2 | 216 | 81 | 75 | 44 | 158 | 13 | 27 |
| Cole Hamels* | MIN | sp | 24 | 4.00 | 15 | 7 | 0 | 30 | 29 | 1 | 1 | 180.0 | 168 | 88 | 80 | 41 | 201 | 20 | 11 |
| Jason Hammel | NYM | sp | 25 | 3.38 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 5.1 | 7 | 4 | 2 | 3 | 1 | 0 | 2 |
| Justin Hampson* | CWS | mr | 28 | 4.33 | 3 | 2 | 1 | 43 | 0 | 0 | 0 | 43.2 | 50 | 26 | 21 | 19 | 38 | 2 | 7 |
| Joel Hanrahan | PHI | sp | 26 | 7.46 | 0 | 4 | 0 | 9 | 9 | 0 | 0 | 41.0 | 47 | 37 | 34 | 33 | 32 | 12 | 5 |
| Aaron Harang | STL | sp | 30 | 4.05 | 19 | 8 | 0 | 34 | 34 | 6 | 1 | 231.0 | 210 | 111 | 104 | 50 | 232 | 28 | 17 |
| Rich Harden | WAS | sp | 26 | 7.88 | 0 | 1 | 2 | 14 | 0 | 0 | 0 | 16.0 | 19 | 15 | 14 | 12 | 14 | 3 | 2 |
| Dan Haren | LAD | sp | 27 | 2.85 | 6 | 6 | 0 | 18 | 18 | 1 | 1 | 123.0 | 119 | 48 | 39 | 17 | 106 | 12 | 4 |
| Dan Haren | CAL | sp | 27 | 5.07 | 3 | 8 | 0 | 15 | 15 | 1 | 0 | 97.2 | 108 | 58 | 55 | 36 | 103 | 10 | 5 |
| Dan Haren |   | sp | 27 | 3.83 | 9 | 14 | 0 | 33 | 33 | 2 | 1 | 220.2 | 227 | 106 | 94 | 53 | 209 | 22 | 9 |
| LaTroy Hawkins | SFG | mr | 35 | 3.69 | 0 | 2 | 2 | 33 | 0 | 0 | 0 | 46.1 | 42 | 23 | 19 | 19 | 20 | 2 | 10 |
| Aaron Heilman | LAD | mr | 29 | 3.74 | 3 | 0 | 5 | 68 | 0 | 0 | 0 | 74.2 | 73 | 31 | 31 | 30 | 41 | 8 | 4 |
| Mark Hendrickson* | WAS | mr | 34 | 5.24 | 3 | 2 | 2 | 61 | 2 | 0 | 0 | 111.2 | 130 | 70 | 65 | 48 | 71 | 9 | 10 |
| Brad Hennessey | PHI | cl | 28 | 4.13 | 4 | 4 | 0 | 52 | 0 | 0 | 0 | 69.2 | 65 | 37 | 32 | 26 | 46 | 6 | 9 |
| Matt Herges | NYA | mr | 38 | 1.26 | 7 | 2 | 3 | 43 | 0 | 0 | 0 | 50.0 | 24 | 7 | 7 | 16 | 20 | 1 | 12 |
| Felix Hernandez | DET | sp | 22 | 5.45 | 12 | 10 | 0 | 26 | 26 | 0 | 0 | 153.2 | 194 | 97 | 93 | 56 | 157 | 24 | 24 |
| Livan Hernandez | BOS | sp | 33 | 6.23 | 4 | 6 | 0 | 17 | 17 | 0 | 0 | 91.0 | 105 | 70 | 63 | 47 | 51 | 15 | 9 |
| Orlando Hernandez | NYM | sp | 38 | 4.18 | 7 | 5 | 1 | 25 | 23 | 1 | 1 | 140.0 | 126 | 75 | 65 | 61 | 121 | 31 | 9 |
| Rich Hill* | BAL | sp | 28 | 4.44 | 6 | 14 | 0 | 32 | 32 | 2 | 2 | 184.2 | 169 | 100 | 91 | 67 | 194 | 31 | 17 |
| Shawn Hill | LAD | sp | 27 | 4.05 | 7 | 4 | 0 | 15 | 14 | 0 | 0 | 91.0 | 96 | 47 | 41 | 27 | 62 | 10 | 9 |
| Jason Hirsh | CHI | sp | 26 | 6.12 | 7 | 8 | 0 | 21 | 18 | 1 | 1 | 100.0 | 97 | 70 | 68 | 43 | 79 | 20 | 5 |
| Trevor Hoffman | BAL | cl | 40 | 3.74 | 6 | 5 | 8 | 38 | 0 | 0 | 0 | 43.1 | 40 | 19 | 18 | 11 | 42 | 5 | 3 |
| J.P. Howell* | CIN | sp | 25 | 6.89 | 4 | 4 | 0 | 14 | 9 | 0 | 0 | 49.2 | 78 | 41 | 38 | 18 | 42 | 11 | 4 |
| Bob Howry | CIN | mr | 34 | 3.18 | 9 | 1 | 1 | 61 | 0 | 0 | 0 | 79.1 | 79 | 29 | 28 | 12 | 58 | 10 | 2 |
| Tim Hudson | PHI | sp | 32 | 3.23 | 10 | 2 | 0 | 13 | 13 | 2 | 1 | 94.2 | 90 | 36 | 34 | 18 | 63 | 4 | 8 |
| Tim Hudson | KCA | sp | 32 | 2.43 | 11 | 0 | 0 | 18 | 18 | 1 | 1 | 118.1 | 109 | 37 | 32 | 26 | 72 | 10 | 17 |
| Tim Hudson |   | sp | 32 | 2.79 | 21 | 2 | 0 | 31 | 31 | 3 | 2 | 213.0 | 199 | 73 | 66 | 44 | 135 | 14 | 25 |
| Phil Hughes | CIN | sp | 22 | 5.23 | 0 | 1 | 0 | 4 | 4 | 0 | 0 | 20.2 | 22 | 14 | 12 | 9 | 19 | 2 | 2 |
| Phil Hughes | CLE | sp | 22 | 1.67 | 3 | 1 | 0 | 8 | 8 | 0 | 0 | 54.0 | 22 | 12 | 10 | 22 | 45 | 3 | 4 |
| Phil Hughes |   | sp | 22 | 2.65 | 3 | 2 | 0 | 12 | 12 | 0 | 0 | 74.2 | 44 | 26 | 22 | 31 | 64 | 5 | 6 |
| Jason Isringhausen | STL | cl | 35 | 1.93 | 3 | 4 | 36 | 61 | 0 | 0 | 0 | 65.1 | 38 | 15 | 14 | 23 | 50 | 5 | 9 |
| Edwin Jackson | MIL | sp | 24 | 6.56 | 3 | 12 | 0 | 35 | 23 | 0 | 0 | 130.1 | 173 | 105 | 95 | 71 | 115 | 21 | 6 |
| Chuck James* | KCA | sp | 26 | 4.10 | 7 | 4 | 0 | 17 | 16 | 0 | 0 | 96.2 | 78 | 47 | 44 | 42 | 72 | 14 | 2 |
| Casey Janssen | HOU | mr | 26 | 3.43 | 1 | 2 | 14 | 33 | 0 | 0 | 0 | 39.1 | 50 | 20 | 15 | 9 | 27 | 3 | 5 |
| Casey Janssen | STL | mr | 26 | 3.18 | 3 | 1 | 2 | 23 | 0 | 0 | 0 | 28.1 | 30 | 11 | 10 | 7 | 16 | 1 | 7 |
| Casey Janssen |   | mr | 26 | 3.33 | 4 | 3 | 16 | 56 | 0 | 0 | 0 | 67.2 | 80 | 31 | 25 | 16 | 43 | 4 | 12 |
| Bobby Jenks | DET | cl | 27 | 2.53 | 7 | 4 | 29 | 57 | 0 | 0 | 0 | 57.0 | 54 | 18 | 16 | 16 | 49 | 1 | 6 |
| Jason Jennings | PIT | sp | 29 | 18.00 | 0 | 1 | 0 | 2 | 0 | 0 | 0 | 2.0 | 7 | 5 | 4 | 1 | 1 | 1 | 0 |
| Ubaldo Jimenez | LAD | sp | 24 | 3.72 | 2 | 1 | 0 | 5 | 3 | 0 | 0 | 19.1 | 19 | 8 | 8 | 9 | 18 | 1 | 3 |
| Ubaldo Jimenez | CAL | sp | 24 | 2.70 | 6 | 2 | 0 | 9 | 9 | 0 | 0 | 63.1 | 47 | 24 | 19 | 29 | 46 | 4 | 3 |
| Ubaldo Jimenez |   | sp | 24 | 2.94 | 8 | 3 | 0 | 14 | 12 | 0 | 0 | 82.2 | 66 | 32 | 27 | 38 | 64 | 5 | 6 |
| Josh Johnson | MIL | sp | 24 | 7.45 | 1 | 2 | 0 | 5 | 5 | 0 | 0 | 19.1 | 30 | 16 | 16 | 10 | 9 | 1 | 4 |
| Randy Johnson* | KCA | sp | 44 | 4.37 | 4 | 2 | 0 | 17 | 6 | 0 | 0 | 45.1 | 42 | 24 | 22 | 16 | 69 | 5 | 3 |
| Tyler Johnson* | STL | mr | 27 | 2.45 | 2 | 2 | 1 | 45 | 0 | 0 | 0 | 36.2 | 28 | 12 | 10 | 13 | 29 | 3 | 0 |
| Todd Jones | CIN | cl | 40 | 4.18 | 3 | 0 | 1 | 39 | 0 | 0 | 0 | 47.1 | 45 | 23 | 22 | 13 | 23 | 5 | 8 |
| Jorge Julio | BAL | mr | 29 | 6.60 | 9 | 1 | 2 | 39 | 0 | 0 | 0 | 45.0 | 56 | 33 | 33 | 26 | 46 | 9 | 3 |
| Scott Kazmir* | CIN | sp | 24 | 5.97 | 0 | 12 | 0 | 17 | 17 | 0 | 0 | 86.0 | 88 | 60 | 57 | 49 | 117 | 10 | 7 |
| Scott Kazmir* | CLE | sp | 24 | 4.08 | 5 | 6 | 0 | 16 | 16 | 1 | 1 | 103.2 | 88 | 50 | 47 | 40 | 134 | 14 | 8 |
| Scott Kazmir* |   | sp | 24 | 4.93 | 5 | 18 | 0 | 33 | 33 | 1 | 1 | 189.2 | 176 | 110 | 104 | 89 | 251 | 24 | 15 |
| Kyle Kendrick | MIL | sp | 23 | 4.56 | 5 | 8 | 0 | 15 | 15 | 1 | 0 | 102.2 | 110 | 57 | 52 | 17 | 30 | 16 | 14 |
| Joe Kennedy* | LAD | mr | 29 | 3.86 | 0 | 1 | 0 | 3 | 2 | 1 | 0 | 14.0 | 15 | 7 | 6 | 3 | 2 | 3 | 1 |
| Logan Kensing | PIT | mr | 25 | 6.97 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 10.1 | 18 | 8 | 8 | 2 | 9 | 3 | 1 |
| Ray King* | NYM | mr | 34 | 7.56 | 0 | 0 | 1 | 34 | 0 | 0 | 0 | 33.1 | 51 | 29 | 28 | 17 | 17 | 5 | 7 |
| John Lackey | KCA | sp | 29 | 3.32 | 18 | 3 | 0 | 33 | 33 | 1 | 1 | 208.2 | 182 | 81 | 77 | 52 | 184 | 14 | 17 |
| Aaron Laffey* | HOU | sp | 23 | 2.79 | 0 | 2 | 1 | 9 | 3 | 0 | 0 | 29.0 | 34 | 12 | 9 | 4 | 13 | 1 | 7 |
| Aaron Laffey* | STL | sp | 23 | 3.86 | 0 | 0 | 0 | 4 | 4 | 0 | 0 | 18.2 | 21 | 9 | 8 | 5 | 12 | 0 | 1 |
| Aaron Laffey* |   | sp | 23 | 3.21 | 0 | 2 | 1 | 13 | 7 | 0 | 0 | 47.2 | 55 | 21 | 17 | 9 | 25 | 1 | 8 |
| John Lannan* | SFG | sp | 23 | 15.75 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 4.0 | 6 | 7 | 7 | 5 | 1 | 2 | 0 |
| John Lannan* | WAS | sp | 23 | 7.54 | 1 | 2 | 0 | 6 | 3 | 0 | 0 | 22.2 | 26 | 19 | 19 | 17 | 8 | 2 | 1 |
| John Lannan* |   | sp | 23 | 8.77 | 1 | 3 | 0 | 7 | 4 | 0 | 0 | 26.2 | 32 | 26 | 26 | 22 | 9 | 4 | 1 |
| Brandon League | WAS | mr | 25 | 1.69 | 0 | 0 | 0 | 9 | 0 | 0 | 0 | 10.2 | 11 | 2 | 2 | 2 | 4 | 1 | 1 |
| Cliff Lee* | PHI | sp | 29 | 5.38 | 5 | 4 | 1 | 67 | 0 | 0 | 0 | 100.1 | 100 | 60 | 60 | 39 | 65 | 21 | 12 |
| Jon Lester* | HOU | sp | 24 | 5.31 | 2 | 2 | 2 | 38 | 2 | 0 | 0 | 57.2 | 65 | 37 | 34 | 21 | 42 | 9 | 3 |
| Brad Lidge | PHI | cl | 31 | 3.36 | 3 | 3 | 42 | 60 | 0 | 0 | 0 | 59.0 | 41 | 23 | 22 | 21 | 71 | 4 | 2 |
| Jon Lieber | PHI | sp | 38 | 4.88 | 6 | 2 | 0 | 14 | 14 | 0 | 0 | 86.2 | 99 | 47 | 47 | 23 | 51 | 6 | 6 |
| Ted Lilly* | SFG | sp | 32 | 5.15 | 9 | 14 | 0 | 31 | 31 | 1 | 0 | 183.1 | 196 | 115 | 105 | 55 | 149 | 33 | 10 |
| Tim Lincecum | WAS | sp | 24 | 3.79 | 8 | 12 | 0 | 23 | 23 | 1 | 0 | 147.1 | 125 | 70 | 62 | 63 | 140 | 20 | 18 |
| Matt Lindstrom | CAL | mr | 28 | 2.48 | 4 | 2 | 1 | 45 | 0 | 0 | 0 | 61.2 | 55 | 17 | 17 | 18 | 56 | 3 | 4 |
| Scott Linebrink | CLE | mr | 31 | 6.43 | 2 | 6 | 4 | 62 | 0 | 0 | 0 | 63.0 | 67 | 45 | 45 | 30 | 45 | 16 | 5 |
| Jesse Litsch | LAD | sp | 23 | 5.40 | 1 | 1 | 0 | 4 | 4 | 0 | 0 | 23.1 | 32 | 14 | 14 | 5 | 8 | 2 | 4 |
| Jesse Litsch | CAL | sp | 23 | 3.70 | 6 | 3 | 0 | 14 | 14 | 0 | 0 | 90.0 | 93 | 37 | 37 | 22 | 47 | 10 | 20 |
| Jesse Litsch |   | sp | 23 | 4.05 | 7 | 4 | 0 | 18 | 18 | 0 | 0 | 113.1 | 125 | 51 | 51 | 27 | 55 | 12 | 24 |
| Wes Littleton | LAD | mr | 25 | 4.11 | 1 | 6 | 1 | 24 | 3 | 0 | 0 | 46.0 | 46 | 23 | 21 | 27 | 25 | 7 | 7 |
| Kameron Loe | NYM | sp | 26 | 3.65 | 2 | 0 | 0 | 2 | 2 | 0 | 0 | 12.1 | 9 | 5 | 5 | 6 | 12 | 0 | 1 |
| Adam Loewen* | NYM | sp | 24 | 4.54 | 3 | 3 | 0 | 6 | 6 | 0 | 0 | 35.2 | 33 | 18 | 18 | 32 | 25 | 1 | 7 |
| Boone Logan* | NYM | mr | 23 | 7.78 | 0 | 1 | 0 | 35 | 0 | 0 | 0 | 41.2 | 68 | 37 | 36 | 22 | 26 | 7 | 4 |
| Kyle Lohse | MIN | sp | 29 | 4.48 | 9 | 9 | 0 | 32 | 30 | 0 | 0 | 178.2 | 185 | 94 | 89 | 50 | 130 | 19 | 10 |
| Braden Looper | CAL | sp | 33 | 5.32 | 7 | 13 | 0 | 25 | 25 | 5 | 0 | 167.1 | 192 | 104 | 99 | 66 | 111 | 21 | 17 |
| Javier Lopez* | LAD | mr | 30 | 2.57 | 1 | 1 | 2 | 15 | 8 | 0 | 0 | 42.0 | 25 | 13 | 12 | 22 | 12 | 3 | 6 |
| Rodrigo Lopez | STL | sp | 32 | 5.56 | 5 | 3 | 0 | 13 | 13 | 1 | 0 | 79.1 | 92 | 51 | 49 | 20 | 40 | 13 | 4 |
| Derek Lowe | CWS | sp | 35 | 4.03 | 13 | 12 | 0 | 30 | 29 | 1 | 1 | 187.2 | 185 | 87 | 84 | 70 | 158 | 18 | 23 |
| Noah Lowry* | CAL | sp | 27 | 7.61 | 2 | 8 | 0 | 12 | 12 | 1 | 0 | 75.2 | 101 | 71 | 64 | 53 | 53 | 13 | 16 |
| Brandon Lyon | MIN | mr | 28 | 3.30 | 9 | 7 | 16 | 60 | 0 | 0 | 0 | 71.0 | 71 | 26 | 26 | 23 | 42 | 2 | 6 |
| Greg Maddux | BAL | sp | 42 | 4.48 | 12 | 11 | 0 | 30 | 30 | 0 | 0 | 192.2 | 225 | 105 | 96 | 35 | 106 | 16 | 17 |
| Ryan Madson | CAL | mr | 27 | 5.40 | 2 | 4 | 3 | 36 | 0 | 0 | 0 | 50.0 | 59 | 36 | 30 | 24 | 33 | 7 | 5 |
| Ron Mahay* | CAL | mr | 37 | 5.06 | 1 | 2 | 2 | 47 | 0 | 0 | 0 | 48.0 | 58 | 27 | 27 | 32 | 57 | 6 | 2 |
| Paul Maholm* | PHI | sp | 26 | 5.68 | 7 | 9 | 0 | 32 | 30 | 2 | 0 | 160.0 | 197 | 116 | 101 | 62 | 91 | 29 | 27 |
| John Maine | PHI | sp | 27 | 5.00 | 12 | 12 | 0 | 32 | 31 | 1 | 0 | 181.2 | 194 | 108 | 101 | 62 | 173 | 34 | 15 |
| Shaun Marcum | CHI | sp | 26 | 4.95 | 11 | 6 | 0 | 25 | 25 | 0 | 0 | 152.2 | 167 | 86 | 84 | 41 | 121 | 29 | 17 |
| Carlos Marmol | CHI | mr | 25 | 3.95 | 6 | 3 | 8 | 64 | 0 | 0 | 0 | 68.1 | 44 | 33 | 30 | 39 | 90 | 9 | 4 |
| Jason Marquis | HOU | sp | 29 | 3.88 | 12 | 10 | 0 | 32 | 29 | 5 | 4 | 190.0 | 170 | 90 | 82 | 63 | 106 | 13 | 23 |
| Sean Marshall* | NYM | sp | 25 | 6.18 | 5 | 7 | 0 | 19 | 19 | 0 | 0 | 99.0 | 122 | 70 | 68 | 36 | 62 | 16 | 8 |
| Damaso Marte* | MIL | mr | 33 | 3.71 | 0 | 0 | 0 | 38 | 0 | 0 | 0 | 43.2 | 42 | 20 | 18 | 15 | 48 | 5 | 2 |
| Pedro Martinez | NYA | sp | 36 | 8.02 | 2 | 1 | 0 | 5 | 5 | 0 | 0 | 21.1 | 34 | 19 | 19 | 3 | 24 | 0 | 1 |
| Daisuke Matsuzaka | DET | sp | 27 | 4.90 | 13 | 6 | 0 | 30 | 30 | 0 | 0 | 176.1 | 171 | 99 | 96 | 68 | 196 | 35 | 15 |
| Brandon McCarthy | DET | sp | 24 | 8.03 | 3 | 3 | 0 | 31 | 8 | 0 | 0 | 80.2 | 100 | 76 | 72 | 50 | 50 | 17 | 9 |
| Dustin McGowan | NYA | sp | 26 | 3.75 | 12 | 4 | 0 | 26 | 26 | 2 | 1 | 160.2 | 140 | 80 | 67 | 54 | 153 | 12 | 7 |
| Gil Meche | CHI | sp | 29 | 3.72 | 17 | 6 | 0 | 32 | 32 | 1 | 1 | 210.1 | 194 | 93 | 87 | 47 | 151 | 29 | 19 |
| Cla Meredith | DET | mr | 25 | 3.07 | 2 | 1 | 1 | 62 | 0 | 0 | 0 | 67.1 | 70 | 24 | 23 | 19 | 44 | 8 | 15 |
| Andrew Miller* | HOU | sp | 23 | 4.43 | 5 | 7 | 2 | 49 | 0 | 0 | 0 | 63.0 | 70 | 36 | 31 | 33 | 64 | 9 | 3 |
| Justin Miller | HOU | mr | 30 | 4.33 | 6 | 2 | 7 | 47 | 0 | 0 | 0 | 62.1 | 58 | 33 | 30 | 16 | 55 | 7 | 5 |
| Trever Miller* | BOS | mr | 35 | 7.56 | 1 | 0 | 2 | 19 | 0 | 0 | 0 | 16.2 | 24 | 14 | 14 | 10 | 22 | 1 | 2 |
| Kevin Millwood | BAL | sp | 33 | 3.76 | 7 | 12 | 0 | 30 | 30 | 2 | 2 | 184.1 | 175 | 97 | 77 | 62 | 128 | 19 | 23 |
| Zach Miner | KCA | mr | 26 | 1.70 | 7 | 0 | 0 | 14 | 8 | 0 | 0 | 58.1 | 35 | 13 | 11 | 22 | 38 | 1 | 6 |
| Sergio Mitre | PHI | sp | 27 | 5.33 | 11 | 4 | 0 | 23 | 23 | 2 | 0 | 128.1 | 157 | 86 | 76 | 41 | 67 | 13 | 15 |
| Brian Moehler | NYM | mr | 36 | 5.48 | 1 | 3 | 1 | 12 | 0 | 0 | 0 | 21.1 | 25 | 13 | 13 | 8 | 14 | 1 | 4 |
| Franklin Morales* | BOS | sp | 22 | 3.94 | 2 | 2 | 0 | 5 | 4 | 1 | 0 | 29.2 | 27 | 13 | 13 | 16 | 21 | 2 | 10 |
| Matt Morris | NYM | sp | 33 | 6.02 | 8 | 18 | 0 | 35 | 32 | 1 | 0 | 190.0 | 244 | 139 | 127 | 73 | 79 | 20 | 18 |
| Brandon Morrow | NYM | mr | 23 | 9.17 | 1 | 4 | 5 | 45 | 0 | 0 | 0 | 53.0 | 66 | 55 | 54 | 50 | 54 | 4 | 5 |
| Dustin Moseley | NYA | mr | 26 | 2.43 | 6 | 1 | 1 | 13 | 10 | 2 | 2 | 70.1 | 57 | 20 | 19 | 18 | 55 | 3 | 8 |
| Guillermo Mota | CLE | mr | 34 | 5.77 | 3 | 2 | 3 | 30 | 0 | 0 | 0 | 39.0 | 47 | 27 | 25 | 13 | 39 | 7 | 2 |
| Jamie Moyer* | BOS | sp | 45 | 6.51 | 4 | 19 | 0 | 32 | 31 | 1 | 0 | 166.0 | 210 | 130 | 120 | 63 | 125 | 27 | 13 |
| Peter Moylan | PIT | mr | 29 | 3.63 | 8 | 6 | 30 | 69 | 0 | 0 | 0 | 86.2 | 90 | 37 | 35 | 19 | 54 | 9 | 18 |
| Mike Mussina | CLE | sp | 39 | 4.51 | 8 | 7 | 0 | 27 | 25 | 1 | 0 | 147.2 | 184 | 82 | 74 | 29 | 104 | 13 | 17 |
| Brett Myers | LAD | cl | 27 | 3.49 | 5 | 2 | 0 | 14 | 11 | 0 | 0 | 67.0 | 51 | 26 | 26 | 30 | 77 | 4 | 2 |
| Joe Nathan | MIL | cl | 33 | 3.23 | 2 | 3 | 8 | 36 | 0 | 0 | 0 | 39.0 | 35 | 16 | 14 | 15 | 41 | 3 | 6 |
| Joe Nathan | MIN | cl | 33 | 1.00 | 3 | 1 | 10 | 23 | 0 | 0 | 0 | 27.0 | 24 | 3 | 3 | 10 | 29 | 0 | 2 |
| Joe Nathan |   | cl | 33 | 2.32 | 5 | 4 | 18 | 59 | 0 | 0 | 0 | 66.0 | 59 | 19 | 17 | 25 | 70 | 3 | 8 |
| Pat Neshek | CIN | mr | 27 | 5.26 | 3 | 2 | 2 | 33 | 0 | 0 | 0 | 39.1 | 40 | 24 | 23 | 12 | 53 | 7 | 0 |
| Pat Neshek | STL | mr | 27 | 2.86 | 4 | 1 | 2 | 25 | 0 | 0 | 0 | 28.1 | 16 | 10 | 9 | 8 | 37 | 5 | 3 |
| Pat Neshek |   | mr | 27 | 4.26 | 7 | 3 | 4 | 58 | 0 | 0 | 0 | 67.2 | 56 | 34 | 32 | 20 | 90 | 12 | 3 |
| Dustin Nippert | CWS | mr | 27 | 20.25 | 0 | 1 | 0 | 5 | 0 | 0 | 0 | 2.2 | 6 | 6 | 6 | 4 | 2 | 0 | 0 |
| Leo Nunez | CWS | mr | 24 | 3.38 | 2 | 1 | 1 | 9 | 3 | 1 | 0 | 26.2 | 28 | 11 | 10 | 11 | 28 | 3 | 1 |
| Eric O'Flaherty* | PHI | mr | 23 | 3.22 | 3 | 3 | 0 | 46 | 0 | 0 | 0 | 44.2 | 41 | 18 | 16 | 11 | 21 | 4 | 6 |
| Hideki Okajima* | CHI | mr | 32 | 3.25 | 5 | 2 | 3 | 41 | 0 | 0 | 0 | 55.1 | 53 | 20 | 20 | 9 | 58 | 10 | 4 |
| Darren Oliver* | BAL | mr | 37 | 3.19 | 6 | 2 | 3 | 40 | 0 | 0 | 0 | 53.2 | 44 | 19 | 19 | 24 | 39 | 5 | 4 |
| Scott Olsen* | MIL | sp | 24 | 8.48 | 1 | 3 | 0 | 23 | 5 | 0 | 0 | 52.0 | 81 | 49 | 49 | 21 | 34 | 11 | 4 |
| Scott Olsen* | WAS | sp | 24 | 5.74 | 3 | 11 | 0 | 17 | 17 | 0 | 0 | 95.2 | 107 | 71 | 61 | 61 | 70 | 10 | 7 |
| Scott Olsen* |   | sp | 24 | 6.70 | 4 | 14 | 0 | 40 | 22 | 0 | 0 | 147.2 | 188 | 120 | 110 | 82 | 104 | 21 | 11 |
| Garrett Olson* | WAS | sp | 24 | 11.48 | 0 | 4 | 0 | 12 | 5 | 0 | 0 | 29.0 | 49 | 37 | 37 | 26 | 21 | 8 | 4 |
| Ramon Ortiz | LAD | mr | 35 | 3.55 | 0 | 1 | 0 | 3 | 1 | 0 | 0 | 12.2 | 14 | 5 | 5 | 1 | 3 | 1 | 2 |
| Roy Oswalt | CWS | sp | 30 | 4.25 | 13 | 8 | 0 | 29 | 29 | 3 | 1 | 186.1 | 189 | 91 | 88 | 67 | 141 | 14 | 18 |
| Akinori Otsuka | NYA | mr | 36 | 3.70 | 0 | 2 | 0 | 22 | 0 | 0 | 0 | 24.1 | 19 | 10 | 10 | 8 | 28 | 1 | 2 |
| Micah Owings | MIN | sp | 25 | 4.57 | 10 | 8 | 3 | 31 | 23 | 0 | 0 | 145.2 | 149 | 88 | 74 | 57 | 129 | 24 | 14 |
| Vicente Padilla | BOS | sp | 30 | 8.50 | 2 | 7 | 1 | 15 | 12 | 0 | 0 | 60.1 | 81 | 59 | 57 | 34 | 43 | 13 | 10 |
| Vicente Padilla | MIN | sp | 30 | 5.49 | 2 | 1 | 2 | 21 | 3 | 0 | 0 | 39.1 | 61 | 26 | 24 | 9 | 26 | 2 | 2 |
| Vicente Padilla |   | sp | 30 | 7.31 | 4 | 8 | 3 | 36 | 15 | 0 | 0 | 99.2 | 142 | 85 | 81 | 43 | 69 | 15 | 12 |
| Jonathan Papelbon | NYA | cl | 27 | 3.42 | 4 | 7 | 32 | 55 | 0 | 0 | 0 | 55.1 | 38 | 21 | 21 | 16 | 79 | 10 | 0 |
| Chad Paronto | MIL | mr | 32 | 10.03 | 0 | 5 | 0 | 12 | 0 | 0 | 0 | 11.2 | 17 | 14 | 13 | 7 | 3 | 0 | 2 |
| John Patterson | CWS | sp | 30 | 4.15 | 1 | 2 | 0 | 4 | 4 | 1 | 1 | 26.0 | 25 | 12 | 12 | 13 | 12 | 1 | 5 |
| Jake Peavy | CHI | sp | 27 | 3.15 | 18 | 4 | 0 | 31 | 31 | 3 | 1 | 220.1 | 192 | 85 | 77 | 46 | 214 | 22 | 15 |
| Mike Pelfrey | MIL | sp | 24 | 5.01 | 2 | 0 | 1 | 37 | 1 | 0 | 0 | 55.2 | 65 | 35 | 31 | 36 | 41 | 5 | 14 |
| Tony Pena | STL | mr | 26 | 4.35 | 6 | 5 | 2 | 68 | 0 | 0 | 0 | 78.2 | 64 | 41 | 38 | 31 | 50 | 11 | 6 |
| Brad Penny | SFG | sp | 30 | 5.63 | 6 | 6 | 0 | 18 | 18 | 0 | 0 | 102.1 | 125 | 71 | 64 | 42 | 73 | 13 | 11 |
| Brad Penny | DET | sp | 30 | 4.80 | 6 | 4 | 0 | 12 | 12 | 0 | 0 | 69.1 | 70 | 41 | 37 | 30 | 37 | 9 | 8 |
| Brad Penny |   | sp | 30 | 5.30 | 12 | 10 | 0 | 30 | 30 | 0 | 0 | 171.2 | 195 | 112 | 101 | 72 | 110 | 22 | 19 |
| Joel Peralta | BAL | mr | 32 | 3.40 | 4 | 2 | 3 | 51 | 0 | 0 | 0 | 76.2 | 76 | 30 | 29 | 11 | 63 | 11 | 9 |
| Troy Percival | CHI | mr | 38 | 3.25 | 4 | 2 | 2 | 38 | 0 | 0 | 0 | 36.0 | 33 | 13 | 13 | 10 | 43 | 6 | 1 |
| Odalis Perez* | LAD | sp | 31 | 5.63 | 0 | 3 | 0 | 3 | 2 | 0 | 0 | 16.0 | 16 | 16 | 10 | 12 | 3 | 2 | 1 |
| Oliver Perez* | MIL | sp | 26 | 6.61 | 4 | 8 | 0 | 18 | 18 | 0 | 0 | 99.1 | 125 | 80 | 73 | 56 | 92 | 23 | 7 |
| Oliver Perez* | CLE | sp | 26 | 3.34 | 3 | 4 | 0 | 10 | 9 | 0 | 0 | 62.0 | 45 | 23 | 23 | 26 | 62 | 8 | 2 |
| Oliver Perez* |   | sp | 26 | 5.36 | 7 | 12 | 0 | 28 | 27 | 0 | 0 | 161.1 | 170 | 103 | 96 | 82 | 154 | 31 | 9 |
| Rafael Perez* | KCA | mr | 26 | 3.42 | 4 | 7 | 3 | 47 | 0 | 0 | 0 | 55.1 | 38 | 22 | 21 | 16 | 56 | 6 | 5 |
| Yusmeiro Petit | WAS | sp | 23 | 4.13 | 4 | 5 | 4 | 35 | 3 | 0 | 0 | 52.1 | 49 | 27 | 24 | 14 | 39 | 13 | 6 |
| Andy Pettitte* | PIT | sp | 36 | 3.38 | 10 | 12 | 0 | 31 | 31 | 2 | 1 | 202.2 | 196 | 93 | 76 | 52 | 146 | 16 | 27 |
| Joel Pineiro | MIN | mr | 29 | 5.62 | 4 | 8 | 0 | 37 | 7 | 0 | 0 | 73.2 | 94 | 57 | 46 | 32 | 35 | 19 | 12 |
| Renyel Pinto* | DET | mr | 25 | 3.63 | 4 | 1 | 2 | 58 | 0 | 0 | 0 | 44.2 | 42 | 19 | 18 | 28 | 51 | 2 | 6 |
| Scott Proctor | LAD | mr | 31 | 4.70 | 3 | 7 | 4 | 65 | 0 | 0 | 0 | 84.1 | 82 | 48 | 44 | 37 | 66 | 15 | 4 |
| J.J. Putz | CHI | cl | 31 | 1.65 | 3 | 6 | 35 | 60 | 0 | 0 | 0 | 71.0 | 35 | 16 | 13 | 19 | 68 | 6 | 5 |
| Chad Qualls | MIN | mr | 29 | 5.12 | 0 | 3 | 5 | 52 | 0 | 0 | 0 | 65.0 | 81 | 41 | 37 | 21 | 73 | 7 | 3 |
| Jon Rauch | LAD | mr | 29 | 3.98 | 5 | 7 | 15 | 60 | 0 | 0 | 0 | 74.2 | 66 | 34 | 33 | 31 | 54 | 5 | 8 |
| Jon Rauch | NYA | mr | 29 | 4.61 | 1 | 0 | 0 | 12 | 0 | 0 | 0 | 13.2 | 20 | 8 | 7 | 2 | 14 | 2 | 2 |
| Jon Rauch |   | mr | 29 | 4.08 | 6 | 7 | 15 | 72 | 0 | 0 | 0 | 88.1 | 86 | 42 | 40 | 33 | 68 | 7 | 10 |
| Chris Ray | DET | cl | 26 | 7.02 | 0 | 2 | 3 | 26 | 0 | 0 | 0 | 33.1 | 37 | 26 | 26 | 20 | 30 | 5 | 1 |
| Tim Redding | STL | sp | 30 | 7.68 | 4 | 2 | 0 | 14 | 14 | 0 | 0 | 70.1 | 98 | 60 | 60 | 42 | 49 | 9 | 7 |
| Al Reyes | CIN | cl | 38 | 4.53 | 7 | 5 | 5 | 48 | 0 | 0 | 0 | 57.2 | 50 | 31 | 29 | 27 | 56 | 9 | 5 |
| Anthony Reyes | MIN | sp | 26 | 5.77 | 0 | 0 | 1 | 26 | 0 | 0 | 0 | 34.1 | 41 | 23 | 22 | 20 | 30 | 9 | 2 |
| Jo-Jo Reyes* | WAS | sp | 23 | 7.14 | 1 | 4 | 1 | 16 | 4 | 0 | 0 | 46.2 | 64 | 42 | 37 | 33 | 24 | 12 | 7 |
| John Rheinecker* | NYM | mr | 29 | 6.00 | 1 | 5 | 0 | 17 | 9 | 0 | 0 | 51.0 | 63 | 35 | 34 | 27 | 34 | 10 | 8 |
| Juan Rincon | STL | mr | 29 | 3.46 | 0 | 0 | 2 | 37 | 0 | 0 | 0 | 41.2 | 37 | 17 | 16 | 12 | 30 | 7 | 1 |
| David Riske | CAL | mr | 31 | 3.21 | 4 | 5 | 1 | 52 | 0 | 0 | 0 | 61.2 | 60 | 26 | 22 | 22 | 39 | 3 | 4 |
| Mariano Rivera | NYA | cl | 38 | 2.73 | 6 | 2 | 1 | 55 | 0 | 0 | 0 | 59.1 | 52 | 19 | 18 | 15 | 58 | 2 | 5 |
| Saul Rivera | CWS | mr | 30 | 5.79 | 2 | 1 | 2 | 19 | 0 | 0 | 0 | 28.0 | 29 | 18 | 18 | 11 | 24 | 1 | 4 |
| Nate Robertson* | HOU | sp | 30 | 5.66 | 4 | 17 | 0 | 32 | 29 | 1 | 1 | 168.2 | 225 | 115 | 106 | 66 | 108 | 11 | 18 |
| Fernando Rodney | CHI | mr | 31 | 4.15 | 7 | 1 | 4 | 47 | 0 | 0 | 0 | 43.1 | 36 | 25 | 20 | 16 | 44 | 7 | 4 |
| Francisco Rodriguez | SFG | cl | 26 | 4.55 | 5 | 3 | 7 | 53 | 0 | 0 | 0 | 61.1 | 53 | 35 | 31 | 26 | 81 | 7 | 3 |
| Wandy Rodriguez* | LAD | sp | 29 | 3.99 | 10 | 9 | 0 | 28 | 28 | 0 | 0 | 182.2 | 182 | 90 | 81 | 48 | 152 | 18 | 12 |
| Kenny Rogers* | CHI | sp | 43 | 3.52 | 2 | 3 | 0 | 10 | 8 | 0 | 0 | 53.2 | 53 | 22 | 21 | 18 | 31 | 5 | 6 |
| J.C. Romero* | CLE | mr | 32 | 4.59 | 2 | 9 | 8 | 68 | 0 | 0 | 0 | 51.0 | 43 | 31 | 26 | 34 | 46 | 5 | 6 |
| Ryan Rowland-Smith* | WAS | mr | 25 | 5.03 | 3 | 5 | 7 | 28 | 0 | 0 | 0 | 34.0 | 33 | 20 | 19 | 21 | 33 | 3 | 5 |
| C.C. Sabathia* | NYA | sp | 27 | 4.45 | 19 | 9 | 0 | 33 | 33 | 4 | 1 | 232.2 | 258 | 119 | 115 | 37 | 217 | 25 | 26 |
| Takashi Saito | SFG | cl | 38 | 3.31 | 7 | 5 | 16 | 43 | 0 | 0 | 0 | 51.2 | 35 | 19 | 19 | 13 | 63 | 9 | 6 |
| Juan Salas | NYM | mr | 29 | 5.88 | 1 | 4 | 1 | 23 | 0 | 0 | 0 | 26.0 | 23 | 18 | 17 | 5 | 21 | 7 | 0 |
| Chris Sampson | BOS | sp | 30 | 6.37 | 5 | 6 | 4 | 45 | 3 | 1 | 0 | 89.0 | 104 | 65 | 63 | 37 | 43 | 17 | 9 |
| Anibal Sanchez | CAL | sp | 24 | 6.75 | 0 | 2 | 0 | 9 | 1 | 0 | 0 | 22.2 | 35 | 19 | 17 | 13 | 10 | 1 | 3 |
| Jonathan Sanchez* | HOU | mr | 25 | 6.65 | 5 | 4 | 3 | 44 | 0 | 0 | 0 | 44.2 | 77 | 38 | 33 | 27 | 53 | 6 | 4 |
| Ervin Santana | HOU | sp | 25 | 5.88 | 5 | 11 | 0 | 35 | 24 | 0 | 0 | 142.1 | 177 | 101 | 93 | 55 | 116 | 25 | 9 |
| Johan Santana* | KCA | sp | 29 | 3.48 | 14 | 9 | 0 | 33 | 33 | 4 | 0 | 214.2 | 166 | 84 | 83 | 48 | 244 | 38 | 11 |
| Joe Saunders* | PHI | sp | 27 | 4.99 | 7 | 8 | 0 | 17 | 16 | 1 | 0 | 95.2 | 126 | 72 | 53 | 33 | 58 | 7 | 14 |
| Curt Schilling | BAL | sp | 41 | 4.44 | 4 | 8 | 0 | 23 | 23 | 0 | 0 | 144.0 | 178 | 74 | 71 | 25 | 108 | 21 | 9 |
| Scott Schoeneweis* | BOS | mr | 34 | 0.00 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 6.0 | 4 | 0 | 0 | 2 | 5 | 0 | 1 |
| Chris Schroder | CLE | mr | 29 | 6.39 | 3 | 5 | 4 | 33 | 0 | 0 | 0 | 38.0 | 59 | 30 | 27 | 20 | 42 | 4 | 2 |
| Rudy Seanez | BOS | mr | 39 | 6.84 | 0 | 1 | 7 | 37 | 0 | 0 | 0 | 52.2 | 52 | 43 | 40 | 28 | 56 | 10 | 4 |
| Bobby Seay* | DET | mr | 30 | 3.09 | 8 | 3 | 2 | 57 | 0 | 0 | 0 | 43.2 | 41 | 15 | 15 | 17 | 45 | 1 | 6 |
| Ben Sheets | KCA | sp | 29 | 3.08 | 12 | 2 | 0 | 20 | 20 | 0 | 0 | 128.2 | 119 | 49 | 44 | 37 | 117 | 9 | 6 |
| George Sherrill* | CHI | mr | 31 | 3.03 | 3 | 2 | 3 | 48 | 0 | 0 | 0 | 38.2 | 39 | 14 | 13 | 17 | 42 | 5 | 4 |
| James Shields | CWS | sp | 26 | 4.22 | 10 | 9 | 0 | 31 | 31 | 1 | 1 | 198.1 | 190 | 94 | 93 | 41 | 223 | 23 | 6 |
| Scot Shields | PHI | mr | 32 | 2.51 | 5 | 3 | 7 | 66 | 0 | 0 | 0 | 75.1 | 55 | 24 | 21 | 28 | 64 | 7 | 8 |
| Brian Shouse* | DET | mr | 39 | 3.57 | 2 | 1 | 1 | 40 | 0 | 0 | 0 | 35.1 | 41 | 16 | 14 | 10 | 26 | 1 | 4 |
| Carlos Silva | BOS | sp | 29 | 5.68 | 6 | 4 | 0 | 18 | 18 | 0 | 0 | 103.0 | 142 | 77 | 65 | 34 | 59 | 14 | 9 |
| Carlos Silva | MIN | sp | 29 | 3.90 | 9 | 2 | 0 | 13 | 13 | 1 | 1 | 80.2 | 88 | 41 | 35 | 13 | 35 | 8 | 9 |
| Carlos Silva |   | sp | 29 | 4.90 | 15 | 6 | 0 | 31 | 31 | 1 | 1 | 183.2 | 230 | 118 | 100 | 47 | 94 | 22 | 18 |
| Doug Slaten* | NYM | mr | 28 | 8.24 | 0 | 0 | 0 | 24 | 0 | 0 | 0 | 19.2 | 31 | 19 | 18 | 13 | 10 | 5 | 1 |
| Kevin Slowey | BOS | sp | 24 | 5.48 | 2 | 7 | 0 | 12 | 12 | 0 | 0 | 67.1 | 71 | 49 | 41 | 19 | 55 | 20 | 2 |
| Joe Smith | CIN | mr | 24 | 6.07 | 3 | 2 | 0 | 43 | 0 | 0 | 0 | 43.0 | 52 | 31 | 29 | 19 | 46 | 3 | 6 |
| John Smoltz | STL | sp | 41 | 3.97 | 19 | 9 | 0 | 33 | 31 | 2 | 0 | 201.2 | 203 | 95 | 89 | 50 | 233 | 29 | 9 |
| Ian Snell | MIL | sp | 26 | 4.66 | 1 | 10 | 0 | 19 | 12 | 0 | 0 | 85.0 | 94 | 55 | 44 | 27 | 66 | 8 | 9 |
| Ian Snell | HOU | sp | 26 | 4.84 | 4 | 10 | 0 | 16 | 16 | 0 | 0 | 100.1 | 113 | 59 | 54 | 34 | 79 | 11 | 6 |
| Ian Snell |   | sp | 26 | 4.76 | 5 | 20 | 0 | 35 | 28 | 0 | 0 | 185.1 | 207 | 114 | 98 | 61 | 145 | 19 | 15 |
| Kyle Snyder | BOS | mr | 30 | 3.72 | 3 | 3 | 1 | 49 | 0 | 0 | 0 | 55.2 | 39 | 23 | 23 | 28 | 41 | 13 | 2 |
| Andy Sonnanstine | CIN | sp | 25 | 6.18 | 7 | 9 | 0 | 22 | 22 | 0 | 0 | 118.0 | 167 | 85 | 81 | 25 | 89 | 21 | 10 |
| Joakim Soria | KCA | cl | 24 | 2.04 | 4 | 1 | 36 | 55 | 0 | 0 | 0 | 61.2 | 51 | 14 | 14 | 13 | 66 | 4 | 4 |
| Rafael Soriano | KCA | mr | 28 | 2.33 | 6 | 1 | 2 | 52 | 0 | 0 | 0 | 58.0 | 44 | 16 | 15 | 12 | 53 | 8 | 3 |
| Jorge Sosa | SFG | mr | 31 | 7.40 | 0 | 4 | 1 | 25 | 4 | 0 | 0 | 48.2 | 70 | 45 | 40 | 29 | 27 | 5 | 8 |
| Jeremy Sowers* | NYM | sp | 25 | 6.99 | 3 | 6 | 0 | 14 | 14 | 0 | 0 | 67.0 | 92 | 60 | 52 | 21 | 33 | 16 | 2 |
| Jeremy Sowers* | STL | sp | 25 | 14.21 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 6.1 | 15 | 10 | 10 | 0 | 2 | 3 | 0 |
| Jeremy Sowers* |   | sp | 25 | 7.61 | 3 | 7 | 0 | 16 | 16 | 0 | 0 | 73.1 | 107 | 70 | 62 | 21 | 35 | 19 | 2 |
| Justin Speier | SFG | mr | 34 | 3.60 | 1 | 3 | 2 | 38 | 0 | 0 | 0 | 50.0 | 46 | 24 | 20 | 8 | 37 | 8 | 1 |
| Russ Springer | BAL | mr | 39 | 2.75 | 1 | 3 | 2 | 38 | 0 | 0 | 0 | 52.1 | 38 | 17 | 16 | 16 | 57 | 4 | 6 |
| Huston Street | CWS | cl | 24 | 4.03 | 5 | 7 | 23 | 45 | 0 | 0 | 0 | 44.2 | 37 | 22 | 20 | 11 | 52 | 9 | 2 |
| Jeff Suppan | SFG | sp | 33 | 5.37 | 12 | 8 | 0 | 32 | 32 | 1 | 0 | 182.2 | 226 | 122 | 109 | 58 | 105 | 18 | 25 |
| Brian Tallet* | SFG | mr | 30 | 2.30 | 2 | 1 | 3 | 48 | 0 | 0 | 0 | 62.2 | 59 | 17 | 16 | 23 | 52 | 5 | 4 |
| Taylor Tankersley* | MIL | mr | 25 | 5.02 | 2 | 1 | 2 | 43 | 0 | 0 | 0 | 37.2 | 42 | 23 | 21 | 22 | 41 | 8 | 2 |
| Jack Taschner* | LAD | mr | 30 | 7.38 | 3 | 5 | 3 | 48 | 1 | 0 | 0 | 42.2 | 48 | 35 | 35 | 33 | 46 | 6 | 2 |
| Julian Tavarez | MIL | sp | 35 | 4.85 | 0 | 3 | 0 | 16 | 4 | 0 | 0 | 42.2 | 57 | 23 | 23 | 9 | 29 | 4 | 5 |
| Brad Thompson | LAD | mr | 26 | 9.53 | 0 | 1 | 0 | 3 | 1 | 1 | 0 | 11.1 | 19 | 12 | 12 | 4 | 6 | 2 | 0 |
| Matt Thornton* | CHI | mr | 31 | 1.69 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 5.1 | 3 | 1 | 1 | 0 | 7 | 0 | 0 |
| Mike Timlin | DET | mr | 42 | 2.22 | 4 | 2 | 4 | 44 | 0 | 0 | 0 | 52.2 | 45 | 15 | 13 | 9 | 31 | 4 | 4 |
| Josh Towers | CIN | sp | 31 | 4.12 | 3 | 9 | 4 | 60 | 2 | 0 | 0 | 91.2 | 101 | 45 | 42 | 16 | 61 | 14 | 11 |
| Steve Trachsel | MIL | sp | 37 | 8.53 | 2 | 7 | 0 | 13 | 10 | 0 | 0 | 50.2 | 72 | 49 | 48 | 33 | 21 | 9 | 5 |
| Derrick Turnbow | NYA | mr | 30 | 5.27 | 1 | 1 | 2 | 34 | 0 | 0 | 0 | 41.0 | 32 | 24 | 24 | 22 | 49 | 6 | 1 |
| Jose Valverde | CWS | cl | 28 | 3.60 | 3 | 7 | 12 | 54 | 0 | 0 | 0 | 60.0 | 47 | 25 | 24 | 23 | 77 | 8 | 4 |
| Rick VandenHurk | HOU | sp | 23 | 7.01 | 4 | 6 | 2 | 57 | 3 | 0 | 0 | 77.0 | 100 | 68 | 60 | 42 | 81 | 20 | 6 |
| Claudio Vargas | BAL | sp | 30 | 5.12 | 4 | 11 | 0 | 21 | 20 | 0 | 0 | 114.1 | 125 | 72 | 65 | 61 | 93 | 18 | 8 |
| Javier Vazquez | CWS | sp | 31 | 3.34 | 12 | 11 | 0 | 31 | 31 | 3 | 1 | 199.2 | 169 | 86 | 74 | 63 | 220 | 25 | 19 |
| Justin Verlander | STL | sp | 25 | 4.22 | 18 | 7 | 0 | 33 | 33 | 1 | 0 | 211.0 | 195 | 105 | 99 | 66 | 174 | 32 | 10 |
| Carlos Villanueva | STL | mr | 24 | 5.42 | 3 | 4 | 1 | 53 | 5 | 1 | 0 | 103.0 | 114 | 65 | 62 | 48 | 90 | 19 | 16 |
| Oscar Villarreal | PIT | mr | 26 | 4.77 | 9 | 2 | 3 | 57 | 0 | 0 | 0 | 77.1 | 82 | 45 | 41 | 21 | 60 | 10 | 2 |
| Ron Villone* | KCA | mr | 38 | 3.82 | 0 | 5 | 3 | 31 | 0 | 0 | 0 | 40.0 | 35 | 19 | 17 | 14 | 35 | 3 | 4 |
| Luis Vizcaino | MIN | mr | 33 | 4.57 | 2 | 1 | 2 | 57 | 0 | 0 | 0 | 61.0 | 53 | 34 | 31 | 29 | 44 | 7 | 4 |
| Billy Wagner* | NYA | cl | 36 | 2.87 | 3 | 1 | 2 | 56 | 0 | 0 | 0 | 53.1 | 49 | 17 | 17 | 17 | 71 | 7 | 3 |
| Adam Wainwright | PIT | sp | 26 | 4.58 | 14 | 7 | 0 | 32 | 32 | 1 | 0 | 192.2 | 224 | 115 | 98 | 54 | 143 | 13 | 15 |
| Tim Wakefield | CLE | sp | 41 | 4.95 | 3 | 7 | 0 | 16 | 16 | 0 | 0 | 100.0 | 108 | 56 | 55 | 36 | 55 | 14 | 15 |
| Tim Wakefield | MIN | sp | 41 | 5.40 | 6 | 5 | 0 | 13 | 13 | 0 | 0 | 78.1 | 83 | 50 | 47 | 24 | 49 | 13 | 10 |
| Tim Wakefield |   | sp | 41 | 5.15 | 9 | 12 | 0 | 29 | 29 | 0 | 0 | 178.1 | 191 | 106 | 102 | 60 | 104 | 27 | 25 |
| Jamie Walker* | BOS | mr | 36 | 4.29 | 2 | 6 | 0 | 53 | 0 | 0 | 0 | 56.2 | 57 | 28 | 27 | 20 | 34 | 4 | 1 |
| Chien-Ming Wang | CLE | sp | 28 | 3.33 | 12 | 7 | 0 | 29 | 29 | 1 | 1 | 197.1 | 180 | 78 | 73 | 63 | 100 | 10 | 28 |
| Jarrod Washburn* | BOS | sp | 33 | 5.45 | 8 | 10 | 0 | 29 | 29 | 1 | 0 | 175.0 | 211 | 115 | 106 | 65 | 115 | 36 | 22 |
| David Weathers | CIN | cl | 38 | 3.16 | 2 | 4 | 19 | 69 | 0 | 0 | 0 | 74.0 | 71 | 29 | 26 | 30 | 31 | 6 | 8 |
| Jered Weaver | PHI | sp | 25 | 3.59 | 13 | 3 | 0 | 26 | 26 | 1 | 0 | 165.1 | 155 | 72 | 66 | 42 | 124 | 21 | 6 |
| Brandon Webb | SFG | sp | 29 | 4.11 | 8 | 7 | 0 | 18 | 18 | 1 | 0 | 118.1 | 128 | 62 | 54 | 31 | 115 | 9 | 11 |
| Brandon Webb | WAS | sp | 29 | 5.46 | 3 | 6 | 0 | 14 | 14 | 3 | 0 | 90.2 | 102 | 58 | 55 | 34 | 81 | 16 | 12 |
| Brandon Webb |   | sp | 29 | 4.69 | 11 | 13 | 0 | 32 | 32 | 4 | 0 | 209.0 | 230 | 120 | 109 | 65 | 196 | 25 | 23 |
| Todd Wellemeyer | BOS | mr | 29 | 5.57 | 6 | 3 | 1 | 50 | 0 | 0 | 0 | 76.0 | 84 | 51 | 47 | 40 | 66 | 17 | 8 |
| Kip Wells | HOU | sp | 31 | 5.11 | 4 | 4 | 1 | 18 | 13 | 1 | 0 | 79.1 | 92 | 47 | 45 | 29 | 58 | 11 | 8 |
| Jake Westbrook | MIN | sp | 30 | 5.40 | 9 | 7 | 0 | 27 | 22 | 0 | 0 | 136.2 | 147 | 90 | 82 | 39 | 86 | 20 | 13 |
| Dan Wheeler | CIN | mr | 30 | 4.99 | 4 | 1 | 1 | 60 | 0 | 0 | 0 | 70.1 | 80 | 42 | 39 | 15 | 77 | 12 | 7 |
| Bob Wickman | SFG | cl | 39 | 6.07 | 2 | 2 | 2 | 19 | 0 | 0 | 0 | 26.2 | 33 | 20 | 18 | 14 | 12 | 3 | 3 |
| Woody Williams | BOS | sp | 41 | 8.33 | 1 | 3 | 0 | 16 | 5 | 0 | 0 | 54.0 | 75 | 52 | 50 | 23 | 34 | 11 | 2 |
| Dontrelle Willis* | CLE | sp | 26 | 6.23 | 7 | 18 | 0 | 34 | 34 | 0 | 0 | 182.0 | 235 | 133 | 126 | 87 | 138 | 27 | 17 |
| C.J. Wilson* | CIN | mr | 27 | 2.97 | 3 | 0 | 2 | 61 | 0 | 0 | 0 | 66.2 | 53 | 25 | 22 | 37 | 50 | 5 | 14 |
| Matt Wise | MIL | mr | 32 | 7.04 | 1 | 3 | 0 | 20 | 0 | 0 | 0 | 23.0 | 27 | 18 | 18 | 14 | 17 | 3 | 3 |
| Randy Wolf* | HOU | sp | 31 | 5.02 | 3 | 5 | 1 | 42 | 9 | 0 | 0 | 98.2 | 109 | 64 | 55 | 35 | 89 | 17 | 6 |
| Brian Wolfe | DET | mr | 27 | 4.30 | 1 | 1 | 2 | 26 | 0 | 0 | 0 | 23.0 | 23 | 11 | 11 | 5 | 11 | 5 | 1 |
| Kerry Wood | BOS | mr | 31 | 3.63 | 3 | 1 | 6 | 22 | 0 | 0 | 0 | 22.1 | 13 | 10 | 9 | 17 | 15 | 2 | 1 |
| Jamey Wright | MIL | mr | 33 | 3.65 | 4 | 0 | 1 | 47 | 0 | 0 | 0 | 69.0 | 58 | 29 | 28 | 38 | 36 | 6 | 7 |
| Michael Wuertz | LAD | mr | 29 | 4.24 | 2 | 3 | 7 | 65 | 0 | 0 | 0 | 70.0 | 79 | 34 | 33 | 25 | 81 | 8 | 7 |
| Tyler Yates | NYM | mr | 30 | 3.51 | 2 | 2 | 1 | 28 | 0 | 0 | 0 | 33.1 | 31 | 18 | 13 | 21 | 31 | 1 | 2 |
| Chris Young | CWS | sp | 29 | 3.01 | 10 | 6 | 0 | 29 | 28 | 0 | 0 | 167.2 | 129 | 60 | 56 | 83 | 163 | 10 | 10 |
| Carlos Zambrano | CAL | sp | 27 | 3.80 | 12 | 14 | 0 | 31 | 31 | 2 | 0 | 208.2 | 202 | 103 | 88 | 107 | 173 | 18 | 28 |
| Barry Zito* | PIT | sp | 30 | 3.71 | 14 | 6 | 0 | 32 | 32 | 3 | 2 | 191.2 | 186 | 93 | 79 | 61 | 128 | 19 | 10 |
| Joel Zumaya | DET | mr | 23 | 2.10 | 2 | 0 | 1 | 30 | 0 | 0 | 0 | 34.1 | 25 | 8 | 8 | 19 | 36 | 3 | 4 |
| Secondary |
| Name | Team | P | Age | SB | CS | IW | HBP | WP | BK | SH | SF | H/9 | BB/9 | R/9 | K/9 | HR/9 | K/BB | WHIP |
| Jeremy Accardo | CHI | cl | 26 | 4 | 1 | 1 | 4 | 0 | 2 | 4 | 1 | 10.5 | 4.0 | 15.2 | 7.7 | 1.3 | 1.9 | 1.61 |
| Jeremy Affeldt* | CWS | mr | 29 | 3 | 1 | 3 | 3 | 2 | 1 | 1 | 1 | 7.7 | 6.5 | 14.7 | 8.4 | 0.5 | 1.3 | 1.58 |
| Bronson Arroyo | SFG | sp | 31 | 13 | 7 | 2 | 12 | 2 | 0 | 4 | 9 | 11.7 | 2.6 | 14.9 | 7.2 | 1.3 | 2.8 | 1.58 |
| Luis Ayala | CWS | mr | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.0 | 6.2 | 15.2 | 5.7 | 1.9 | 0.9 | 1.68 |
| Cha Seung Baek | NYM | sp | 28 | 4 | 2 | 3 | 4 | 1 | 0 | 3 | 5 | 13.5 | 2.3 | 16.4 | 6.0 | 0.5 | 2.6 | 1.76 |
| Homer Bailey | HOU | sp | 22 | 4 | 2 | 3 | 2 | 3 | 0 | 0 | 4 | 9.7 | 5.7 | 15.8 | 4.1 | 0.4 | 0.7 | 1.71 |
| Scott Baker | MIL | sp | 26 | 4 | 3 | 3 | 4 | 0 | 0 | 3 | 3 | 12.3 | 2.0 | 14.6 | 5.8 | 1.9 | 2.9 | 1.59 |
| John Bale* | SFG | mr | 34 | 1 | 2 | 1 | 1 | 1 | 0 | 0 | 0 | 8.1 | 1.1 | 9.5 | 11.6 | 0.4 | 11.0 | 1.01 |
| Brian Bannister | HOU | sp | 27 | 5 | 7 | 5 | 6 | 4 | 0 | 7 | 8 | 9.1 | 2.6 | 12.0 | 3.8 | 0.6 | 1.5 | 1.29 |
| Miguel Batista | PIT | sp | 37 | 5 | 1 | 5 | 3 | 5 | 1 | 1 | 1 | 8.8 | 3.7 | 12.9 | 7.4 | 0.7 | 2.0 | 1.39 |
| Josh Beckett | WAS | sp | 28 | 12 | 4 | 4 | 5 | 2 | 0 | 7 | 6 | 8.3 | 2.5 | 11.1 | 9.0 | 1.0 | 3.5 | 1.21 |
| Erik Bedard* | HOU | sp | 29 | 3 | 3 | 0 | 6 | 0 | 0 | 1 | 1 | 7.9 | 3.1 | 11.6 | 10.2 | 0.9 | 3.3 | 1.23 |
| Erik Bedard* | STL | sp | 29 | 1 | 3 | 0 | 0 | 0 | 0 | 5 | 0 | 9.2 | 2.8 | 11.9 | 11.1 | 1.7 | 4.0 | 1.33 |
| Erik Bedard* |   | sp | 29 | 4 | 6 | 0 | 6 | 0 | 0 | 6 | 1 | 8.5 | 3.0 | 11.8 | 10.6 | 1.3 | 3.6 | 1.27 |
| Joe Beimel* | MIN | mr | 31 | 1 | 0 | 7 | 2 | 4 | 0 | 0 | 2 | 8.2 | 3.3 | 11.8 | 6.5 | 0.3 | 2.0 | 1.28 |
| Matt Belisle | SFG | sp | 28 | 5 | 2 | 2 | 4 | 2 | 1 | 5 | 2 | 12.8 | 2.1 | 15.5 | 6.1 | 2.3 | 2.8 | 1.65 |
| Heath Bell | KCA | mr | 30 | 3 | 3 | 2 | 3 | 5 | 0 | 5 | 0 | 6.3 | 3.5 | 10.2 | 9.5 | 0.7 | 2.7 | 1.09 |
| Joaquin Benoit | SFG | mr | 30 | 5 | 2 | 1 | 3 | 4 | 0 | 4 | 4 | 9.3 | 3.3 | 13.0 | 9.4 | 1.6 | 2.8 | 1.41 |
| Jason Bergmann | SFG | sp | 26 | 4 | 0 | 3 | 1 | 4 | 0 | 0 | 0 | 10.4 | 5.9 | 16.6 | 7.6 | 1.3 | 1.3 | 1.81 |
| Jason Bergmann | WAS | sp | 26 | 6 | 0 | 1 | 0 | 1 | 0 | 2 | 1 | 9.3 | 5.0 | 14.3 | 9.3 | 3.0 | 1.9 | 1.59 |
| Jason Bergmann |   | sp | 26 | 10 | 0 | 4 | 1 | 5 | 0 | 2 | 1 | 9.8 | 5.3 | 15.2 | 8.7 | 2.3 | 1.6 | 1.68 |
| Rafael Betancourt | BOS | mr | 33 | 1 | 1 | 1 | 2 | 0 | 0 | 1 | 1 | 7.6 | 1.6 | 9.7 | 9.4 | 0.8 | 5.8 | 1.02 |
| Rafael Betancourt | MIN | mr | 33 | 5 | 1 | 1 | 0 | 0 | 0 | 0 | 3 | 7.3 | 0.7 | 8.0 | 10.3 | 0.9 | 15.0 | 0.89 |
| Rafael Betancourt |   | mr | 33 | 6 | 2 | 2 | 2 | 0 | 0 | 1 | 4 | 7.4 | 1.1 | 8.8 | 9.9 | 0.9 | 8.9 | 0.95 |
| Chad Billingsley | CLE | mr | 23 | 9 | 2 | 2 | 3 | 7 | 0 | 1 | 7 | 7.9 | 4.4 | 12.6 | 7.5 | 1.0 | 1.7 | 1.38 |
| Joe Blanton | DET | sp | 27 | 4 | 2 | 3 | 4 | 3 | 1 | 9 | 5 | 11.6 | 2.4 | 14.2 | 5.8 | 1.5 | 2.4 | 1.55 |
| Jeremy Bonderman | DET | sp | 25 | 5 | 0 | 1 | 2 | 5 | 0 | 6 | 1 | 9.9 | 2.5 | 12.5 | 8.4 | 1.2 | 3.3 | 1.38 |
| Boof Bonser | CIN | sp | 26 | 10 | 4 | 3 | 9 | 1 | 6 | 9 | 1 | 10.4 | 3.0 | 13.9 | 7.5 | 2.2 | 2.5 | 1.49 |
| Dave Borkowski | BOS | mr | 31 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 9.0 | 4.5 | 13.5 | 3.4 | 2.3 | 0.8 | 1.50 |
| Joe Borowski | BAL | cl | 37 | 8 | 1 | 2 | 2 | 2 | 0 | 2 | 2 | 10.7 | 1.6 | 12.6 | 10.3 | 1.9 | 6.6 | 1.36 |
| Micah Bowie* | CWS | mr | 33 | 0 | 2 | 0 | 1 | 0 | 0 | 2 | 1 | 7.3 | 1.5 | 9.0 | 9.5 | 0.5 | 6.3 | 0.97 |
| Dallas Braden* | WAS | sp | 24 | 5 | 0 | 5 | 2 | 6 | 1 | 2 | 5 | 12.6 | 3.8 | 16.6 | 7.3 | 2.0 | 1.9 | 1.82 |
| Chad Bradford | BAL | mr | 33 | 2 | 1 | 4 | 8 | 0 | 0 | 2 | 5 | 11.9 | 1.8 | 15.1 | 3.6 | 1.1 | 2.0 | 1.52 |
| Doug Brocail | PIT | mr | 41 | 4 | 0 | 1 | 4 | 0 | 0 | 2 | 3 | 9.3 | 3.2 | 13.0 | 4.2 | 1.1 | 1.3 | 1.39 |
| Andrew Brown | LAD | mr | 27 | 2 | 2 | 1 | 0 | 3 | 0 | 2 | 2 | 9.1 | 3.0 | 12.1 | 8.5 | 0.4 | 2.9 | 1.35 |
| Jonathan Broxton | KCA | mr | 24 | 4 | 2 | 0 | 2 | 4 | 0 | 1 | 1 | 8.4 | 2.1 | 10.8 | 10.3 | 0.7 | 4.8 | 1.17 |
| Brian Bruney | WAS | mr | 26 | 0 | 1 | 2 | 3 | 7 | 0 | 0 | 3 | 13.0 | 8.3 | 22.1 | 7.8 | 2.1 | 0.9 | 2.37 |
| Taylor Buchholz | BAL | mr | 26 | 8 | 1 | 5 | 3 | 4 | 0 | 3 | 3 | 10.8 | 1.9 | 13.1 | 6.0 | 0.4 | 3.2 | 1.41 |
| Mark Buehrle* | CIN | sp | 29 | 4 | 4 | 0 | 3 | 0 | 0 | 3 | 2 | 8.7 | 3.1 | 12.0 | 5.2 | 0.9 | 1.7 | 1.30 |
| Mark Buehrle* | CLE | sp | 29 | 2 | 3 | 0 | 4 | 0 | 0 | 3 | 5 | 9.3 | 2.2 | 11.9 | 6.9 | 1.2 | 3.1 | 1.29 |
| Mark Buehrle* |   | sp | 29 | 6 | 7 | 0 | 7 | 0 | 0 | 6 | 7 | 9.0 | 2.6 | 12.0 | 6.1 | 1.1 | 2.4 | 1.29 |
| Ambiorix Burgos | MIL | mr | 24 | 0 | 1 | 2 | 4 | 2 | 0 | 3 | 1 | 4.3 | 3.4 | 9.0 | 9.0 | 0.9 | 2.6 | 0.86 |
| A.J. Burnett | MIL | sp | 31 | 5 | 1 | 1 | 3 | 2 | 0 | 4 | 2 | 8.0 | 1.7 | 10.0 | 9.4 | 1.1 | 5.7 | 1.07 |
| A.J. Burnett | NYA | sp | 31 | 12 | 1 | 1 | 3 | 2 | 0 | 2 | 2 | 8.4 | 3.8 | 12.6 | 7.7 | 0.8 | 2.0 | 1.36 |
| A.J. Burnett |   | sp | 31 | 17 | 2 | 2 | 6 | 4 | 0 | 6 | 4 | 8.2 | 2.7 | 11.2 | 8.6 | 1.0 | 3.2 | 1.21 |
| Brian Burres* | WAS | mr | 27 | 2 | 0 | 0 | 1 | 5 | 0 | 1 | 1 | 11.5 | 6.3 | 18.1 | 7.9 | 1.0 | 1.3 | 1.98 |
| Jared Burton | NYA | mr | 27 | 1 | 1 | 0 | 3 | 1 | 2 | 1 | 2 | 6.1 | 5.0 | 11.8 | 7.0 | 0.5 | 1.4 | 1.24 |
| Dave Bush | CIN | sp | 28 | 16 | 3 | 3 | 6 | 2 | 0 | 7 | 4 | 11.7 | 2.8 | 14.8 | 6.1 | 1.5 | 2.1 | 1.61 |
| Paul Byrd | NYM | sp | 37 | 11 | 0 | 1 | 6 | 2 | 0 | 2 | 4 | 10.7 | 1.4 | 12.7 | 4.8 | 1.4 | 3.4 | 1.34 |
| Tim Byrdak* | PIT | mr | 34 | 2 | 1 | 2 | 1 | 0 | 0 | 3 | 4 | 8.2 | 5.0 | 13.4 | 9.4 | 0.4 | 1.9 | 1.47 |
| Daniel Cabrera | WAS | sp | 27 | 15 | 3 | 6 | 8 | 12 | 2 | 10 | 7 | 9.6 | 5.2 | 15.2 | 7.5 | 1.1 | 1.5 | 1.64 |
| Matt Cain | LAD | sp | 23 | 11 | 6 | 3 | 3 | 7 | 0 | 3 | 4 | 7.5 | 4.3 | 12.0 | 7.8 | 1.1 | 1.8 | 1.31 |
| Matt Cain | CAL | sp | 23 | 7 | 3 | 2 | 4 | 8 | 0 | 4 | 3 | 10.8 | 4.6 | 15.9 | 7.3 | 1.0 | 1.6 | 1.71 |
| Matt Cain |   | sp | 23 | 18 | 9 | 5 | 7 | 15 | 0 | 7 | 7 | 8.8 | 4.5 | 13.5 | 7.6 | 1.1 | 1.7 | 1.47 |
| Kevin Cameron | CAL | mr | 28 | 3 | 2 | 1 | 1 | 1 | 0 | 3 | 4 | 9.0 | 6.9 | 16.1 | 8.0 | 0.3 | 1.1 | 1.77 |
| Matt Capps | CWS | mr | 24 | 2 | 0 | 2 | 0 | 0 | 0 | 1 | 3 | 6.5 | 1.3 | 7.8 | 6.4 | 0.4 | 5.0 | 0.87 |
| Chris Capuano* | BAL | sp | 29 | 3 | 4 | 1 | 3 | 11 | 0 | 7 | 2 | 11.6 | 5.0 | 16.8 | 8.4 | 2.1 | 1.7 | 1.85 |
| Fausto Carmona | PIT | sp | 24 | 10 | 2 | 3 | 15 | 6 | 2 | 3 | 2 | 7.6 | 1.9 | 10.1 | 6.5 | 0.5 | 3.4 | 1.06 |
| Chris Carpenter | MIN | sp | 33 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 1 | 8.3 | 10.4 | 18.7 | 0.0 | 2.1 | 0.0 | 2.08 |
| Santiago Casilla | STL | mr | 27 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 5.9 | 2.4 | 8.7 | 9.6 | 1.9 | 3.9 | 0.93 |
| Gustavo Chacin* | CHI | sp | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 21.9 | 4.2 | 26.2 | 6.8 | 5.9 | 1.6 | 2.91 |
| Shawn Chacon | NYM | mr | 30 | 6 | 2 | 3 | 4 | 0 | 0 | 6 | 8 | 11.0 | 4.2 | 15.5 | 6.4 | 1.1 | 1.5 | 1.68 |
| Matt Chico* | BOS | sp | 25 | 4 | 0 | 3 | 2 | 3 | 0 | 4 | 3 | 10.8 | 4.7 | 15.8 | 5.7 | 1.6 | 1.2 | 1.72 |
| Vinnie Chulk | DET | mr | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 8.8 | 2.6 | 11.4 | 6.9 | 1.1 | 2.7 | 1.26 |
| Roger Clemens | NYA | sp | 45 | 8 | 1 | 0 | 1 | 4 | 0 | 2 | 2 | 11.0 | 2.2 | 13.4 | 7.0 | 1.2 | 3.2 | 1.47 |
| Jesus Colome | CLE | mr | 30 | 7 | 0 | 3 | 2 | 2 | 0 | 1 | 5 | 11.4 | 4.6 | 16.3 | 6.0 | 0.3 | 1.3 | 1.77 |
| Jose Contreras | MIL | sp | 36 | 9 | 1 | 1 | 4 | 1 | 0 | 4 | 1 | 9.9 | 1.7 | 12.0 | 5.5 | 1.3 | 3.3 | 1.28 |
| Jose Contreras | CIN | sp | 36 | 4 | 3 | 4 | 9 | 2 | 0 | 5 | 3 | 11.5 | 2.5 | 14.8 | 4.3 | 1.7 | 1.7 | 1.55 |
| Jose Contreras |   | sp | 36 | 13 | 4 | 5 | 13 | 3 | 0 | 9 | 4 | 10.8 | 2.1 | 13.6 | 4.8 | 1.5 | 2.3 | 1.44 |
| Aaron Cook | MIN | sp | 29 | 7 | 2 | 0 | 4 | 0 | 0 | 4 | 3 | 10.9 | 2.1 | 13.3 | 4.0 | 0.6 | 1.9 | 1.45 |
| Chad Cordero | CLE | cl | 26 | 2 | 2 | 1 | 1 | 4 | 1 | 0 | 4 | 11.0 | 4.2 | 15.5 | 6.4 | 0.0 | 1.5 | 1.69 |
| Chad Cordero | DET | cl | 26 | 1 | 2 | 1 | 0 | 4 | 0 | 2 | 2 | 11.3 | 4.0 | 15.3 | 8.7 | 0.7 | 2.2 | 1.70 |
| Chad Cordero |   | cl | 26 | 3 | 4 | 2 | 1 | 8 | 1 | 2 | 6 | 11.2 | 4.1 | 15.4 | 7.4 | 0.3 | 1.8 | 1.70 |
| Francisco Cordero | NYA | cl | 33 | 3 | 2 | 1 | 2 | 2 | 0 | 3 | 1 | 8.4 | 4.1 | 12.8 | 11.3 | 0.7 | 2.8 | 1.39 |
| Manny Corpas | PIT | mr | 25 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 7.4 | 3.9 | 11.7 | 4.7 | 0.4 | 1.2 | 1.26 |
| Kevin Correia | LAD | mr | 27 | 10 | 6 | 1 | 3 | 1 | 1 | 2 | 2 | 7.6 | 3.2 | 11.1 | 7.4 | 0.5 | 2.3 | 1.20 |
| Neal Cotts* | CLE | mr | 28 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 1 | 7.9 | 5.3 | 14.8 | 8.5 | 0.5 | 1.6 | 1.47 |
| Juan Cruz | NYM | mr | 29 | 4 | 2 | 12 | 1 | 0 | 1 | 3 | 2 | 6.2 | 5.9 | 12.2 | 13.3 | 0.6 | 2.3 | 1.34 |
| John Danks* | BOS | sp | 23 | 3 | 1 | 4 | 1 | 5 | 0 | 2 | 5 | 10.2 | 2.9 | 13.1 | 8.2 | 2.3 | 2.9 | 1.45 |
| Kyle Davies | WAS | sp | 24 | 13 | 1 | 1 | 4 | 7 | 1 | 8 | 8 | 11.2 | 5.5 | 17.0 | 6.4 | 2.2 | 1.2 | 1.86 |
| Doug Davis* | MIL | sp | 32 | 8 | 5 | 7 | 3 | 7 | 0 | 7 | 3 | 12.1 | 4.7 | 16.9 | 6.9 | 1.0 | 1.5 | 1.86 |
| Jorge De La Rosa* | NYM | sp | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 9.0 | 0.0 | 9.0 | 3.4 | 1.1 | 99.0 | 1.00 |
| Manny Delcarmen | KCA | mr | 26 | 3 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 5.0 | 5.0 | 10.5 | 8.0 | 1.7 | 1.6 | 1.12 |
| Ryan Dempster | BAL | cl | 31 | 8 | 0 | 3 | 0 | 4 | 1 | 0 | 2 | 9.1 | 4.7 | 13.8 | 8.0 | 1.3 | 1.7 | 1.53 |
| Lenny DiNardo* | NYM | sp | 28 | 0 | 2 | 7 | 4 | 1 | 0 | 5 | 3 | 12.0 | 3.1 | 15.4 | 5.2 | 1.0 | 1.6 | 1.68 |
| Brendan Donnelly | BOS | mr | 36 | 0 | 0 | 2 | 7 | 1 | 0 | 1 | 0 | 10.0 | 2.9 | 17.0 | 6.5 | 0.0 | 2.2 | 1.43 |
| Scott Downs* | NYM | mr | 32 | 2 | 0 | 3 | 1 | 6 | 2 | 1 | 1 | 11.9 | 4.2 | 16.3 | 9.2 | 1.0 | 2.2 | 1.79 |
| Brandon Duckworth | CLE | mr | 32 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.9 | 6.9 | 10.8 | 2.3 | 0.0 | 0.3 | 1.20 |
| Zach Duke* | CHI | sp | 25 | 1 | 0 | 2 | 1 | 0 | 2 | 0 | 6 | 17.2 | 2.5 | 19.9 | 3.9 | 2.5 | 1.5 | 2.20 |
| Chad Durbin | NYM | sp | 30 | 9 | 0 | 3 | 16 | 0 | 0 | 6 | 4 | 10.4 | 2.3 | 13.8 | 4.6 | 1.5 | 2.0 | 1.40 |
| J.D. Durbin | WAS | sp | 26 | 2 | 3 | 0 | 1 | 5 | 0 | 2 | 2 | 9.0 | 3.5 | 12.6 | 6.8 | 0.7 | 2.0 | 1.38 |
| Alan Embree* | BOS | cl | 38 | 2 | 1 | 3 | 3 | 0 | 0 | 1 | 3 | 9.8 | 2.0 | 12.5 | 6.7 | 0.7 | 3.3 | 1.31 |
| Alan Embree* | MIN | cl | 38 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 9.4 | 2.0 | 11.5 | 4.7 | 0.7 | 2.3 | 1.27 |
| Alan Embree* |   | cl | 38 | 3 | 1 | 4 | 3 | 0 | 0 | 1 | 3 | 9.7 | 2.0 | 12.1 | 5.9 | 0.7 | 2.9 | 1.30 |
| Kelvim Escobar | NYA | sp | 32 | 12 | 1 | 2 | 4 | 9 | 0 | 4 | 4 | 8.2 | 2.9 | 11.3 | 7.6 | 0.8 | 2.6 | 1.23 |
| Kyle Farnsworth | CLE | mr | 32 | 2 | 2 | 0 | 2 | 1 | 2 | 0 | 4 | 6.9 | 4.2 | 11.4 | 7.6 | 1.7 | 1.8 | 1.23 |
| Pedro Feliciano* | STL | mr | 31 | 4 | 1 | 3 | 3 | 0 | 4 | 3 | 0 | 7.2 | 5.5 | 13.1 | 8.2 | 1.2 | 1.5 | 1.41 |
| Josh Fogg | SFG | sp | 31 | 9 | 2 | 2 | 4 | 1 | 0 | 3 | 2 | 14.2 | 3.0 | 17.8 | 5.8 | 1.1 | 1.9 | 1.91 |
| Jeff Francis* | DET | sp | 27 | 9 | 3 | 4 | 5 | 2 | 2 | 3 | 4 | 9.7 | 3.0 | 12.9 | 7.6 | 1.1 | 2.5 | 1.41 |
| Frank Francisco | PHI | mr | 28 | 1 | 1 | 3 | 2 | 4 | 0 | 4 | 1 | 10.4 | 5.0 | 15.8 | 8.8 | 1.0 | 1.8 | 1.71 |
| Ryan Franklin | CWS | mr | 35 | 0 | 0 | 2 | 1 | 0 | 0 | 1 | 5 | 8.6 | 2.6 | 11.3 | 5.9 | 1.0 | 2.3 | 1.24 |
| Jason Frasor | SFG | mr | 30 | 4 | 1 | 3 | 0 | 1 | 0 | 3 | 1 | 10.6 | 4.4 | 15.0 | 9.6 | 1.0 | 2.2 | 1.67 |
| Brian Fuentes* | LAD | cl | 32 | 2 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 10.9 | 8.4 | 19.3 | 8.4 | 0.6 | 1.0 | 2.14 |
| Brian Fuentes* | NYA | cl | 32 | 0 | 2 | 5 | 4 | 1 | 0 | 1 | 0 | 6.0 | 6.9 | 13.8 | 10.9 | 0.4 | 1.6 | 1.44 |
| Brian Fuentes* |   | cl | 32 | 2 | 3 | 6 | 4 | 2 | 0 | 1 | 1 | 7.3 | 7.3 | 15.2 | 10.3 | 0.5 | 1.4 | 1.62 |
| Aaron Fultz* | CAL | mr | 34 | 0 | 1 | 4 | 0 | 3 | 0 | 2 | 3 | 8.9 | 6.6 | 15.5 | 8.6 | 1.1 | 1.3 | 1.72 |
| Kason Gabbard* | CAL | sp | 26 | 7 | 0 | 2 | 4 | 5 | 0 | 7 | 2 | 7.7 | 4.3 | 12.5 | 7.1 | 1.0 | 1.6 | 1.33 |
| Eric Gagne | MIL | cl | 32 | 3 | 2 | 11 | 3 | 1 | 0 | 0 | 3 | 7.1 | 6.1 | 14.0 | 8.7 | 0.3 | 1.4 | 1.47 |
| Eric Gagne | BOS | cl | 32 | 0 | 2 | 3 | 1 | 0 | 0 | 0 | 2 | 12.9 | 8.2 | 21.7 | 7.0 | 1.8 | 0.9 | 2.35 |
| Eric Gagne |   | cl | 32 | 3 | 4 | 14 | 4 | 1 | 0 | 0 | 5 | 8.9 | 6.8 | 16.4 | 8.2 | 0.7 | 1.2 | 1.74 |
| Yovani Gallardo | MIL | sp | 22 | 1 | 0 | 0 | 0 | 2 | 0 | 1 | 5 | 12.0 | 3.7 | 15.7 | 8.0 | 0.9 | 2.2 | 1.74 |
| Yovani Gallardo | PIT | sp | 22 | 2 | 0 | 1 | 1 | 2 | 0 | 1 | 2 | 10.9 | 5.5 | 16.8 | 7.7 | 0.7 | 1.4 | 1.82 |
| Yovani Gallardo |   | sp | 22 | 3 | 0 | 1 | 1 | 4 | 0 | 2 | 7 | 11.7 | 4.2 | 16.0 | 7.9 | 0.8 | 1.9 | 1.77 |
| Lee Gardner | PIT | mr | 33 | 2 | 1 | 6 | 4 | 1 | 0 | 1 | 2 | 9.5 | 2.7 | 12.7 | 6.4 | 0.3 | 2.4 | 1.35 |
| Jon Garland | KCA | sp | 28 | 4 | 1 | 3 | 1 | 2 | 0 | 2 | 7 | 9.3 | 2.5 | 11.9 | 5.2 | 0.9 | 2.1 | 1.31 |
| Matt Garza | CAL | sp | 24 | 7 | 1 | 1 | 1 | 1 | 0 | 1 | 2 | 10.0 | 3.8 | 14.0 | 10.6 | 0.7 | 2.8 | 1.54 |
| Chad Gaudin | CIN | sp | 25 | 4 | 2 | 4 | 1 | 2 | 1 | 4 | 4 | 11.7 | 3.9 | 15.7 | 7.3 | 1.9 | 1.9 | 1.73 |
| Chad Gaudin | STL | sp | 25 | 5 | 1 | 0 | 3 | 0 | 0 | 4 | 2 | 10.5 | 2.9 | 13.7 | 7.7 | 1.9 | 2.7 | 1.49 |
| Chad Gaudin |   | sp | 25 | 9 | 3 | 4 | 4 | 2 | 1 | 8 | 6 | 11.1 | 3.4 | 14.7 | 7.5 | 1.9 | 2.2 | 1.61 |
| Geoff Geary | BOS | mr | 31 | 0 | 1 | 0 | 5 | 1 | 0 | 2 | 1 | 9.4 | 2.7 | 13.8 | 5.4 | 2.0 | 2.0 | 1.35 |
| Justin Germano | CAL | sp | 25 | 5 | 5 | 0 | 8 | 3 | 0 | 6 | 3 | 11.9 | 3.0 | 15.4 | 7.0 | 1.2 | 2.4 | 1.65 |
| Tom Glavine* | LAD | sp | 42 | 4 | 3 | 4 | 4 | 1 | 0 | 9 | 7 | 11.1 | 3.0 | 14.2 | 3.8 | 0.9 | 1.3 | 1.56 |
| Jimmy Gobble* | PHI | mr | 26 | 0 | 0 | 2 | 1 | 2 | 1 | 0 | 2 | 12.1 | 5.0 | 17.4 | 7.1 | 0.4 | 1.4 | 1.89 |
| Edgar Gonzalez | CWS | mr | 25 | 0 | 0 | 0 | 3 | 0 | 0 | 3 | 1 | 15.9 | 3.4 | 20.6 | 8.6 | 0.9 | 2.5 | 2.14 |
| Tom Gorzelanny* | PIT | sp | 25 | 6 | 1 | 5 | 12 | 1 | 2 | 7 | 7 | 9.7 | 3.8 | 14.3 | 6.3 | 0.7 | 1.7 | 1.50 |
| John Grabow* | NYM | mr | 29 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 3 | 6.9 | 3.5 | 11.1 | 6.2 | 0.0 | 1.8 | 1.15 |
| Sean Green | MIL | mr | 29 | 0 | 1 | 5 | 5 | 2 | 0 | 2 | 0 | 11.7 | 6.3 | 19.1 | 7.4 | 0.0 | 1.2 | 2.00 |
| Kevin Gregg | CAL | cl | 30 | 3 | 2 | 0 | 3 | 4 | 0 | 1 | 2 | 8.0 | 6.9 | 15.4 | 9.3 | 0.6 | 1.3 | 1.66 |
| Zack Greinke | CHI | mr | 24 | 9 | 5 | 1 | 2 | 1 | 3 | 1 | 6 | 9.2 | 2.0 | 11.3 | 7.7 | 1.3 | 3.9 | 1.24 |
| Jason Grilli | SFG | mr | 31 | 0 | 1 | 1 | 6 | 5 | 0 | 0 | 1 | 8.2 | 2.9 | 12.2 | 6.0 | 0.8 | 2.1 | 1.23 |
| Matt Guerrier | PHI | mr | 29 | 5 | 1 | 5 | 6 | 5 | 0 | 2 | 2 | 5.9 | 2.2 | 8.8 | 7.8 | 0.6 | 3.5 | 0.90 |
| Jeremy Guthrie | CHI | sp | 29 | 3 | 4 | 0 | 7 | 5 | 1 | 3 | 5 | 7.6 | 1.8 | 9.8 | 7.1 | 1.1 | 4.0 | 1.04 |
| Roy Halladay | NYA | sp | 31 | 7 | 9 | 0 | 6 | 5 | 0 | 3 | 4 | 8.4 | 1.7 | 10.4 | 6.2 | 0.5 | 3.6 | 1.13 |
| Cole Hamels* | MIN | sp | 24 | 16 | 5 | 2 | 4 | 5 | 0 | 3 | 2 | 8.4 | 2.0 | 10.6 | 10.0 | 1.0 | 4.9 | 1.16 |
| Jason Hammel | NYM | sp | 25 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 11.8 | 5.1 | 18.6 | 1.7 | 0.0 | 0.3 | 1.88 |
| Justin Hampson* | CWS | mr | 28 | 1 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 10.3 | 3.9 | 14.6 | 7.8 | 0.4 | 2.0 | 1.58 |
| Joel Hanrahan | PHI | sp | 26 | 1 | 2 | 1 | 0 | 1 | 0 | 3 | 2 | 10.3 | 7.2 | 17.6 | 7.0 | 2.6 | 1.0 | 1.95 |
| Aaron Harang | STL | sp | 30 | 17 | 6 | 1 | 5 | 6 | 0 | 5 | 5 | 8.2 | 1.9 | 10.3 | 9.0 | 1.1 | 4.6 | 1.13 |
| Rich Harden | WAS | sp | 26 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 0 | 10.7 | 6.8 | 17.4 | 7.9 | 1.7 | 1.2 | 1.94 |
| Dan Haren | LAD | sp | 27 | 12 | 3 | 4 | 2 | 6 | 0 | 4 | 2 | 8.7 | 1.2 | 10.1 | 7.8 | 0.9 | 6.2 | 1.11 |
| Dan Haren | CAL | sp | 27 | 7 | 0 | 3 | 1 | 5 | 0 | 4 | 0 | 10.0 | 3.3 | 13.4 | 9.5 | 0.9 | 2.9 | 1.47 |
| Dan Haren |   | sp | 27 | 19 | 3 | 7 | 3 | 11 | 0 | 8 | 2 | 9.3 | 2.2 | 11.5 | 8.5 | 0.9 | 3.9 | 1.27 |
| LaTroy Hawkins | SFG | mr | 35 | 4 | 1 | 0 | 1 | 0 | 0 | 2 | 2 | 8.2 | 3.7 | 12.0 | 3.9 | 0.4 | 1.1 | 1.32 |
| Aaron Heilman | LAD | mr | 29 | 5 | 1 | 4 | 3 | 2 | 0 | 2 | 4 | 8.8 | 3.6 | 12.8 | 4.9 | 1.0 | 1.4 | 1.38 |
| Mark Hendrickson* | WAS | mr | 34 | 9 | 4 | 4 | 0 | 3 | 0 | 4 | 7 | 10.5 | 3.9 | 14.3 | 5.7 | 0.7 | 1.5 | 1.59 |
| Brad Hennessey | PHI | cl | 28 | 2 | 1 | 4 | 2 | 1 | 0 | 2 | 7 | 8.4 | 3.4 | 12.0 | 5.9 | 0.8 | 1.8 | 1.31 |
| Matt Herges | NYA | mr | 38 | 3 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 4.3 | 2.9 | 7.4 | 3.6 | 0.2 | 1.3 | 0.80 |
| Felix Hernandez | DET | sp | 22 | 9 | 2 | 7 | 7 | 8 | 0 | 5 | 2 | 11.4 | 3.3 | 15.1 | 9.2 | 1.4 | 2.8 | 1.63 |
| Livan Hernandez | BOS | sp | 33 | 6 | 2 | 4 | 5 | 3 | 4 | 1 | 4 | 10.4 | 4.6 | 15.5 | 5.0 | 1.5 | 1.1 | 1.67 |
| Orlando Hernandez | NYM | sp | 38 | 14 | 1 | 1 | 5 | 1 | 0 | 3 | 4 | 8.1 | 3.9 | 12.3 | 7.8 | 2.0 | 2.0 | 1.34 |
| Rich Hill* | BAL | sp | 28 | 16 | 2 | 2 | 10 | 2 | 0 | 5 | 1 | 8.2 | 3.3 | 12.0 | 9.5 | 1.5 | 2.9 | 1.28 |
| Shawn Hill | LAD | sp | 27 | 4 | 2 | 3 | 5 | 0 | 0 | 1 | 3 | 9.5 | 2.7 | 12.7 | 6.1 | 1.0 | 2.3 | 1.35 |
| Jason Hirsh | CHI | sp | 26 | 2 | 3 | 2 | 9 | 8 | 0 | 7 | 4 | 8.7 | 3.9 | 13.4 | 7.1 | 1.8 | 1.8 | 1.40 |
| Trevor Hoffman | BAL | cl | 40 | 3 | 1 | 4 | 0 | 0 | 0 | 1 | 0 | 8.3 | 2.3 | 10.6 | 8.7 | 1.0 | 3.8 | 1.18 |
| J.P. Howell* | CIN | sp | 25 | 4 | 5 | 3 | 1 | 3 | 0 | 1 | 1 | 14.1 | 3.3 | 17.6 | 7.6 | 2.0 | 2.3 | 1.93 |
| Bob Howry | CIN | mr | 34 | 5 | 6 | 3 | 5 | 1 | 0 | 2 | 3 | 9.0 | 1.4 | 10.9 | 6.6 | 1.1 | 4.8 | 1.15 |
| Tim Hudson | PHI | sp | 32 | 3 | 5 | 1 | 2 | 0 | 0 | 3 | 2 | 8.6 | 1.7 | 10.5 | 6.0 | 0.4 | 3.5 | 1.14 |
| Tim Hudson | KCA | sp | 32 | 7 | 3 | 0 | 2 | 1 | 0 | 0 | 1 | 8.3 | 2.0 | 10.4 | 5.5 | 0.8 | 2.8 | 1.14 |
| Tim Hudson |   | sp | 32 | 10 | 8 | 1 | 4 | 1 | 0 | 3 | 3 | 8.4 | 1.9 | 10.4 | 5.7 | 0.6 | 3.1 | 1.14 |
| Phil Hughes | CIN | sp | 22 | 2 | 0 | 0 | 2 | 1 | 0 | 1 | 2 | 9.6 | 3.9 | 14.4 | 8.3 | 0.9 | 2.1 | 1.50 |
| Phil Hughes | CLE | sp | 22 | 2 | 0 | 2 | 4 | 3 | 0 | 2 | 1 | 3.7 | 3.7 | 8.0 | 7.5 | 0.5 | 2.0 | 0.81 |
| Phil Hughes |   | sp | 22 | 4 | 0 | 2 | 6 | 4 | 0 | 3 | 3 | 5.3 | 3.7 | 9.8 | 7.7 | 0.6 | 2.1 | 1.00 |
| Jason Isringhausen | STL | cl | 35 | 3 | 1 | 0 | 3 | 1 | 0 | 3 | 2 | 5.2 | 3.2 | 8.8 | 6.9 | 0.7 | 2.2 | 0.93 |
| Edwin Jackson | MIL | sp | 24 | 9 | 5 | 8 | 1 | 9 | 0 | 4 | 9 | 11.9 | 4.9 | 16.9 | 7.9 | 1.5 | 1.6 | 1.87 |
| Chuck James* | KCA | sp | 26 | 1 | 1 | 2 | 1 | 0 | 0 | 5 | 3 | 7.3 | 3.9 | 11.3 | 6.7 | 1.3 | 1.7 | 1.24 |
| Casey Janssen | HOU | mr | 26 | 1 | 0 | 2 | 2 | 3 | 0 | 0 | 2 | 11.4 | 2.1 | 14.0 | 6.2 | 0.7 | 3.0 | 1.50 |
| Casey Janssen | STL | mr | 26 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 9.5 | 2.2 | 12.1 | 5.1 | 0.3 | 2.3 | 1.31 |
| Casey Janssen |   | mr | 26 | 1 | 0 | 2 | 3 | 4 | 0 | 1 | 3 | 10.6 | 2.1 | 13.2 | 5.7 | 0.5 | 2.7 | 1.42 |
| Bobby Jenks | DET | cl | 27 | 3 | 0 | 1 | 1 | 6 | 0 | 1 | 2 | 8.5 | 2.5 | 11.2 | 7.7 | 0.2 | 3.1 | 1.23 |
| Jason Jennings | PIT | sp | 29 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2 | 31.5 | 4.5 | 36.0 | 4.5 | 4.5 | 1.0 | 4.00 |
| Ubaldo Jimenez | LAD | sp | 24 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.8 | 4.2 | 13.0 | 8.4 | 0.5 | 2.0 | 1.45 |
| Ubaldo Jimenez | CAL | sp | 24 | 5 | 3 | 2 | 2 | 6 | 0 | 1 | 1 | 6.7 | 4.1 | 11.1 | 6.5 | 0.6 | 1.6 | 1.20 |
| Ubaldo Jimenez |   | sp | 24 | 6 | 3 | 3 | 2 | 6 | 0 | 1 | 1 | 7.2 | 4.1 | 11.5 | 7.0 | 0.5 | 1.7 | 1.26 |
| Josh Johnson | MIL | sp | 24 | 1 | 1 | 0 | 0 | 0 | 0 | 3 | 0 | 14.0 | 4.7 | 18.6 | 4.2 | 0.5 | 0.9 | 2.07 |
| Randy Johnson* | KCA | sp | 44 | 1 | 2 | 0 | 7 | 0 | 0 | 1 | 0 | 8.3 | 3.2 | 12.9 | 13.7 | 1.0 | 4.3 | 1.28 |
| Tyler Johnson* | STL | mr | 27 | 2 | 1 | 0 | 0 | 3 | 0 | 1 | 0 | 6.9 | 3.2 | 10.1 | 7.1 | 0.7 | 2.2 | 1.12 |
| Todd Jones | CIN | cl | 40 | 0 | 2 | 1 | 0 | 1 | 0 | 1 | 6 | 8.6 | 2.5 | 11.0 | 4.4 | 1.0 | 1.8 | 1.23 |
| Jorge Julio | BAL | mr | 29 | 6 | 0 | 3 | 1 | 3 | 1 | 3 | 1 | 11.2 | 5.2 | 16.6 | 9.2 | 1.8 | 1.8 | 1.82 |
| Scott Kazmir* | CIN | sp | 24 | 7 | 1 | 2 | 5 | 7 | 0 | 3 | 2 | 9.2 | 5.1 | 14.9 | 12.2 | 1.0 | 2.4 | 1.59 |
| Scott Kazmir* | CLE | sp | 24 | 5 | 1 | 2 | 2 | 5 | 0 | 4 | 3 | 7.6 | 3.5 | 11.3 | 11.6 | 1.2 | 3.3 | 1.23 |
| Scott Kazmir* |   | sp | 24 | 12 | 2 | 4 | 7 | 12 | 0 | 7 | 5 | 8.4 | 4.2 | 12.9 | 11.9 | 1.1 | 2.8 | 1.40 |
| Kyle Kendrick | MIL | sp | 23 | 2 | 2 | 3 | 5 | 0 | 0 | 2 | 1 | 9.6 | 1.5 | 11.6 | 2.6 | 1.4 | 1.8 | 1.24 |
| Joe Kennedy* | LAD | mr | 29 | 0 | 1 | 0 | 1 | 2 | 0 | 0 | 0 | 9.6 | 1.9 | 12.2 | 1.3 | 1.9 | 0.7 | 1.29 |
| Logan Kensing | PIT | mr | 25 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 15.7 | 1.7 | 19.2 | 7.8 | 2.6 | 4.5 | 1.94 |
| Ray King* | NYM | mr | 34 | 2 | 1 | 2 | 3 | 0 | 1 | 0 | 1 | 13.8 | 4.6 | 19.2 | 4.6 | 1.3 | 1.0 | 2.04 |
| John Lackey | KCA | sp | 29 | 8 | 4 | 1 | 14 | 13 | 1 | 6 | 5 | 7.8 | 2.2 | 10.7 | 7.9 | 0.6 | 3.5 | 1.12 |
| Aaron Laffey* | HOU | sp | 23 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 10.6 | 1.2 | 11.8 | 4.0 | 0.3 | 3.3 | 1.31 |
| Aaron Laffey* | STL | sp | 23 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 10.1 | 2.4 | 13.0 | 5.8 | 0.0 | 2.4 | 1.39 |
| Aaron Laffey* |   | sp | 23 | 1 | 0 | 0 | 1 | 2 | 0 | 2 | 0 | 10.4 | 1.7 | 12.3 | 4.7 | 0.2 | 2.8 | 1.34 |
| John Lannan* | SFG | sp | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.5 | 11.3 | 24.8 | 2.3 | 4.5 | 0.2 | 2.75 |
| John Lannan* | WAS | sp | 23 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 1 | 10.3 | 6.8 | 17.9 | 3.2 | 0.8 | 0.5 | 1.90 |
| John Lannan* |   | sp | 23 | 1 | 1 | 0 | 2 | 1 | 0 | 0 | 1 | 10.8 | 7.4 | 18.9 | 3.0 | 1.3 | 0.4 | 2.02 |
| Brandon League | WAS | mr | 25 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 9.3 | 1.7 | 11.0 | 3.4 | 0.8 | 2.0 | 1.22 |
| Cliff Lee* | PHI | sp | 29 | 0 | 3 | 3 | 6 | 4 | 0 | 2 | 7 | 9.0 | 3.5 | 13.0 | 5.8 | 1.9 | 1.7 | 1.39 |
| Jon Lester* | HOU | sp | 24 | 3 | 1 | 1 | 3 | 1 | 0 | 2 | 6 | 10.1 | 3.3 | 13.9 | 6.6 | 1.4 | 2.0 | 1.49 |
| Brad Lidge | PHI | cl | 31 | 1 | 0 | 1 | 2 | 5 | 0 | 2 | 2 | 6.3 | 3.2 | 9.8 | 10.8 | 0.6 | 3.4 | 1.05 |
| Jon Lieber | PHI | sp | 38 | 10 | 3 | 1 | 2 | 2 | 1 | 3 | 4 | 10.3 | 2.4 | 12.9 | 5.3 | 0.6 | 2.2 | 1.41 |
| Ted Lilly* | SFG | sp | 32 | 17 | 4 | 5 | 6 | 7 | 0 | 7 | 7 | 9.6 | 2.7 | 12.6 | 7.3 | 1.6 | 2.7 | 1.37 |
| Tim Lincecum | WAS | sp | 24 | 6 | 3 | 2 | 1 | 2 | 0 | 5 | 5 | 7.6 | 3.8 | 11.5 | 8.6 | 1.2 | 2.2 | 1.28 |
| Matt Lindstrom | CAL | mr | 28 | 2 | 1 | 2 | 5 | 3 | 0 | 2 | 2 | 8.0 | 2.6 | 11.4 | 8.2 | 0.4 | 3.1 | 1.18 |
| Scott Linebrink | CLE | mr | 31 | 10 | 2 | 1 | 2 | 4 | 0 | 1 | 4 | 9.6 | 4.3 | 14.1 | 6.4 | 2.3 | 1.5 | 1.54 |
| Jesse Litsch | LAD | sp | 23 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 12.3 | 1.9 | 14.7 | 3.1 | 0.8 | 1.6 | 1.59 |
| Jesse Litsch | CAL | sp | 23 | 2 | 0 | 1 | 4 | 1 | 0 | 4 | 1 | 9.3 | 2.2 | 11.9 | 4.7 | 1.0 | 2.1 | 1.28 |
| Jesse Litsch |   | sp | 23 | 2 | 0 | 1 | 5 | 1 | 0 | 5 | 3 | 9.9 | 2.1 | 12.5 | 4.4 | 1.0 | 2.0 | 1.34 |
| Wes Littleton | LAD | mr | 25 | 2 | 0 | 1 | 3 | 1 | 0 | 3 | 0 | 9.0 | 5.3 | 14.9 | 4.9 | 1.4 | 0.9 | 1.59 |
| Kameron Loe | NYM | sp | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.6 | 4.4 | 10.9 | 8.8 | 0.0 | 2.0 | 1.22 |
| Adam Loewen* | NYM | sp | 24 | 0 | 0 | 1 | 3 | 3 | 1 | 0 | 0 | 8.3 | 8.1 | 17.2 | 6.3 | 0.3 | 0.8 | 1.82 |
| Boone Logan* | NYM | mr | 23 | 1 | 1 | 2 | 0 | 3 | 1 | 1 | 4 | 14.7 | 4.8 | 19.4 | 5.6 | 1.5 | 1.2 | 2.16 |
| Kyle Lohse | MIN | sp | 29 | 14 | 5 | 1 | 7 | 1 | 0 | 8 | 6 | 9.3 | 2.5 | 12.2 | 6.5 | 1.0 | 2.6 | 1.32 |
| Braden Looper | CAL | sp | 33 | 11 | 5 | 5 | 5 | 0 | 2 | 4 | 11 | 10.3 | 3.5 | 14.1 | 6.0 | 1.1 | 1.7 | 1.54 |
| Javier Lopez* | LAD | mr | 30 | 4 | 0 | 1 | 4 | 0 | 0 | 2 | 0 | 5.4 | 4.7 | 10.9 | 2.6 | 0.6 | 0.5 | 1.12 |
| Rodrigo Lopez | STL | sp | 32 | 3 | 3 | 3 | 1 | 0 | 0 | 3 | 1 | 10.4 | 2.3 | 12.8 | 4.5 | 1.5 | 2.0 | 1.41 |
| Derek Lowe | CWS | sp | 35 | 8 | 2 | 6 | 6 | 3 | 0 | 6 | 5 | 8.9 | 3.4 | 12.5 | 7.6 | 0.9 | 2.3 | 1.36 |
| Noah Lowry* | CAL | sp | 27 | 5 | 1 | 2 | 4 | 1 | 0 | 1 | 2 | 12.0 | 6.3 | 18.8 | 6.3 | 1.5 | 1.0 | 2.04 |
| Brandon Lyon | MIN | mr | 28 | 5 | 2 | 3 | 0 | 2 | 2 | 0 | 5 | 9.0 | 2.9 | 11.9 | 5.3 | 0.3 | 1.8 | 1.32 |
| Greg Maddux | BAL | sp | 42 | 28 | 3 | 2 | 4 | 2 | 0 | 6 | 4 | 10.5 | 1.6 | 12.3 | 5.0 | 0.7 | 3.0 | 1.35 |
| Ryan Madson | CAL | mr | 27 | 2 | 1 | 2 | 1 | 1 | 1 | 4 | 4 | 10.6 | 4.3 | 15.1 | 5.9 | 1.3 | 1.4 | 1.66 |
| Ron Mahay* | CAL | mr | 37 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 3 | 10.9 | 6.0 | 16.9 | 10.7 | 1.1 | 1.8 | 1.88 |
| Paul Maholm* | PHI | sp | 26 | 7 | 9 | 3 | 8 | 3 | 0 | 4 | 7 | 11.1 | 3.5 | 15.0 | 5.1 | 1.6 | 1.5 | 1.62 |
| John Maine | PHI | sp | 27 | 6 | 3 | 2 | 6 | 1 | 0 | 11 | 4 | 9.6 | 3.1 | 13.0 | 8.6 | 1.7 | 2.8 | 1.41 |
| Shaun Marcum | CHI | sp | 26 | 8 | 3 | 1 | 9 | 2 | 0 | 5 | 2 | 9.8 | 2.4 | 12.8 | 7.1 | 1.7 | 3.0 | 1.36 |
| Carlos Marmol | CHI | mr | 25 | 2 | 2 | 1 | 2 | 3 | 2 | 5 | 2 | 5.8 | 5.1 | 11.2 | 11.9 | 1.2 | 2.3 | 1.21 |
| Jason Marquis | HOU | sp | 29 | 13 | 8 | 9 | 14 | 4 | 0 | 4 | 7 | 8.1 | 3.0 | 11.7 | 5.0 | 0.6 | 1.7 | 1.23 |
| Sean Marshall* | NYM | sp | 25 | 5 | 2 | 4 | 1 | 4 | 0 | 3 | 3 | 11.1 | 3.3 | 14.5 | 5.6 | 1.5 | 1.7 | 1.60 |
| Damaso Marte* | MIL | mr | 33 | 1 | 2 | 1 | 1 | 0 | 1 | 2 | 0 | 8.7 | 3.1 | 12.0 | 9.9 | 1.0 | 3.2 | 1.31 |
| Pedro Martinez | NYA | sp | 36 | 2 | 1 | 0 | 1 | 2 | 0 | 1 | 0 | 14.3 | 1.3 | 16.0 | 10.1 | 0.0 | 8.0 | 1.73 |
| Daisuke Matsuzaka | DET | sp | 27 | 16 | 6 | 2 | 9 | 2 | 0 | 7 | 6 | 8.7 | 3.5 | 12.7 | 10.0 | 1.8 | 2.9 | 1.36 |
| Brandon McCarthy | DET | sp | 24 | 5 | 1 | 0 | 4 | 1 | 0 | 3 | 4 | 11.2 | 5.6 | 17.2 | 5.6 | 1.9 | 1.0 | 1.86 |
| Dustin McGowan | NYA | sp | 26 | 14 | 1 | 3 | 1 | 14 | 0 | 3 | 3 | 7.8 | 3.0 | 10.9 | 8.6 | 0.7 | 2.8 | 1.21 |
| Gil Meche | CHI | sp | 29 | 3 | 2 | 2 | 3 | 3 | 0 | 6 | 4 | 8.3 | 2.0 | 10.4 | 6.5 | 1.2 | 3.2 | 1.15 |
| Cla Meredith | DET | mr | 25 | 1 | 0 | 1 | 1 | 1 | 3 | 2 | 1 | 9.4 | 2.5 | 12.0 | 5.9 | 1.1 | 2.3 | 1.32 |
| Andrew Miller* | HOU | sp | 23 | 6 | 1 | 12 | 3 | 4 | 1 | 2 | 3 | 10.0 | 4.7 | 15.1 | 9.1 | 1.3 | 1.9 | 1.63 |
| Justin Miller | HOU | mr | 30 | 1 | 0 | 8 | 1 | 4 | 0 | 1 | 4 | 8.4 | 2.3 | 10.8 | 7.9 | 1.0 | 3.4 | 1.19 |
| Trever Miller* | BOS | mr | 35 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 3 | 13.0 | 5.4 | 18.9 | 11.9 | 0.5 | 2.2 | 2.04 |
| Kevin Millwood | BAL | sp | 33 | 16 | 7 | 2 | 1 | 4 | 0 | 4 | 8 | 8.5 | 3.0 | 11.6 | 6.2 | 0.9 | 2.1 | 1.29 |
| Zach Miner | KCA | mr | 26 | 3 | 4 | 0 | 1 | 1 | 0 | 1 | 0 | 5.4 | 3.4 | 8.9 | 5.9 | 0.2 | 1.7 | 0.98 |
| Sergio Mitre | PHI | sp | 27 | 15 | 5 | 4 | 13 | 6 | 0 | 9 | 6 | 11.0 | 2.9 | 14.8 | 4.7 | 0.9 | 1.6 | 1.54 |
| Brian Moehler | NYM | mr | 36 | 1 | 1 | 4 | 1 | 0 | 0 | 1 | 2 | 10.5 | 3.4 | 14.3 | 5.9 | 0.4 | 1.8 | 1.55 |
| Franklin Morales* | BOS | sp | 22 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 8.2 | 4.9 | 13.0 | 6.4 | 0.6 | 1.3 | 1.45 |
| Matt Morris | NYM | sp | 33 | 8 | 2 | 11 | 9 | 2 | 0 | 6 | 6 | 11.6 | 3.5 | 15.4 | 3.7 | 0.9 | 1.1 | 1.67 |
| Brandon Morrow | NYM | mr | 23 | 4 | 2 | 0 | 1 | 5 | 0 | 2 | 2 | 11.2 | 8.5 | 19.9 | 9.2 | 0.7 | 1.1 | 2.19 |
| Dustin Moseley | NYA | mr | 26 | 1 | 0 | 0 | 3 | 3 | 2 | 2 | 2 | 7.3 | 2.3 | 10.0 | 7.0 | 0.4 | 3.1 | 1.07 |
| Guillermo Mota | CLE | mr | 34 | 3 | 1 | 0 | 0 | 1 | 0 | 1 | 2 | 10.8 | 3.0 | 13.8 | 9.0 | 1.6 | 3.0 | 1.54 |
| Jamie Moyer* | BOS | sp | 45 | 11 | 3 | 8 | 4 | 0 | 0 | 7 | 5 | 11.4 | 3.4 | 15.0 | 6.8 | 1.5 | 2.0 | 1.64 |
| Peter Moylan | PIT | mr | 29 | 4 | 1 | 4 | 6 | 2 | 0 | 0 | 0 | 9.3 | 2.0 | 11.9 | 5.6 | 0.9 | 2.8 | 1.26 |
| Mike Mussina | CLE | sp | 39 | 19 | 0 | 3 | 5 | 2 | 0 | 3 | 6 | 11.2 | 1.8 | 13.3 | 6.3 | 0.8 | 3.6 | 1.44 |
| Brett Myers | LAD | cl | 27 | 3 | 1 | 0 | 6 | 5 | 0 | 3 | 1 | 6.9 | 4.0 | 11.7 | 10.3 | 0.5 | 2.6 | 1.21 |
| Joe Nathan | MIL | cl | 33 | 4 | 1 | 3 | 0 | 0 | 0 | 3 | 1 | 8.1 | 3.5 | 11.5 | 9.5 | 0.7 | 2.7 | 1.28 |
| Joe Nathan | MIN | cl | 33 | 7 | 1 | 3 | 1 | 0 | 0 | 1 | 1 | 8.0 | 3.3 | 11.7 | 9.7 | 0.0 | 2.9 | 1.26 |
| Joe Nathan |   | cl | 33 | 11 | 2 | 6 | 1 | 0 | 0 | 4 | 2 | 8.0 | 3.4 | 11.6 | 9.5 | 0.4 | 2.8 | 1.27 |
| Pat Neshek | CIN | mr | 27 | 3 | 0 | 1 | 2 | 0 | 0 | 0 | 4 | 9.2 | 2.7 | 12.4 | 12.1 | 1.6 | 4.4 | 1.32 |
| Pat Neshek | STL | mr | 27 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.1 | 2.5 | 7.6 | 11.8 | 1.6 | 4.6 | 0.85 |
| Pat Neshek |   | mr | 27 | 4 | 0 | 1 | 2 | 0 | 0 | 0 | 6 | 7.4 | 2.7 | 10.4 | 12.0 | 1.6 | 4.5 | 1.12 |
| Dustin Nippert | CWS | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 20.3 | 13.5 | 33.8 | 6.8 | 0.0 | 0.5 | 3.75 |
| Leo Nunez | CWS | mr | 24 | 1 | 0 | 0 | 0 | 1 | 0 | 2 | 2 | 9.4 | 3.7 | 13.2 | 9.4 | 1.0 | 2.5 | 1.46 |
| Eric O'Flaherty* | PHI | mr | 23 | 0 | 0 | 2 | 3 | 3 | 1 | 2 | 1 | 8.3 | 2.2 | 11.1 | 4.2 | 0.8 | 1.9 | 1.16 |
| Hideki Okajima* | CHI | mr | 32 | 2 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 8.6 | 1.5 | 10.1 | 9.4 | 1.6 | 6.4 | 1.12 |
| Darren Oliver* | BAL | mr | 37 | 4 | 2 | 0 | 1 | 0 | 1 | 1 | 1 | 7.4 | 4.0 | 11.6 | 6.5 | 0.8 | 1.6 | 1.27 |
| Scott Olsen* | MIL | sp | 24 | 0 | 0 | 2 | 0 | 5 | 0 | 1 | 4 | 14.0 | 3.6 | 17.7 | 5.9 | 1.9 | 1.6 | 1.96 |
| Scott Olsen* | WAS | sp | 24 | 4 | 4 | 1 | 0 | 6 | 0 | 5 | 3 | 10.1 | 5.7 | 15.8 | 6.6 | 0.9 | 1.1 | 1.76 |
| Scott Olsen* |   | sp | 24 | 4 | 4 | 3 | 0 | 11 | 0 | 6 | 7 | 11.5 | 5.0 | 16.5 | 6.3 | 1.3 | 1.3 | 1.83 |
| Garrett Olson* | WAS | sp | 24 | 3 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 15.2 | 8.1 | 24.2 | 6.5 | 2.5 | 0.8 | 2.59 |
| Ramon Ortiz | LAD | mr | 35 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 9.9 | 0.7 | 11.4 | 2.1 | 0.7 | 3.0 | 1.18 |
| Roy Oswalt | CWS | sp | 30 | 5 | 2 | 3 | 3 | 3 | 2 | 4 | 7 | 9.1 | 3.2 | 12.5 | 6.8 | 0.7 | 2.1 | 1.37 |
| Akinori Otsuka | NYA | mr | 36 | 2 | 0 | 1 | 2 | 1 | 1 | 0 | 2 | 7.0 | 3.0 | 10.7 | 10.4 | 0.4 | 3.5 | 1.11 |
| Micah Owings | MIN | sp | 25 | 11 | 2 | 4 | 15 | 2 | 0 | 5 | 3 | 9.2 | 3.5 | 13.7 | 8.0 | 1.5 | 2.3 | 1.41 |
| Vicente Padilla | BOS | sp | 30 | 2 | 0 | 1 | 6 | 1 | 0 | 3 | 2 | 12.1 | 5.1 | 18.0 | 6.4 | 1.9 | 1.3 | 1.91 |
| Vicente Padilla | MIN | sp | 30 | 4 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 14.0 | 2.1 | 16.5 | 5.9 | 0.5 | 2.9 | 1.78 |
| Vicente Padilla |   | sp | 30 | 6 | 0 | 1 | 8 | 1 | 0 | 3 | 3 | 12.8 | 3.9 | 17.4 | 6.2 | 1.4 | 1.6 | 1.86 |
| Jonathan Papelbon | NYA | cl | 27 | 4 | 3 | 1 | 5 | 0 | 0 | 2 | 2 | 6.2 | 2.6 | 9.6 | 12.8 | 1.6 | 4.9 | 0.98 |
| Chad Paronto | MIL | mr | 32 | 1 | 0 | 0 | 3 | 0 | 0 | 3 | 1 | 13.1 | 5.4 | 20.8 | 2.3 | 0.0 | 0.4 | 2.06 |
| John Patterson | CWS | sp | 30 | 2 | 0 | 1 | 0 | 2 | 0 | 2 | 2 | 8.7 | 4.5 | 13.2 | 4.2 | 0.3 | 0.9 | 1.46 |
| Jake Peavy | CHI | sp | 27 | 19 | 9 | 1 | 6 | 4 | 0 | 7 | 6 | 7.8 | 1.9 | 10.0 | 8.7 | 0.9 | 4.7 | 1.08 |
| Mike Pelfrey | MIL | sp | 24 | 1 | 0 | 4 | 3 | 6 | 0 | 1 | 3 | 10.5 | 5.8 | 16.8 | 6.6 | 0.8 | 1.1 | 1.81 |
| Tony Pena | STL | mr | 26 | 5 | 1 | 2 | 7 | 3 | 5 | 5 | 4 | 7.3 | 3.5 | 11.7 | 5.7 | 1.3 | 1.6 | 1.21 |
| Brad Penny | SFG | sp | 30 | 10 | 1 | 4 | 3 | 0 | 0 | 5 | 5 | 11.0 | 3.7 | 15.0 | 6.4 | 1.1 | 1.7 | 1.63 |
| Brad Penny | DET | sp | 30 | 1 | 0 | 0 | 1 | 2 | 0 | 3 | 3 | 9.1 | 3.9 | 13.1 | 4.8 | 1.2 | 1.2 | 1.44 |
| Brad Penny |   | sp | 30 | 11 | 1 | 4 | 4 | 2 | 0 | 8 | 8 | 10.2 | 3.8 | 14.2 | 5.8 | 1.2 | 1.5 | 1.56 |
| Joel Peralta | BAL | mr | 32 | 10 | 1 | 1 | 2 | 0 | 0 | 5 | 1 | 8.9 | 1.3 | 10.4 | 7.4 | 1.3 | 5.7 | 1.13 |
| Troy Percival | CHI | mr | 38 | 1 | 1 | 0 | 0 | 2 | 0 | 1 | 1 | 8.3 | 2.5 | 10.8 | 10.8 | 1.5 | 4.3 | 1.19 |
| Odalis Perez* | LAD | sp | 31 | 0 | 0 | 1 | 3 | 3 | 0 | 0 | 2 | 9.0 | 6.8 | 17.4 | 1.7 | 1.1 | 0.3 | 1.75 |
| Oliver Perez* | MIL | sp | 26 | 2 | 3 | 2 | 5 | 2 | 0 | 7 | 6 | 11.3 | 5.1 | 16.9 | 8.3 | 2.1 | 1.6 | 1.82 |
| Oliver Perez* | CLE | sp | 26 | 4 | 2 | 3 | 3 | 2 | 0 | 1 | 4 | 6.5 | 3.8 | 10.7 | 9.0 | 1.2 | 2.4 | 1.15 |
| Oliver Perez* |   | sp | 26 | 6 | 5 | 5 | 8 | 4 | 0 | 8 | 10 | 9.5 | 4.6 | 14.5 | 8.6 | 1.7 | 1.9 | 1.56 |
| Rafael Perez* | KCA | mr | 26 | 1 | 0 | 4 | 1 | 1 | 0 | 0 | 0 | 6.2 | 2.6 | 8.9 | 9.1 | 1.0 | 3.5 | 0.98 |
| Yusmeiro Petit | WAS | sp | 23 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 8.4 | 2.4 | 10.8 | 6.7 | 2.2 | 2.8 | 1.20 |
| Andy Pettitte* | PIT | sp | 36 | 7 | 1 | 6 | 4 | 3 | 0 | 10 | 5 | 8.7 | 2.3 | 11.2 | 6.5 | 0.7 | 2.8 | 1.22 |
| Joel Pineiro | MIN | mr | 29 | 8 | 2 | 4 | 0 | 2 | 0 | 3 | 2 | 11.5 | 3.9 | 15.4 | 4.3 | 2.3 | 1.1 | 1.71 |
| Renyel Pinto* | DET | mr | 25 | 0 | 0 | 1 | 3 | 0 | 0 | 2 | 1 | 8.5 | 5.6 | 14.7 | 10.3 | 0.4 | 1.8 | 1.57 |
| Scott Proctor | LAD | mr | 31 | 1 | 3 | 0 | 5 | 3 | 3 | 1 | 7 | 8.8 | 3.9 | 13.2 | 7.0 | 1.6 | 1.8 | 1.41 |
| J.J. Putz | CHI | cl | 31 | 2 | 2 | 3 | 0 | 6 | 0 | 1 | 0 | 4.4 | 2.4 | 6.8 | 8.6 | 0.8 | 3.6 | 0.76 |
| Chad Qualls | MIN | mr | 29 | 5 | 2 | 0 | 3 | 6 | 0 | 1 | 1 | 11.2 | 2.9 | 14.5 | 10.1 | 1.0 | 3.5 | 1.57 |
| Jon Rauch | LAD | mr | 29 | 5 | 1 | 2 | 0 | 3 | 0 | 3 | 3 | 8.0 | 3.7 | 11.7 | 6.5 | 0.6 | 1.7 | 1.30 |
| Jon Rauch | NYA | mr | 29 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 13.2 | 1.3 | 14.5 | 9.2 | 1.3 | 7.0 | 1.61 |
| Jon Rauch |   | mr | 29 | 6 | 1 | 2 | 0 | 3 | 0 | 3 | 3 | 8.8 | 3.4 | 12.1 | 6.9 | 0.7 | 2.1 | 1.35 |
| Chris Ray | DET | cl | 26 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 10.0 | 5.4 | 15.7 | 8.1 | 1.3 | 1.5 | 1.71 |
| Tim Redding | STL | sp | 30 | 1 | 1 | 0 | 7 | 1 | 3 | 4 | 4 | 12.5 | 5.4 | 18.8 | 6.3 | 1.2 | 1.2 | 1.99 |
| Al Reyes | CIN | cl | 38 | 1 | 0 | 0 | 4 | 1 | 0 | 0 | 1 | 7.8 | 4.2 | 12.6 | 8.7 | 1.4 | 2.1 | 1.34 |
| Anthony Reyes | MIN | sp | 26 | 2 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 10.7 | 5.2 | 16.8 | 7.9 | 2.4 | 1.5 | 1.78 |
| Jo-Jo Reyes* | WAS | sp | 23 | 0 | 1 | 0 | 0 | 1 | 0 | 2 | 1 | 12.3 | 6.4 | 18.7 | 4.6 | 2.3 | 0.7 | 2.08 |
| John Rheinecker* | NYM | mr | 29 | 0 | 2 | 4 | 1 | 2 | 1 | 2 | 1 | 11.1 | 4.8 | 16.1 | 6.0 | 1.8 | 1.3 | 1.76 |
| Juan Rincon | STL | mr | 29 | 0 | 0 | 2 | 2 | 1 | 0 | 0 | 1 | 8.0 | 2.6 | 11.0 | 6.5 | 1.5 | 2.5 | 1.18 |
| David Riske | CAL | mr | 31 | 5 | 3 | 5 | 1 | 0 | 0 | 2 | 1 | 8.8 | 3.2 | 12.1 | 5.7 | 0.4 | 1.8 | 1.33 |
| Mariano Rivera | NYA | cl | 38 | 0 | 3 | 0 | 5 | 3 | 0 | 1 | 4 | 7.9 | 2.3 | 10.9 | 8.8 | 0.3 | 3.9 | 1.13 |
| Saul Rivera | CWS | mr | 30 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 9.3 | 3.5 | 13.2 | 7.7 | 0.3 | 2.2 | 1.43 |
| Nate Robertson* | HOU | sp | 30 | 11 | 4 | 5 | 2 | 6 | 1 | 11 | 9 | 12.0 | 3.5 | 15.6 | 5.8 | 0.6 | 1.6 | 1.73 |
| Fernando Rodney | CHI | mr | 31 | 3 | 1 | 0 | 3 | 3 | 0 | 1 | 0 | 7.5 | 3.3 | 11.4 | 9.1 | 1.5 | 2.8 | 1.20 |
| Francisco Rodriguez | SFG | cl | 26 | 7 | 1 | 1 | 0 | 1 | 2 | 6 | 3 | 7.8 | 3.8 | 11.6 | 11.9 | 1.0 | 3.1 | 1.29 |
| Wandy Rodriguez* | LAD | sp | 29 | 7 | 4 | 2 | 11 | 4 | 0 | 7 | 7 | 9.0 | 2.4 | 11.9 | 7.5 | 0.9 | 3.2 | 1.26 |
| Kenny Rogers* | CHI | sp | 43 | 2 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 8.9 | 3.0 | 12.1 | 5.2 | 0.8 | 1.7 | 1.32 |
| J.C. Romero* | CLE | mr | 32 | 4 | 1 | 1 | 0 | 6 | 0 | 3 | 0 | 7.6 | 6.0 | 13.6 | 8.1 | 0.9 | 1.4 | 1.51 |
| Ryan Rowland-Smith* | WAS | mr | 25 | 1 | 0 | 2 | 2 | 0 | 0 | 2 | 1 | 8.7 | 5.6 | 14.8 | 8.7 | 0.8 | 1.6 | 1.59 |
| C.C. Sabathia* | NYA | sp | 27 | 3 | 1 | 0 | 5 | 0 | 0 | 6 | 10 | 10.0 | 1.4 | 11.6 | 8.4 | 1.0 | 5.9 | 1.27 |
| Takashi Saito | SFG | cl | 38 | 2 | 0 | 2 | 2 | 0 | 0 | 1 | 3 | 6.1 | 2.3 | 8.7 | 11.0 | 1.6 | 4.8 | 0.93 |
| Juan Salas | NYM | mr | 29 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 1 | 8.0 | 1.7 | 11.1 | 7.3 | 2.4 | 4.2 | 1.08 |
| Chris Sampson | BOS | sp | 30 | 1 | 1 | 5 | 5 | 3 | 0 | 3 | 6 | 10.5 | 3.7 | 14.8 | 4.3 | 1.7 | 1.2 | 1.58 |
| Anibal Sanchez | CAL | sp | 24 | 3 | 0 | 1 | 1 | 2 | 1 | 0 | 2 | 13.9 | 5.2 | 19.5 | 4.0 | 0.4 | 0.8 | 2.12 |
| Jonathan Sanchez* | HOU | mr | 25 | 3 | 2 | 6 | 0 | 3 | 0 | 1 | 2 | 15.5 | 5.4 | 21.0 | 10.7 | 1.2 | 2.0 | 2.33 |
| Ervin Santana | HOU | sp | 25 | 6 | 2 | 4 | 7 | 3 | 0 | 5 | 5 | 11.2 | 3.5 | 15.1 | 7.3 | 1.6 | 2.1 | 1.63 |
| Johan Santana* | KCA | sp | 29 | 4 | 2 | 2 | 2 | 4 | 1 | 3 | 2 | 7.0 | 2.0 | 9.1 | 10.2 | 1.6 | 5.1 | 1.00 |
| Joe Saunders* | PHI | sp | 27 | 3 | 5 | 0 | 4 | 2 | 0 | 4 | 6 | 11.9 | 3.1 | 15.3 | 5.5 | 0.7 | 1.8 | 1.66 |
| Curt Schilling | BAL | sp | 41 | 5 | 4 | 4 | 6 | 0 | 0 | 6 | 2 | 11.1 | 1.6 | 13.1 | 6.8 | 1.3 | 4.3 | 1.41 |
| Scott Schoeneweis* | BOS | mr | 34 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6.0 | 3.0 | 9.0 | 7.5 | 0.0 | 2.5 | 1.00 |
| Chris Schroder | CLE | mr | 29 | 4 | 2 | 4 | 1 | 1 | 1 | 2 | 2 | 14.0 | 4.7 | 18.9 | 9.9 | 0.9 | 2.1 | 2.08 |
| Rudy Seanez | BOS | mr | 39 | 2 | 0 | 3 | 3 | 2 | 0 | 1 | 2 | 8.9 | 4.8 | 14.2 | 9.6 | 1.7 | 2.0 | 1.52 |
| Bobby Seay* | DET | mr | 30 | 1 | 0 | 2 | 3 | 0 | 0 | 1 | 3 | 8.5 | 3.5 | 12.6 | 9.3 | 0.2 | 2.6 | 1.33 |
| Ben Sheets | KCA | sp | 29 | 11 | 4 | 0 | 3 | 2 | 0 | 4 | 1 | 8.3 | 2.6 | 11.1 | 8.2 | 0.6 | 3.2 | 1.21 |
| George Sherrill* | CHI | mr | 31 | 2 | 0 | 4 | 1 | 1 | 0 | 2 | 0 | 9.1 | 4.0 | 13.3 | 9.8 | 1.2 | 2.5 | 1.45 |
| James Shields | CWS | sp | 26 | 3 | 3 | 3 | 6 | 6 | 0 | 3 | 4 | 8.6 | 1.9 | 10.8 | 10.1 | 1.0 | 5.4 | 1.16 |
| Scot Shields | PHI | mr | 32 | 5 | 2 | 2 | 6 | 2 | 0 | 2 | 4 | 6.6 | 3.3 | 10.6 | 7.6 | 0.8 | 2.3 | 1.10 |
| Brian Shouse* | DET | mr | 39 | 1 | 1 | 0 | 5 | 0 | 1 | 1 | 1 | 10.4 | 2.5 | 14.3 | 6.6 | 0.3 | 2.6 | 1.44 |
| Carlos Silva | BOS | sp | 29 | 6 | 2 | 8 | 5 | 2 | 1 | 2 | 5 | 12.4 | 3.0 | 15.8 | 5.2 | 1.2 | 1.7 | 1.71 |
| Carlos Silva | MIN | sp | 29 | 6 | 1 | 0 | 1 | 2 | 0 | 2 | 0 | 9.8 | 1.5 | 11.4 | 3.9 | 0.9 | 2.7 | 1.25 |
| Carlos Silva |   | sp | 29 | 12 | 3 | 8 | 6 | 4 | 1 | 4 | 5 | 11.3 | 2.3 | 13.9 | 4.6 | 1.1 | 2.0 | 1.51 |
| Doug Slaten* | NYM | mr | 28 | 0 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 14.2 | 5.9 | 20.1 | 4.6 | 2.3 | 0.8 | 2.24 |
| Kevin Slowey | BOS | sp | 24 | 3 | 0 | 8 | 1 | 4 | 0 | 2 | 0 | 9.5 | 2.5 | 12.2 | 7.4 | 2.7 | 2.9 | 1.34 |
| Joe Smith | CIN | mr | 24 | 4 | 1 | 0 | 6 | 2 | 0 | 4 | 1 | 10.9 | 4.0 | 16.1 | 9.6 | 0.6 | 2.4 | 1.65 |
| John Smoltz | STL | sp | 41 | 14 | 5 | 4 | 4 | 7 | 0 | 6 | 3 | 9.1 | 2.2 | 11.5 | 10.4 | 1.3 | 4.7 | 1.25 |
| Ian Snell | MIL | sp | 26 | 6 | 0 | 2 | 2 | 7 | 0 | 4 | 5 | 10.0 | 2.9 | 13.0 | 7.0 | 0.8 | 2.4 | 1.42 |
| Ian Snell | HOU | sp | 26 | 3 | 6 | 6 | 7 | 1 | 0 | 5 | 2 | 10.1 | 3.0 | 13.8 | 7.1 | 1.0 | 2.3 | 1.47 |
| Ian Snell |   | sp | 26 | 9 | 6 | 8 | 9 | 8 | 0 | 9 | 7 | 10.1 | 3.0 | 13.5 | 7.0 | 0.9 | 2.4 | 1.45 |
| Kyle Snyder | BOS | mr | 30 | 1 | 3 | 2 | 3 | 3 | 0 | 1 | 2 | 6.3 | 4.5 | 11.3 | 6.6 | 2.1 | 1.5 | 1.20 |
| Andy Sonnanstine | CIN | sp | 25 | 2 | 3 | 2 | 9 | 2 | 0 | 1 | 5 | 12.7 | 1.9 | 15.3 | 6.8 | 1.6 | 3.6 | 1.63 |
| Joakim Soria | KCA | cl | 24 | 0 | 0 | 0 | 1 | 2 | 0 | 0 | 3 | 7.4 | 1.9 | 9.5 | 9.6 | 0.6 | 5.1 | 1.04 |
| Rafael Soriano | KCA | mr | 28 | 3 | 3 | 2 | 0 | 0 | 0 | 1 | 0 | 6.8 | 1.9 | 8.7 | 8.2 | 1.2 | 4.4 | 0.97 |
| Jorge Sosa | SFG | mr | 31 | 6 | 2 | 6 | 0 | 0 | 0 | 4 | 1 | 12.9 | 5.4 | 18.3 | 5.0 | 0.9 | 0.9 | 2.03 |
| Jeremy Sowers* | NYM | sp | 25 | 6 | 3 | 4 | 4 | 5 | 0 | 3 | 3 | 12.4 | 2.8 | 15.7 | 4.4 | 2.1 | 1.6 | 1.69 |
| Jeremy Sowers* | STL | sp | 25 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 21.3 | 0.0 | 22.7 | 2.8 | 4.3 | 99.0 | 2.37 |
| Jeremy Sowers* |   | sp | 25 | 7 | 3 | 4 | 5 | 5 | 0 | 3 | 3 | 13.1 | 2.6 | 16.3 | 4.3 | 2.3 | 1.7 | 1.75 |
| Justin Speier | SFG | mr | 34 | 1 | 1 | 0 | 4 | 2 | 0 | 4 | 1 | 8.3 | 1.4 | 10.4 | 6.7 | 1.4 | 4.6 | 1.08 |
| Russ Springer | BAL | mr | 39 | 3 | 1 | 0 | 5 | 0 | 0 | 0 | 3 | 6.5 | 2.8 | 10.1 | 9.8 | 0.7 | 3.6 | 1.03 |
| Huston Street | CWS | cl | 24 | 5 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 7.5 | 2.2 | 9.9 | 10.5 | 1.8 | 4.7 | 1.07 |
| Jeff Suppan | SFG | sp | 33 | 10 | 3 | 3 | 12 | 8 | 0 | 3 | 6 | 11.1 | 2.9 | 14.6 | 5.2 | 0.9 | 1.8 | 1.55 |
| Brian Tallet* | SFG | mr | 30 | 3 | 1 | 3 | 3 | 4 | 0 | 1 | 1 | 8.5 | 3.3 | 12.2 | 7.5 | 0.7 | 2.3 | 1.31 |
| Taylor Tankersley* | MIL | mr | 25 | 2 | 0 | 2 | 1 | 2 | 0 | 3 | 4 | 10.0 | 5.3 | 15.5 | 9.8 | 1.9 | 1.9 | 1.70 |
| Jack Taschner* | LAD | mr | 30 | 5 | 2 | 0 | 1 | 2 | 1 | 0 | 5 | 10.1 | 7.0 | 17.3 | 9.7 | 1.3 | 1.4 | 1.90 |
| Julian Tavarez | MIL | sp | 35 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 12.0 | 1.9 | 13.9 | 6.1 | 0.8 | 3.2 | 1.55 |
| Brad Thompson | LAD | mr | 26 | 2 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 15.1 | 3.2 | 20.6 | 4.8 | 1.6 | 1.5 | 2.03 |
| Matt Thornton* | CHI | mr | 31 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5.1 | 0.0 | 6.8 | 11.8 | 0.0 | 99.0 | 0.56 |
| Mike Timlin | DET | mr | 42 | 3 | 0 | 1 | 3 | 1 | 0 | 1 | 4 | 7.7 | 1.5 | 9.7 | 5.3 | 0.7 | 3.4 | 1.03 |
| Josh Towers | CIN | sp | 31 | 5 | 2 | 3 | 7 | 0 | 0 | 2 | 2 | 9.9 | 1.6 | 12.2 | 6.0 | 1.4 | 3.8 | 1.28 |
| Steve Trachsel | MIL | sp | 37 | 2 | 2 | 0 | 3 | 2 | 3 | 5 | 5 | 12.8 | 5.9 | 19.2 | 3.7 | 1.6 | 0.6 | 2.07 |
| Derrick Turnbow | NYA | mr | 30 | 1 | 0 | 0 | 1 | 3 | 0 | 1 | 0 | 7.0 | 4.8 | 12.1 | 10.8 | 1.3 | 2.2 | 1.32 |
| Jose Valverde | CWS | cl | 28 | 4 | 2 | 1 | 3 | 0 | 0 | 2 | 0 | 7.0 | 3.4 | 10.9 | 11.5 | 1.2 | 3.3 | 1.17 |
| Rick VandenHurk | HOU | sp | 23 | 5 | 1 | 4 | 4 | 7 | 0 | 2 | 3 | 11.7 | 4.9 | 17.1 | 9.5 | 2.3 | 1.9 | 1.84 |
| Claudio Vargas | BAL | sp | 30 | 15 | 1 | 5 | 2 | 1 | 0 | 3 | 4 | 9.8 | 4.8 | 14.8 | 7.3 | 1.4 | 1.5 | 1.63 |
| Javier Vazquez | CWS | sp | 31 | 1 | 4 | 1 | 7 | 3 | 0 | 7 | 2 | 7.6 | 2.8 | 10.8 | 9.9 | 1.1 | 3.5 | 1.16 |
| Justin Verlander | STL | sp | 25 | 4 | 9 | 2 | 15 | 15 | 3 | 3 | 4 | 8.3 | 2.8 | 11.8 | 7.4 | 1.4 | 2.6 | 1.24 |
| Carlos Villanueva | STL | mr | 24 | 4 | 6 | 2 | 9 | 4 | 0 | 4 | 3 | 10.0 | 4.2 | 14.9 | 7.9 | 1.7 | 1.9 | 1.57 |
| Oscar Villarreal | PIT | mr | 26 | 0 | 1 | 4 | 11 | 11 | 0 | 2 | 4 | 9.5 | 2.4 | 13.3 | 7.0 | 1.2 | 2.9 | 1.33 |
| Ron Villone* | KCA | mr | 38 | 0 | 0 | 0 | 3 | 4 | 0 | 1 | 2 | 7.9 | 3.1 | 11.7 | 7.9 | 0.7 | 2.5 | 1.22 |
| Luis Vizcaino | MIN | mr | 33 | 2 | 1 | 2 | 0 | 0 | 0 | 1 | 4 | 7.8 | 4.3 | 12.1 | 6.5 | 1.0 | 1.5 | 1.34 |
| Billy Wagner* | NYA | cl | 36 | 1 | 0 | 2 | 1 | 3 | 0 | 1 | 1 | 8.3 | 2.9 | 11.3 | 12.0 | 1.2 | 4.2 | 1.24 |
| Adam Wainwright | PIT | sp | 26 | 6 | 5 | 1 | 12 | 3 | 0 | 5 | 12 | 10.5 | 2.5 | 13.5 | 6.7 | 0.6 | 2.6 | 1.44 |
| Tim Wakefield | CLE | sp | 41 | 12 | 5 | 1 | 1 | 3 | 0 | 6 | 2 | 9.7 | 3.2 | 13.0 | 4.9 | 1.3 | 1.5 | 1.44 |
| Tim Wakefield | MIN | sp | 41 | 7 | 0 | 1 | 3 | 5 | 0 | 2 | 2 | 9.5 | 2.8 | 12.6 | 5.6 | 1.5 | 2.0 | 1.37 |
| Tim Wakefield |   | sp | 41 | 19 | 5 | 2 | 4 | 8 | 0 | 8 | 4 | 9.6 | 3.0 | 12.9 | 5.2 | 1.4 | 1.7 | 1.41 |
| Jamie Walker* | BOS | mr | 36 | 3 | 0 | 3 | 3 | 3 | 0 | 3 | 2 | 9.1 | 3.2 | 12.7 | 5.4 | 0.6 | 1.7 | 1.36 |
| Chien-Ming Wang | CLE | sp | 28 | 13 | 1 | 4 | 6 | 7 | 1 | 2 | 6 | 8.2 | 2.9 | 11.4 | 4.6 | 0.5 | 1.6 | 1.23 |
| Jarrod Washburn* | BOS | sp | 33 | 8 | 2 | 6 | 5 | 2 | 2 | 3 | 5 | 10.9 | 3.3 | 14.5 | 5.9 | 1.9 | 1.8 | 1.58 |
| David Weathers | CIN | cl | 38 | 2 | 0 | 2 | 4 | 3 | 0 | 1 | 4 | 8.6 | 3.6 | 12.8 | 3.8 | 0.7 | 1.0 | 1.36 |
| Jered Weaver | PHI | sp | 25 | 12 | 7 | 3 | 4 | 4 | 0 | 6 | 6 | 8.4 | 2.3 | 10.9 | 6.8 | 1.1 | 3.0 | 1.19 |
| Brandon Webb | SFG | sp | 29 | 10 | 0 | 4 | 4 | 0 | 0 | 5 | 4 | 9.7 | 2.4 | 12.4 | 8.7 | 0.7 | 3.7 | 1.34 |
| Brandon Webb | WAS | sp | 29 | 7 | 2 | 1 | 1 | 1 | 0 | 1 | 1 | 10.1 | 3.4 | 13.6 | 8.0 | 1.6 | 2.4 | 1.50 |
| Brandon Webb |   | sp | 29 | 17 | 2 | 5 | 5 | 1 | 0 | 6 | 5 | 9.9 | 2.8 | 12.9 | 8.4 | 1.1 | 3.0 | 1.41 |
| Todd Wellemeyer | BOS | mr | 29 | 7 | 4 | 4 | 4 | 1 | 0 | 0 | 4 | 9.9 | 4.7 | 15.2 | 7.8 | 2.0 | 1.6 | 1.63 |
| Kip Wells | HOU | sp | 31 | 8 | 1 | 1 | 5 | 0 | 0 | 1 | 0 | 10.4 | 3.3 | 14.3 | 6.6 | 1.2 | 2.0 | 1.53 |
| Jake Westbrook | MIN | sp | 30 | 13 | 2 | 2 | 6 | 1 | 0 | 5 | 5 | 9.7 | 2.6 | 12.6 | 5.7 | 1.3 | 2.2 | 1.36 |
| Dan Wheeler | CIN | mr | 30 | 3 | 0 | 1 | 5 | 2 | 0 | 2 | 2 | 10.2 | 1.9 | 12.8 | 9.9 | 1.5 | 5.1 | 1.35 |
| Bob Wickman | SFG | cl | 39 | 6 | 0 | 3 | 3 | 2 | 0 | 0 | 2 | 11.1 | 4.7 | 16.9 | 4.0 | 1.0 | 0.9 | 1.76 |
| Woody Williams | BOS | sp | 41 | 2 | 0 | 4 | 6 | 0 | 5 | 1 | 4 | 12.5 | 3.8 | 17.3 | 5.7 | 1.8 | 1.5 | 1.81 |
| Dontrelle Willis* | CLE | sp | 26 | 4 | 4 | 2 | 18 | 12 | 0 | 11 | 1 | 11.6 | 4.3 | 16.8 | 6.8 | 1.3 | 1.6 | 1.77 |
| C.J. Wilson* | CIN | mr | 27 | 2 | 2 | 2 | 6 | 1 | 0 | 1 | 1 | 7.2 | 5.0 | 13.0 | 6.8 | 0.7 | 1.4 | 1.35 |
| Matt Wise | MIL | mr | 32 | 3 | 0 | 4 | 1 | 0 | 0 | 3 | 0 | 10.6 | 5.5 | 16.4 | 6.7 | 1.2 | 1.2 | 1.78 |
| Randy Wolf* | HOU | sp | 31 | 2 | 0 | 2 | 7 | 3 | 0 | 4 | 1 | 9.9 | 3.2 | 13.8 | 8.1 | 1.6 | 2.5 | 1.46 |
| Brian Wolfe | DET | mr | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 9.0 | 2.0 | 11.0 | 4.3 | 2.0 | 2.2 | 1.22 |
| Kerry Wood | BOS | mr | 31 | 0 | 1 | 2 | 0 | 2 | 0 | 1 | 1 | 5.2 | 6.9 | 12.1 | 6.0 | 0.8 | 0.9 | 1.34 |
| Jamey Wright | MIL | mr | 33 | 2 | 1 | 8 | 1 | 3 | 0 | 3 | 2 | 7.6 | 5.0 | 12.7 | 4.7 | 0.8 | 0.9 | 1.39 |
| Michael Wuertz | LAD | mr | 29 | 4 | 1 | 0 | 2 | 8 | 0 | 2 | 8 | 10.2 | 3.2 | 13.6 | 10.4 | 1.0 | 3.2 | 1.49 |
| Tyler Yates | NYM | mr | 30 | 2 | 0 | 2 | 2 | 0 | 0 | 0 | 5 | 8.4 | 5.7 | 14.6 | 8.4 | 0.3 | 1.5 | 1.56 |
| Chris Young | CWS | sp | 29 | 10 | 6 | 2 | 3 | 3 | 4 | 7 | 13 | 6.9 | 4.5 | 11.5 | 8.7 | 0.5 | 2.0 | 1.26 |
| Carlos Zambrano | CAL | sp | 27 | 5 | 2 | 4 | 13 | 2 | 0 | 9 | 6 | 8.7 | 4.6 | 13.9 | 7.5 | 0.8 | 1.6 | 1.48 |
| Barry Zito* | PIT | sp | 30 | 2 | 1 | 4 | 2 | 4 | 0 | 2 | 7 | 8.7 | 2.9 | 11.7 | 6.0 | 0.9 | 2.1 | 1.29 |
| Joel Zumaya | DET | mr | 23 | 3 | 1 | 1 | 1 | 2 | 0 | 1 | 1 | 6.6 | 5.0 | 11.8 | 9.4 | 0.8 | 1.9 | 1.28 |
| Analytical |
| Name | Team | P | Age | OPS | BIP | IPAVG | TBW | TBW/BF | TBWH | TBWH/BF | RC | RC27 | RCERA | CERA |
| Jeremy Accardo | CHI | cl | 26 | .792 | 170 | .324 | 117 | .464 | 121 | .480 | 37.0 | 6.1 | 5.55 | 5.76 |
| Jeremy Affeldt* | CWS | mr | 29 | .721 | 135 | .304 | 101 | .447 | 104 | .460 | 24.3 | 4.3 | 3.83 | 4.47 |
| Bronson Arroyo | SFG | sp | 31 | .855 | 584 | .349 | 415 | .511 | 427 | .526 | 133.0 | 6.7 | 6.11 | 5.85 |
| Luis Ayala | CWS | mr | 30 | .835 | 56 | .268 | 46 | .541 | 46 | .541 | 12.8 | 6.3 | 5.47 | 6.27 |
| Cha Seung Baek | NYM | sp | 28 | .874 | 252 | .377 | 162 | .505 | 166 | .517 | 56.8 | 7.5 | 6.97 | 6.09 |
| Homer Bailey | HOU | sp | 22 | .791 | 150 | .307 | 96 | .475 | 98 | .485 | 25.1 | 4.9 | 4.58 | 5.21 |
| Scott Baker | MIL | sp | 26 | .904 | 396 | .336 | 293 | .557 | 297 | .565 | 89.7 | 6.8 | 6.26 | 6.45 |
| John Bale* | SFG | mr | 34 | .530 | 64 | .344 | 29 | .284 | 30 | .294 | 6.4 | 2.2 | 2.03 | 2.21 |
| Brian Bannister | HOU | sp | 27 | .711 | 544 | .272 | 285 | .423 | 291 | .432 | 73.7 | 4.1 | 3.79 | 3.54 |
| Miguel Batista | PIT | sp | 37 | .713 | 234 | .299 | 148 | .437 | 151 | .445 | 39.1 | 4.5 | 4.08 | 3.85 |
| Josh Beckett | WAS | sp | 28 | .691 | 531 | .294 | 341 | .425 | 346 | .431 | 87.1 | 4.1 | 3.69 | 3.32 |
| Erik Bedard* | HOU | sp | 29 | .670 | 243 | .305 | 163 | .407 | 169 | .423 | 40.0 | 3.7 | 3.40 | 3.51 |
| Erik Bedard* | STL | sp | 29 | .755 | 197 | .330 | 157 | .471 | 157 | .471 | 41.9 | 4.8 | 4.33 | 4.44 |
| Erik Bedard* |   | sp | 29 | .709 | 440 | .316 | 320 | .437 | 326 | .445 | 81.7 | 4.2 | 3.81 | 3.93 |
| Joe Beimel* | MIN | mr | 31 | .642 | 193 | .295 | 102 | .381 | 104 | .388 | 24.0 | 3.4 | 3.00 | 3.03 |
| Matt Belisle | SFG | sp | 28 | .955 | 186 | .344 | 145 | .571 | 149 | .587 | 49.2 | 8.0 | 7.25 | 7.38 |
| Heath Bell | KCA | mr | 30 | .600 | 196 | .260 | 120 | .372 | 123 | .381 | 25.3 | 2.8 | 2.52 | 2.49 |
| Joaquin Benoit | SFG | mr | 30 | .817 | 209 | .311 | 170 | .512 | 173 | .521 | 48.1 | 5.6 | 5.17 | 4.76 |
| Jason Bergmann | SFG | sp | 26 | .848 | 111 | .324 | 91 | .535 | 92 | .541 | 27.5 | 6.9 | 6.32 | 6.24 |
| Jason Bergmann | WAS | sp | 26 | .939 | 142 | .268 | 155 | .630 | 155 | .630 | 45.7 | 7.5 | 6.86 | 6.59 |
| Jason Bergmann |   | sp | 26 | .902 | 253 | .292 | 246 | .591 | 247 | .594 | 73.6 | 7.3 | 6.68 | 6.48 |
| Rafael Betancourt | BOS | mr | 33 | .576 | 90 | .278 | 45 | .331 | 47 | .346 | 10.9 | 2.9 | 2.65 | 2.48 |
| Rafael Betancourt | MIN | mr | 33 | .603 | 101 | .277 | 58 | .379 | 58 | .379 | 13.3 | 3.0 | 2.73 | 1.88 |
| Rafael Betancourt |   | mr | 33 | .591 | 191 | .277 | 103 | .356 | 105 | .363 | 24.4 | 3.0 | 2.72 | 2.15 |
| Chad Billingsley | CLE | mr | 23 | .705 | 391 | .269 | 262 | .445 | 265 | .450 | 66.9 | 4.4 | 3.99 | 3.90 |
| Joe Blanton | DET | sp | 27 | .839 | 587 | .332 | 391 | .503 | 395 | .508 | 119.8 | 6.2 | 5.60 | 5.71 |
| Jeremy Bonderman | DET | sp | 25 | .769 | 428 | .334 | 294 | .469 | 296 | .472 | 81.0 | 5.0 | 4.45 | 4.45 |
| Boof Bonser | CIN | sp | 26 | .871 | 517 | .302 | 419 | .546 | 428 | .557 | 124.0 | 6.4 | 5.89 | 5.95 |
| Dave Borkowski | BOS | mr | 31 | .905 | 25 | .240 | 20 | .588 | 20 | .588 | 5.6 | 6.6 | 5.67 | 5.60 |
| Joe Borowski | BAL | cl | 37 | .845 | 142 | .352 | 117 | .525 | 119 | .534 | 35.5 | 6.2 | 5.61 | 5.10 |
| Micah Bowie* | CWS | mr | 33 | .577 | 91 | .297 | 46 | .333 | 47 | .341 | 9.7 | 2.5 | 2.19 | 2.13 |
| Dallas Braden* | WAS | sp | 24 | .941 | 216 | .352 | 180 | .579 | 182 | .585 | 62.8 | 8.8 | 7.91 | 7.37 |
| Chad Bradford | BAL | mr | 33 | .834 | 183 | .328 | 103 | .454 | 111 | .489 | 33.9 | 6.1 | 5.50 | 5.85 |
| Doug Brocail | PIT | mr | 41 | .784 | 244 | .270 | 153 | .483 | 157 | .495 | 42.6 | 5.2 | 4.75 | 4.44 |
| Andrew Brown | LAD | mr | 27 | .745 | 120 | .342 | 80 | .455 | 80 | .455 | 20.6 | 4.4 | 3.94 | 3.58 |
| Jonathan Broxton | KCA | mr | 24 | .680 | 175 | .331 | 114 | .415 | 116 | .422 | 27.7 | 3.7 | 3.33 | 3.09 |
| Brian Bruney | WAS | mr | 26 | 1.072 | 113 | .372 | 123 | .661 | 126 | .677 | 43.5 | 11.1 | 10.16 | 10.58 |
| Taylor Buchholz | BAL | mr | 26 | .730 | 254 | .350 | 133 | .407 | 136 | .416 | 37.9 | 4.5 | 4.03 | 4.16 |
| Mark Buehrle* | CIN | sp | 29 | .705 | 284 | .268 | 162 | .430 | 165 | .438 | 41.6 | 4.2 | 3.82 | 3.76 |
| Mark Buehrle* | CLE | sp | 29 | .744 | 319 | .298 | 200 | .450 | 204 | .459 | 53.5 | 4.6 | 4.13 | 4.08 |
| Mark Buehrle* |   | sp | 29 | .726 | 603 | .284 | 362 | .441 | 369 | .449 | 95.1 | 4.4 | 3.98 | 3.93 |
| Ambiorix Burgos | MIL | mr | 24 | .525 | 69 | .159 | 37 | .319 | 41 | .353 | 7.6 | 2.3 | 2.12 | 1.79 |
| A.J. Burnett | MIL | sp | 31 | .678 | 227 | .291 | 145 | .417 | 148 | .425 | 33.6 | 3.4 | 3.14 | 2.96 |
| A.J. Burnett | NYA | sp | 31 | .678 | 221 | .294 | 134 | .406 | 137 | .415 | 34.4 | 4.0 | 3.61 | 3.90 |
| A.J. Burnett |   | sp | 31 | .679 | 448 | .292 | 279 | .412 | 285 | .420 | 68.4 | 3.7 | 3.38 | 3.40 |
| Brian Burres* | WAS | mr | 27 | .878 | 87 | .368 | 71 | .530 | 72 | .537 | 23.0 | 7.6 | 6.82 | 7.23 |
| Jared Burton | NYA | mr | 27 | .594 | 107 | .234 | 60 | .364 | 63 | .382 | 12.7 | 2.9 | 2.59 | 2.95 |
| Dave Bush | CIN | sp | 28 | .886 | 561 | .333 | 412 | .544 | 418 | .552 | 132.4 | 7.2 | 6.50 | 6.02 |
| Paul Byrd | NYM | sp | 37 | .798 | 305 | .298 | 184 | .477 | 190 | .492 | 56.2 | 5.7 | 5.13 | 4.77 |
| Tim Byrdak* | PIT | mr | 34 | .679 | 124 | .315 | 81 | .407 | 82 | .412 | 21.5 | 4.3 | 3.87 | 3.76 |
| Daniel Cabrera | WAS | sp | 27 | .794 | 608 | .314 | 446 | .484 | 454 | .492 | 129.6 | 5.8 | 5.23 | 5.43 |
| Matt Cain | LAD | sp | 23 | .706 | 317 | .256 | 220 | .451 | 223 | .457 | 55.7 | 4.4 | 3.94 | 3.66 |
| Matt Cain | CAL | sp | 23 | .843 | 234 | .342 | 174 | .506 | 178 | .517 | 54.9 | 6.7 | 6.04 | 5.91 |
| Matt Cain |   | sp | 23 | .762 | 551 | .292 | 394 | .474 | 401 | .482 | 109.9 | 5.3 | 4.73 | 4.51 |
| Kevin Cameron | CAL | mr | 28 | .731 | 154 | .325 | 107 | .440 | 108 | .444 | 28.2 | 4.8 | 4.39 | 5.09 |
| Matt Capps | CWS | mr | 24 | .488 | 222 | .239 | 82 | .282 | 82 | .282 | 15.8 | 1.8 | 1.66 | 1.51 |
| Chris Capuano* | BAL | sp | 29 | .942 | 402 | .356 | 374 | .585 | 377 | .590 | 118.1 | 7.8 | 7.07 | 7.78 |
| Fausto Carmona | PIT | sp | 24 | .602 | 660 | .264 | 314 | .351 | 329 | .368 | 71.0 | 2.8 | 2.60 | 2.54 |
| Chris Carpenter | MIN | sp | 33 | .895 | 17 | .176 | 12 | .522 | 12 | .522 | 3.9 | 7.4 | 7.21 | 7.33 |
| Santiago Casilla | STL | mr | 27 | .671 | 121 | .190 | 93 | .458 | 95 | .468 | 20.3 | 3.6 | 3.19 | 2.61 |
| Gustavo Chacin* | CHI | sp | 27 | 1.508 | 42 | .452 | 60 | .968 | 60 | .968 | 28.7 | 25.0 | 21.77 | 20.09 |
| Shawn Chacon | NYM | mr | 30 | .888 | 296 | .328 | 224 | .540 | 228 | .549 | 71.4 | 7.1 | 6.52 | 5.84 |
| Matt Chico* | BOS | sp | 25 | .896 | 227 | .313 | 178 | .555 | 180 | .561 | 56.7 | 7.5 | 6.65 | 6.40 |
| Vinnie Chulk | DET | mr | 29 | .704 | 129 | .279 | 78 | .438 | 78 | .438 | 19.6 | 4.1 | 3.78 | 3.57 |
| Roger Clemens | NYA | sp | 45 | .815 | 203 | .335 | 137 | .498 | 138 | .502 | 42.8 | 6.2 | 5.60 | 4.95 |
| Jesus Colome | CLE | mr | 30 | .766 | 205 | .351 | 122 | .439 | 124 | .446 | 38.2 | 5.8 | 5.28 | 5.51 |
| Jose Contreras | MIL | sp | 36 | .751 | 236 | .284 | 138 | .451 | 142 | .464 | 38.3 | 4.7 | 4.42 | 4.13 |
| Jose Contreras | CIN | sp | 36 | .860 | 345 | .307 | 227 | .509 | 236 | .529 | 70.7 | 6.4 | 5.89 | 6.09 |
| Jose Contreras |   | sp | 36 | .816 | 581 | .298 | 365 | .485 | 378 | .503 | 108.8 | 5.7 | 5.25 | 5.24 |
| Aaron Cook | MIN | sp | 29 | .782 | 546 | .322 | 308 | .463 | 312 | .469 | 88.4 | 5.2 | 4.67 | 4.52 |
| Chad Cordero | CLE | cl | 26 | .745 | 121 | .372 | 69 | .418 | 70 | .424 | 20.6 | 5.1 | 4.54 | 5.04 |
| Chad Cordero | DET | cl | 26 | .836 | 82 | .390 | 60 | .492 | 60 | .492 | 17.5 | 5.8 | 5.26 | 5.60 |
| Chad Cordero |   | cl | 26 | .784 | 203 | .379 | 129 | .449 | 130 | .453 | 38.2 | 5.4 | 4.86 | 5.28 |
| Francisco Cordero | NYA | cl | 33 | .702 | 129 | .349 | 95 | .422 | 97 | .431 | 24.5 | 4.2 | 3.77 | 3.91 |
| Manny Corpas | PIT | mr | 25 | .600 | 134 | .254 | 64 | .356 | 66 | .367 | 14.4 | 3.0 | 2.68 | 3.15 |
| Kevin Correia | LAD | mr | 27 | .634 | 301 | .276 | 168 | .386 | 171 | .393 | 39.7 | 3.4 | 3.04 | 2.91 |
| Neal Cotts* | CLE | mr | 28 | .756 | 46 | .304 | 34 | .447 | 37 | .487 | 8.8 | 4.6 | 4.20 | 4.60 |
| Juan Cruz | NYM | mr | 29 | .645 | 127 | .299 | 110 | .420 | 111 | .424 | 25.1 | 3.7 | 3.33 | 2.85 |
| John Danks* | BOS | sp | 23 | .878 | 312 | .301 | 269 | .570 | 270 | .572 | 77.3 | 6.4 | 5.85 | 5.51 |
| Kyle Davies | WAS | sp | 24 | .968 | 405 | .311 | 367 | .606 | 371 | .612 | 123.7 | 8.9 | 7.95 | 7.74 |
| Doug Davis* | MIL | sp | 32 | .873 | 542 | .369 | 403 | .523 | 406 | .527 | 130.0 | 7.3 | 6.49 | 6.73 |
| Jorge De La Rosa* | NYM | sp | 27 | .625 | 27 | .259 | 11 | .355 | 11 | .355 | 2.6 | 2.9 | 2.63 | 2.74 |
| Manny Delcarmen | KCA | mr | 26 | .632 | 104 | .154 | 75 | .426 | 77 | .438 | 16.0 | 3.4 | 3.02 | 3.03 |
| Ryan Dempster | BAL | cl | 31 | .826 | 155 | .297 | 129 | .540 | 129 | .540 | 36.8 | 6.2 | 5.55 | 4.84 |
| Lenny DiNardo* | NYM | sp | 28 | .852 | 421 | .347 | 277 | .504 | 281 | .511 | 81.6 | 6.0 | 5.51 | 6.03 |
| Brendan Donnelly | BOS | mr | 36 | .768 | 53 | .321 | 29 | .382 | 36 | .474 | 10.3 | 5.9 | 5.47 | 4.95 |
| Scott Downs* | NYM | mr | 32 | .803 | 152 | .375 | 109 | .478 | 110 | .482 | 35.1 | 6.6 | 6.06 | 6.06 |
| Brandon Duckworth | CLE | mr | 32 | .456 | 35 | .143 | 15 | .319 | 15 | .319 | 2.1 | 1.6 | 1.44 | 1.88 |
| Zach Duke* | CHI | sp | 25 | 1.173 | 298 | .409 | 273 | .732 | 274 | .735 | 104.9 | 12.7 | 11.38 | 11.29 |
| Chad Durbin | NYM | sp | 30 | .829 | 428 | .290 | 274 | .488 | 290 | .517 | 86.5 | 6.2 | 5.56 | 5.30 |
| J.D. Durbin | WAS | sp | 26 | .698 | 196 | .306 | 115 | .417 | 116 | .420 | 28.6 | 3.9 | 3.56 | 3.98 |
| Alan Embree* | BOS | cl | 38 | .734 | 125 | .328 | 71 | .418 | 74 | .435 | 20.6 | 4.7 | 4.14 | 3.96 |
| Alan Embree* | MIN | cl | 38 | .763 | 85 | .306 | 51 | .477 | 51 | .477 | 13.1 | 4.6 | 3.99 | 3.62 |
| Alan Embree* |   | cl | 38 | .746 | 210 | .319 | 122 | .440 | 125 | .451 | 33.8 | 4.7 | 4.09 | 3.83 |
| Kelvim Escobar | NYA | sp | 32 | .679 | 562 | .286 | 340 | .419 | 344 | .424 | 83.2 | 3.8 | 3.44 | 3.27 |
| Kyle Farnsworth | CLE | mr | 32 | .723 | 157 | .217 | 117 | .476 | 119 | .484 | 29.1 | 4.5 | 4.03 | 3.77 |
| Pedro Feliciano* | STL | mr | 31 | .739 | 153 | .255 | 120 | .472 | 123 | .484 | 30.2 | 4.7 | 4.14 | 4.20 |
| Josh Fogg | SFG | sp | 31 | .995 | 215 | .391 | 168 | .596 | 172 | .610 | 60.8 | 9.3 | 8.54 | 7.67 |
| Jeff Francis* | DET | sp | 27 | .754 | 545 | .317 | 361 | .459 | 366 | .466 | 98.2 | 4.8 | 4.38 | 4.48 |
| Frank Francisco | PHI | mr | 28 | .899 | 133 | .353 | 116 | .555 | 118 | .565 | 35.5 | 7.1 | 6.40 | 5.77 |
| Ryan Franklin | CWS | mr | 35 | .714 | 228 | .272 | 135 | .441 | 136 | .444 | 34.9 | 4.3 | 3.85 | 3.46 |
| Jason Frasor | SFG | mr | 30 | .837 | 132 | .364 | 107 | .517 | 107 | .517 | 33.2 | 6.7 | 5.97 | 5.39 |
| Brian Fuentes* | LAD | cl | 32 | .826 | 44 | .364 | 36 | .507 | 36 | .507 | 11.3 | 7.3 | 6.54 | 7.09 |
| Brian Fuentes* | NYA | cl | 32 | .654 | 90 | .278 | 73 | .415 | 77 | .438 | 16.6 | 3.8 | 3.33 | 3.52 |
| Brian Fuentes* |   | cl | 32 | .704 | 134 | .306 | 109 | .441 | 113 | .457 | 27.5 | 4.6 | 4.10 | 4.38 |
| Aaron Fultz* | CAL | mr | 34 | .770 | 91 | .297 | 71 | .480 | 71 | .480 | 19.1 | 5.3 | 4.95 | 5.21 |
| Kason Gabbard* | CAL | sp | 26 | .714 | 226 | .257 | 149 | .440 | 153 | .451 | 38.3 | 4.3 | 3.94 | 3.83 |
| Eric Gagne | MIL | cl | 32 | .661 | 93 | .280 | 62 | .405 | 65 | .425 | 14.7 | 3.8 | 3.51 | 3.20 |
| Eric Gagne | BOS | cl | 32 | 1.114 | 48 | .396 | 53 | .679 | 54 | .692 | 18.3 | 11.0 | 9.65 | 10.19 |
| Eric Gagne |   | cl | 32 | .811 | 141 | .319 | 115 | .498 | 119 | .515 | 31.7 | 5.7 | 5.20 | 5.10 |
| Yovani Gallardo | MIL | sp | 22 | .864 | 167 | .383 | 124 | .519 | 124 | .519 | 39.4 | 6.9 | 6.18 | 6.07 |
| Yovani Gallardo | PIT | sp | 22 | .832 | 81 | .346 | 60 | .500 | 61 | .508 | 19.7 | 7.2 | 6.48 | 5.98 |
| Yovani Gallardo |   | sp | 22 | .854 | 248 | .371 | 184 | .513 | 185 | .515 | 59.2 | 7.0 | 6.29 | 6.04 |
| Lee Gardner | PIT | mr | 33 | .658 | 231 | .312 | 115 | .373 | 119 | .386 | 30.0 | 3.7 | 3.46 | 3.48 |
| Jon Garland | KCA | sp | 28 | .752 | 596 | .294 | 361 | .466 | 362 | .467 | 93.7 | 4.6 | 4.08 | 3.85 |
| Matt Garza | CAL | sp | 24 | .717 | 215 | .372 | 147 | .425 | 148 | .428 | 39.9 | 4.5 | 4.18 | 4.65 |
| Chad Gaudin | CIN | sp | 25 | .942 | 245 | .343 | 210 | .588 | 211 | .591 | 68.0 | 8.0 | 7.18 | 6.82 |
| Chad Gaudin | STL | sp | 25 | .867 | 247 | .316 | 197 | .543 | 200 | .551 | 59.9 | 6.6 | 5.97 | 5.63 |
| Chad Gaudin |   | sp | 25 | .904 | 492 | .329 | 407 | .565 | 411 | .571 | 127.7 | 7.3 | 6.55 | 6.21 |
| Geoff Geary | BOS | mr | 31 | .898 | 80 | .275 | 61 | .530 | 66 | .574 | 17.6 | 6.0 | 5.36 | 5.84 |
| Justin Germano | CAL | sp | 25 | .863 | 396 | .364 | 281 | .506 | 289 | .521 | 88.8 | 6.6 | 5.93 | 6.24 |
| Tom Glavine* | LAD | sp | 42 | .814 | 685 | .317 | 411 | .483 | 415 | .488 | 119.9 | 5.6 | 5.06 | 5.20 |
| Jimmy Gobble* | PHI | mr | 26 | .830 | 86 | .384 | 59 | .484 | 60 | .492 | 18.2 | 6.4 | 5.83 | 6.25 |
| Edgar Gonzalez | CWS | mr | 25 | 1.059 | 75 | .467 | 64 | .593 | 67 | .620 | 26.0 | 11.3 | 10.01 | 9.42 |
| Tom Gorzelanny* | PIT | sp | 25 | .765 | 468 | .312 | 293 | .448 | 305 | .466 | 86.7 | 5.4 | 4.84 | 4.69 |
| John Grabow* | NYM | mr | 29 | .607 | 40 | .250 | 19 | .345 | 20 | .364 | 5.2 | 3.6 | 3.24 | 2.25 |
| Sean Green | MIL | mr | 29 | .811 | 134 | .388 | 91 | .455 | 96 | .480 | 28.2 | 6.3 | 5.70 | 6.49 |
| Kevin Gregg | CAL | cl | 30 | .754 | 154 | .312 | 126 | .474 | 129 | .485 | 33.0 | 5.1 | 4.59 | 4.93 |
| Zack Greinke | CHI | mr | 24 | .751 | 318 | .299 | 212 | .468 | 214 | .472 | 55.5 | 4.6 | 4.13 | 3.86 |
| Jason Grilli | SFG | mr | 31 | .675 | 144 | .264 | 79 | .395 | 85 | .425 | 20.6 | 3.9 | 3.60 | 3.59 |
| Matt Guerrier | PHI | mr | 29 | .542 | 213 | .225 | 102 | .325 | 108 | .344 | 20.8 | 2.3 | 2.08 | 1.77 |
| Jeremy Guthrie | CHI | sp | 29 | .656 | 512 | .252 | 292 | .407 | 299 | .417 | 69.1 | 3.5 | 3.14 | 2.79 |
| Roy Halladay | NYA | sp | 31 | .630 | 699 | .290 | 337 | .366 | 343 | .373 | 78.3 | 3.1 | 2.75 | 2.84 |
| Cole Hamels* | MIN | sp | 24 | .680 | 476 | .311 | 312 | .420 | 316 | .426 | 77.8 | 3.9 | 3.50 | 3.18 |
| Jason Hammel | NYM | sp | 25 | .878 | 21 | .333 | 13 | .500 | 14 | .538 | 3.8 | 6.1 | 5.80 | 6.62 |
| Justin Hampson* | CWS | mr | 28 | .771 | 135 | .356 | 89 | .454 | 91 | .464 | 25.1 | 5.1 | 4.67 | 4.85 |
| Joel Hanrahan | PHI | sp | 26 | .950 | 124 | .282 | 122 | .607 | 122 | .607 | 36.5 | 7.7 | 7.21 | 8.15 |
| Aaron Harang | STL | sp | 30 | .691 | 629 | .289 | 409 | .433 | 414 | .439 | 99.2 | 3.8 | 3.48 | 3.08 |
| Rich Harden | WAS | sp | 26 | .890 | 46 | .348 | 42 | .560 | 42 | .560 | 11.9 | 6.7 | 6.04 | 7.64 |
| Dan Haren | LAD | sp | 27 | .659 | 368 | .291 | 201 | .398 | 203 | .402 | 51.2 | 3.7 | 3.37 | 2.85 |
| Dan Haren | CAL | sp | 27 | .762 | 280 | .350 | 200 | .465 | 201 | .467 | 58.1 | 5.4 | 4.82 | 4.54 |
| Dan Haren |   | sp | 27 | .706 | 648 | .316 | 401 | .429 | 404 | .432 | 108.9 | 4.4 | 4.00 | 3.57 |
| LaTroy Hawkins | SFG | mr | 35 | .646 | 152 | .263 | 74 | .381 | 75 | .387 | 16.9 | 3.2 | 2.96 | 3.35 |
| Aaron Heilman | LAD | mr | 29 | .736 | 245 | .265 | 148 | .453 | 151 | .462 | 40.5 | 4.8 | 4.40 | 4.02 |
| Mark Hendrickson* | WAS | mr | 34 | .764 | 379 | .319 | 231 | .456 | 231 | .456 | 66.4 | 5.2 | 4.82 | 4.87 |
| Brad Hennessey | PHI | cl | 28 | .736 | 218 | .271 | 136 | .456 | 138 | .463 | 34.0 | 4.3 | 3.95 | 3.50 |
| Matt Herges | NYA | mr | 38 | .478 | 144 | .160 | 57 | .313 | 58 | .319 | 7.3 | 1.3 | 1.19 | 1.16 |
| Felix Hernandez | DET | sp | 22 | .868 | 456 | .373 | 370 | .529 | 377 | .539 | 111.2 | 6.4 | 5.86 | 6.03 |
| Livan Hernandez | BOS | sp | 33 | .893 | 302 | .298 | 235 | .560 | 240 | .571 | 71.7 | 7.1 | 6.38 | 6.12 |
| Orlando Hernandez | NYM | sp | 38 | .785 | 387 | .245 | 309 | .511 | 314 | .519 | 83.0 | 5.3 | 4.80 | 4.60 |
| Rich Hill* | BAL | sp | 28 | .740 | 486 | .284 | 367 | .466 | 377 | .478 | 95.3 | 4.6 | 4.18 | 4.10 |
| Shawn Hill | LAD | sp | 27 | .741 | 289 | .298 | 175 | .445 | 180 | .458 | 47.5 | 4.7 | 4.23 | 4.20 |
| Jason Hirsh | CHI | sp | 26 | .882 | 287 | .268 | 244 | .557 | 253 | .578 | 71.1 | 6.5 | 5.76 | 5.11 |
| Trevor Hoffman | BAL | cl | 40 | .694 | 121 | .289 | 79 | .441 | 79 | .441 | 18.9 | 3.9 | 3.53 | 3.04 |
| J.P. Howell* | CIN | sp | 25 | 1.036 | 166 | .404 | 154 | .647 | 155 | .651 | 53.0 | 9.5 | 8.64 | 8.52 |
| Bob Howry | CIN | mr | 34 | .687 | 246 | .280 | 134 | .405 | 139 | .420 | 34.8 | 3.9 | 3.55 | 3.41 |
| Tim Hudson | PHI | sp | 32 | .623 | 297 | .290 | 138 | .359 | 140 | .365 | 32.6 | 3.1 | 2.79 | 2.73 |
| Tim Hudson | KCA | sp | 32 | .656 | 370 | .268 | 193 | .402 | 195 | .406 | 43.5 | 3.2 | 2.98 | 2.95 |
| Tim Hudson |   | sp | 32 | .641 | 667 | .277 | 331 | .383 | 335 | .388 | 76.2 | 3.2 | 2.90 | 2.86 |
| Phil Hughes | CIN | sp | 22 | .783 | 63 | .317 | 44 | .463 | 46 | .484 | 13.2 | 5.6 | 5.17 | 4.83 |
| Phil Hughes | CLE | sp | 22 | .446 | 136 | .140 | 61 | .290 | 65 | .310 | 10.0 | 1.6 | 1.50 | 1.30 |
| Phil Hughes |   | sp | 22 | .551 | 199 | .196 | 105 | .344 | 111 | .364 | 21.7 | 2.5 | 2.36 | 2.03 |
| Jason Isringhausen | STL | cl | 35 | .551 | 171 | .193 | 88 | .349 | 91 | .361 | 16.3 | 2.2 | 2.02 | 1.86 |
| Edwin Jackson | MIL | sp | 24 | .912 | 421 | .361 | 354 | .563 | 355 | .564 | 115.7 | 7.9 | 7.19 | 6.98 |
| Chuck James* | KCA | sp | 26 | .674 | 283 | .226 | 178 | .432 | 179 | .434 | 43.3 | 4.0 | 3.63 | 3.39 |
| Casey Janssen | HOU | mr | 26 | .768 | 138 | .341 | 80 | .447 | 82 | .458 | 23.4 | 5.1 | 4.83 | 4.76 |
| Casey Janssen | STL | mr | 26 | .711 | 92 | .315 | 48 | .410 | 49 | .419 | 11.7 | 3.7 | 3.34 | 3.61 |
| Casey Janssen |   | mr | 26 | .746 | 230 | .330 | 128 | .432 | 131 | .443 | 35.0 | 4.5 | 4.19 | 4.27 |
| Bobby Jenks | DET | cl | 27 | .585 | 174 | .305 | 80 | .332 | 81 | .336 | 19.2 | 2.9 | 2.73 | 2.78 |
| Jason Jennings | PIT | sp | 29 | 1.617 | 12 | .500 | 14 | .933 | 14 | .933 | 7.6 | 29.4 | 30.89 | 25.41 |
| Ubaldo Jimenez | LAD | sp | 24 | .725 | 54 | .333 | 37 | .451 | 37 | .451 | 9.3 | 4.4 | 3.91 | 3.91 |
| Ubaldo Jimenez | CAL | sp | 24 | .617 | 190 | .226 | 107 | .395 | 109 | .402 | 23.7 | 3.2 | 3.03 | 2.65 |
| Ubaldo Jimenez |   | sp | 24 | .642 | 244 | .250 | 144 | .408 | 146 | .414 | 32.9 | 3.5 | 3.23 | 2.93 |
| Josh Johnson | MIL | sp | 24 | .929 | 71 | .408 | 47 | .516 | 47 | .516 | 16.0 | 7.7 | 6.72 | 7.94 |
| Randy Johnson* | KCA | sp | 44 | .700 | 99 | .374 | 79 | .403 | 86 | .439 | 21.4 | 4.3 | 3.83 | 4.18 |
| Tyler Johnson* | STL | mr | 27 | .580 | 106 | .236 | 55 | .364 | 55 | .364 | 12.4 | 3.0 | 2.75 | 2.50 |
| Todd Jones | CIN | cl | 40 | .705 | 151 | .265 | 82 | .427 | 82 | .427 | 18.9 | 3.6 | 3.24 | 3.41 |
| Jorge Julio | BAL | mr | 29 | .921 | 129 | .364 | 120 | .569 | 121 | .573 | 40.0 | 8.2 | 7.20 | 7.15 |
| Scott Kazmir* | CIN | sp | 24 | .797 | 214 | .364 | 195 | .494 | 200 | .506 | 56.2 | 5.8 | 5.30 | 5.15 |
| Scott Kazmir* | CLE | sp | 24 | .708 | 245 | .302 | 197 | .453 | 199 | .457 | 48.3 | 4.2 | 3.77 | 3.46 |
| Scott Kazmir* |   | sp | 24 | .750 | 459 | .331 | 392 | .472 | 399 | .481 | 104.3 | 4.9 | 4.45 | 4.21 |
| Kyle Kendrick | MIL | sp | 23 | .781 | 359 | .262 | 206 | .482 | 211 | .494 | 53.4 | 4.6 | 4.21 | 4.12 |
| Joe Kennedy* | LAD | mr | 29 | .733 | 52 | .231 | 27 | .443 | 28 | .459 | 7.0 | 4.3 | 4.04 | 4.71 |
| Logan Kensing | PIT | mr | 25 | 1.027 | 35 | .429 | 30 | .588 | 32 | .627 | 12.2 | 11.0 | 9.54 | 10.59 |
| Ray King* | NYM | mr | 34 | 1.027 | 120 | .383 | 100 | .617 | 103 | .636 | 34.7 | 9.5 | 8.43 | 8.82 |
| John Lackey | KCA | sp | 29 | .613 | 598 | .281 | 306 | .355 | 320 | .371 | 73.9 | 3.1 | 2.87 | 2.84 |
| Aaron Laffey* | HOU | sp | 23 | .705 | 103 | .320 | 49 | .405 | 49 | .405 | 11.9 | 3.6 | 3.33 | 3.60 |
| Aaron Laffey* | STL | sp | 23 | .689 | 63 | .333 | 31 | .383 | 32 | .395 | 9.2 | 4.5 | 3.98 | 3.75 |
| Aaron Laffey* |   | sp | 23 | .699 | 166 | .325 | 80 | .396 | 81 | .401 | 21.2 | 3.9 | 3.60 | 3.66 |
| John Lannan* | SFG | sp | 23 | 1.200 | 15 | .267 | 18 | .783 | 18 | .783 | 6.8 | 15.4 | 13.85 | 14.92 |
| John Lannan* | WAS | sp | 23 | .867 | 82 | .293 | 59 | .532 | 61 | .550 | 18.6 | 7.4 | 6.64 | 6.61 |
| John Lannan* |   | sp | 23 | .922 | 97 | .289 | 77 | .575 | 79 | .590 | 25.1 | 8.5 | 7.62 | 7.76 |
| Brandon League | WAS | mr | 25 | .629 | 37 | .270 | 16 | .364 | 16 | .364 | 4.0 | 3.3 | 3.01 | 3.39 |
| Cliff Lee* | PHI | sp | 29 | .855 | 300 | .263 | 234 | .543 | 240 | .557 | 63.5 | 5.7 | 5.13 | 5.07 |
| Jon Lester* | HOU | sp | 24 | .804 | 184 | .304 | 125 | .483 | 128 | .494 | 38.0 | 5.9 | 5.33 | 5.20 |
| Brad Lidge | PHI | cl | 31 | .606 | 144 | .257 | 94 | .388 | 96 | .397 | 20.8 | 3.1 | 2.86 | 2.18 |
| Jon Lieber | PHI | sp | 38 | .772 | 295 | .315 | 175 | .464 | 177 | .469 | 51.0 | 5.3 | 4.76 | 4.18 |
| Ted Lilly* | SFG | sp | 32 | .798 | 561 | .291 | 402 | .500 | 408 | .507 | 114.1 | 5.5 | 5.04 | 4.63 |
| Tim Lincecum | WAS | sp | 24 | .727 | 390 | .269 | 288 | .469 | 289 | .471 | 68.3 | 4.1 | 3.75 | 3.64 |
| Matt Lindstrom | CAL | mr | 28 | .615 | 173 | .301 | 88 | .345 | 93 | .365 | 22.5 | 3.3 | 2.95 | 3.03 |
| Scott Linebrink | CLE | mr | 31 | .875 | 189 | .270 | 158 | .560 | 160 | .567 | 46.9 | 6.7 | 6.03 | 6.02 |
| Jesse Litsch | LAD | sp | 23 | .864 | 88 | .341 | 52 | .500 | 53 | .510 | 16.4 | 6.3 | 5.69 | 5.64 |
| Jesse Litsch | CAL | sp | 23 | .739 | 285 | .291 | 161 | .438 | 165 | .448 | 40.1 | 4.0 | 3.61 | 4.04 |
| Jesse Litsch |   | sp | 23 | .767 | 373 | .303 | 213 | .451 | 218 | .462 | 56.1 | 4.5 | 4.01 | 4.36 |
| Wes Littleton | LAD | mr | 25 | .819 | 144 | .271 | 104 | .505 | 107 | .519 | 29.2 | 5.8 | 5.14 | 5.56 |
| Kameron Loe | NYM | sp | 26 | .561 | 33 | .273 | 18 | .353 | 18 | .353 | 3.7 | 2.7 | 2.44 | 2.32 |
| Adam Loewen* | NYM | sp | 24 | .746 | 108 | .296 | 78 | .462 | 81 | .479 | 19.8 | 4.9 | 4.50 | 5.36 |
| Boone Logan* | NYM | mr | 23 | .977 | 154 | .396 | 121 | .579 | 121 | .579 | 43.6 | 9.5 | 8.48 | 9.14 |
| Kyle Lohse | MIN | sp | 29 | .761 | 563 | .295 | 359 | .467 | 366 | .476 | 99.8 | 5.0 | 4.52 | 3.95 |
| Braden Looper | CAL | sp | 33 | .814 | 543 | .315 | 369 | .495 | 374 | .501 | 107.8 | 5.8 | 5.22 | 5.18 |
| Javier Lopez* | LAD | mr | 30 | .564 | 131 | .168 | 60 | .349 | 64 | .372 | 12.5 | 2.6 | 2.40 | 2.57 |
| Rodrigo Lopez | STL | sp | 32 | .851 | 268 | .295 | 184 | .538 | 185 | .541 | 53.4 | 6.1 | 5.45 | 4.86 |
| Derek Lowe | CWS | sp | 35 | .719 | 556 | .300 | 354 | .438 | 360 | .446 | 91.2 | 4.3 | 3.93 | 3.93 |
| Noah Lowry* | CAL | sp | 27 | .929 | 248 | .355 | 209 | .563 | 213 | .574 | 66.3 | 7.8 | 7.10 | 8.32 |
| Brandon Lyon | MIN | mr | 28 | .657 | 234 | .295 | 117 | .389 | 117 | .389 | 29.8 | 3.7 | 3.40 | 3.22 |
| Greg Maddux | BAL | sp | 42 | .754 | 667 | .313 | 371 | .448 | 375 | .453 | 107.9 | 5.0 | 4.54 | 4.07 |
| Ryan Madson | CAL | mr | 27 | .840 | 166 | .313 | 117 | .506 | 118 | .511 | 35.2 | 6.2 | 5.70 | 5.72 |
| Ron Mahay* | CAL | mr | 37 | .872 | 135 | .385 | 125 | .543 | 125 | .543 | 39.7 | 7.5 | 6.69 | 6.54 |
| Paul Maholm* | PHI | sp | 26 | .872 | 528 | .318 | 379 | .528 | 387 | .539 | 110.6 | 6.1 | 5.60 | 6.31 |
| John Maine | PHI | sp | 27 | .822 | 521 | .307 | 410 | .515 | 416 | .523 | 115.3 | 5.6 | 5.14 | 4.93 |
| Shaun Marcum | CHI | sp | 26 | .807 | 455 | .303 | 324 | .495 | 333 | .508 | 91.3 | 5.4 | 4.84 | 5.00 |
| Carlos Marmol | CHI | mr | 25 | .620 | 145 | .241 | 114 | .400 | 116 | .407 | 25.0 | 3.3 | 2.96 | 3.11 |
| Jason Marquis | HOU | sp | 29 | .671 | 597 | .263 | 315 | .397 | 329 | .415 | 76.9 | 3.6 | 3.28 | 3.27 |
| Sean Marshall* | NYM | sp | 25 | .845 | 331 | .320 | 232 | .520 | 233 | .522 | 70.3 | 6.4 | 5.75 | 5.72 |
| Damaso Marte* | MIL | mr | 33 | .784 | 112 | .330 | 90 | .497 | 91 | .503 | 24.0 | 5.1 | 4.45 | 3.90 |
| Pedro Martinez | NYA | sp | 36 | .950 | 69 | .493 | 54 | .557 | 55 | .567 | 19.9 | 8.8 | 7.55 | 6.09 |
| Daisuke Matsuzaka | DET | sp | 27 | .794 | 452 | .301 | 379 | .499 | 388 | .511 | 103.2 | 5.2 | 4.74 | 4.74 |
| Brandon McCarthy | DET | sp | 24 | .952 | 271 | .306 | 234 | .597 | 238 | .607 | 75.0 | 8.2 | 7.54 | 7.48 |
| Dustin McGowan | NYA | sp | 26 | .638 | 465 | .275 | 274 | .400 | 275 | .401 | 66.6 | 3.6 | 3.36 | 2.87 |
| Gil Meche | CHI | sp | 29 | .684 | 628 | .263 | 364 | .424 | 367 | .428 | 87.4 | 3.7 | 3.37 | 3.27 |
| Cla Meredith | DET | mr | 25 | .732 | 204 | .304 | 121 | .438 | 122 | .442 | 29.6 | 4.0 | 3.56 | 4.16 |
| Andrew Miller* | HOU | sp | 23 | .797 | 184 | .332 | 142 | .485 | 145 | .495 | 42.1 | 6.0 | 5.41 | 5.31 |
| Justin Miller | HOU | mr | 30 | .694 | 179 | .285 | 111 | .430 | 112 | .434 | 27.3 | 3.9 | 3.54 | 3.09 |
| Trever Miller* | BOS | mr | 35 | .956 | 48 | .479 | 46 | .561 | 47 | .573 | 16.4 | 9.0 | 7.96 | 7.47 |
| Kevin Millwood | BAL | sp | 33 | .689 | 565 | .276 | 328 | .423 | 329 | .425 | 79.6 | 3.8 | 3.50 | 3.58 |
| Zach Miner | KCA | mr | 26 | .477 | 170 | .200 | 69 | .297 | 70 | .302 | 11.4 | 1.7 | 1.58 | 1.57 |
| Sergio Mitre | PHI | sp | 27 | .831 | 444 | .324 | 275 | .476 | 288 | .498 | 86.8 | 6.1 | 5.48 | 5.46 |
| Brian Moehler | NYM | mr | 36 | .824 | 68 | .353 | 44 | .478 | 45 | .489 | 12.4 | 5.3 | 4.71 | 4.61 |
| Franklin Morales* | BOS | sp | 22 | .730 | 83 | .301 | 56 | .459 | 56 | .459 | 12.3 | 3.7 | 3.36 | 4.09 |
| Matt Morris | NYM | sp | 33 | .858 | 699 | .320 | 454 | .516 | 463 | .526 | 142.5 | 6.7 | 6.08 | 5.78 |
| Brandon Morrow | NYM | mr | 23 | .912 | 162 | .383 | 153 | .565 | 154 | .568 | 48.9 | 8.2 | 7.47 | 7.65 |
| Dustin Moseley | NYA | mr | 26 | .576 | 206 | .262 | 96 | .337 | 99 | .347 | 21.1 | 2.7 | 2.43 | 2.34 |
| Guillermo Mota | CLE | mr | 34 | .837 | 117 | .342 | 92 | .523 | 92 | .523 | 27.7 | 6.3 | 5.75 | 5.49 |
| Jamie Moyer* | BOS | sp | 45 | .884 | 537 | .341 | 411 | .544 | 415 | .549 | 129.6 | 7.1 | 6.32 | 6.07 |
| Peter Moylan | PIT | mr | 29 | .733 | 270 | .300 | 156 | .436 | 162 | .453 | 38.8 | 4.0 | 3.62 | 3.92 |
| Mike Mussina | CLE | sp | 39 | .790 | 499 | .343 | 304 | .468 | 309 | .475 | 92.0 | 5.5 | 5.05 | 4.65 |
| Brett Myers | LAD | cl | 27 | .614 | 170 | .276 | 106 | .369 | 112 | .390 | 26.0 | 3.5 | 3.15 | 2.98 |
| Joe Nathan | MIL | cl | 33 | .676 | 105 | .305 | 68 | .415 | 68 | .415 | 15.8 | 3.5 | 3.28 | 3.18 |
| Joe Nathan | MIN | cl | 33 | .598 | 72 | .333 | 38 | .339 | 39 | .348 | 9.9 | 3.4 | 2.98 | 2.70 |
| Joe Nathan |   | cl | 33 | .644 | 177 | .316 | 106 | .384 | 107 | .388 | 25.8 | 3.5 | 3.17 | 2.99 |
| Pat Neshek | CIN | mr | 27 | .783 | 99 | .333 | 85 | .491 | 87 | .503 | 25.0 | 5.7 | 5.14 | 4.37 |
| Pat Neshek | STL | mr | 27 | .601 | 56 | .196 | 44 | .415 | 44 | .415 | 7.9 | 2.5 | 2.25 | 1.93 |
| Pat Neshek |   | mr | 27 | .714 | 155 | .284 | 129 | .462 | 131 | .470 | 32.2 | 4.3 | 3.85 | 3.29 |
| Dustin Nippert | CWS | mr | 27 | 1.139 | 12 | .500 | 11 | .611 | 11 | .611 | 5.0 | 17.0 | 15.32 | 16.21 |
| Leo Nunez | CWS | mr | 24 | .766 | 77 | .325 | 56 | .471 | 56 | .471 | 16.1 | 5.4 | 4.89 | 4.39 |
| Eric O'Flaherty* | PHI | mr | 23 | .691 | 145 | .255 | 76 | .413 | 79 | .429 | 18.6 | 3.7 | 3.37 | 3.19 |
| Hideki Okajima* | CHI | mr | 32 | .709 | 145 | .297 | 100 | .450 | 100 | .450 | 24.7 | 4.1 | 3.62 | 3.44 |
| Darren Oliver* | BAL | mr | 37 | .655 | 155 | .252 | 92 | .411 | 93 | .415 | 21.8 | 3.7 | 3.29 | 3.33 |
| Scott Olsen* | MIL | sp | 24 | .970 | 191 | .366 | 153 | .595 | 153 | .595 | 53.2 | 9.0 | 8.29 | 8.23 |
| Scott Olsen* | WAS | sp | 24 | .842 | 300 | .323 | 231 | .524 | 231 | .524 | 68.3 | 6.5 | 5.78 | 5.80 |
| Scott Olsen* |   | sp | 24 | .891 | 491 | .340 | 384 | .550 | 384 | .550 | 121.1 | 7.4 | 6.64 | 6.64 |
| Garrett Olson* | WAS | sp | 24 | 1.098 | 104 | .394 | 108 | .667 | 111 | .685 | 41.6 | 12.8 | 11.62 | 12.97 |
| Ramon Ortiz | LAD | mr | 35 | .701 | 46 | .283 | 20 | .385 | 21 | .404 | 5.5 | 3.9 | 3.54 | 3.64 |
| Roy Oswalt | CWS | sp | 30 | .712 | 569 | .308 | 341 | .429 | 344 | .433 | 90.2 | 4.4 | 3.92 | 3.90 |
| Akinori Otsuka | NYA | mr | 36 | .626 | 60 | .300 | 37 | .374 | 39 | .394 | 9.1 | 3.4 | 3.03 | 2.55 |
| Micah Owings | MIN | sp | 25 | .789 | 418 | .299 | 306 | .476 | 321 | .499 | 88.2 | 5.4 | 4.90 | 5.03 |
| Vicente Padilla | BOS | sp | 30 | .945 | 197 | .345 | 165 | .563 | 171 | .584 | 54.8 | 8.1 | 7.36 | 8.32 |
| Vicente Padilla | MIN | sp | 30 | .835 | 147 | .401 | 87 | .468 | 89 | .478 | 31.4 | 7.3 | 6.47 | 6.45 |
| Vicente Padilla |   | sp | 30 | .901 | 344 | .369 | 252 | .526 | 260 | .543 | 86.2 | 7.8 | 7.01 | 7.56 |
| Jonathan Papelbon | NYA | cl | 27 | .648 | 114 | .246 | 92 | .411 | 97 | .433 | 21.3 | 3.4 | 3.12 | 2.78 |
| Chad Paronto | MIL | mr | 32 | .887 | 47 | .362 | 26 | .433 | 29 | .483 | 10.1 | 7.8 | 7.00 | 7.98 |
| John Patterson | CWS | sp | 30 | .725 | 83 | .289 | 47 | .431 | 47 | .431 | 12.2 | 4.3 | 3.80 | 3.92 |
| Jake Peavy | CHI | sp | 27 | .652 | 599 | .284 | 354 | .399 | 360 | .406 | 83.8 | 3.4 | 3.08 | 2.77 |
| Mike Pelfrey | MIL | sp | 24 | .822 | 176 | .341 | 128 | .490 | 131 | .502 | 35.8 | 5.6 | 5.20 | 6.17 |
| Tony Pena | STL | mr | 26 | .708 | 233 | .227 | 144 | .434 | 151 | .455 | 37.1 | 4.2 | 3.82 | 3.61 |
| Brad Penny | SFG | sp | 30 | .845 | 334 | .335 | 237 | .510 | 240 | .516 | 73.4 | 6.5 | 5.81 | 5.69 |
| Brad Penny | DET | sp | 30 | .760 | 225 | .271 | 142 | .470 | 143 | .474 | 38.1 | 4.9 | 4.45 | 4.54 |
| Brad Penny |   | sp | 30 | .812 | 559 | .309 | 379 | .494 | 383 | .499 | 111.2 | 5.8 | 5.25 | 5.22 |
| Joel Peralta | BAL | mr | 32 | .720 | 222 | .293 | 135 | .437 | 137 | .443 | 34.6 | 4.1 | 3.66 | 3.45 |
| Troy Percival | CHI | mr | 38 | .723 | 91 | .297 | 70 | .467 | 70 | .467 | 17.5 | 4.3 | 3.95 | 3.53 |
| Odalis Perez* | LAD | sp | 31 | .784 | 60 | .233 | 37 | .463 | 40 | .500 | 11.1 | 6.0 | 5.63 | 6.11 |
| Oliver Perez* | MIL | sp | 26 | .954 | 300 | .340 | 280 | .588 | 285 | .599 | 91.4 | 8.2 | 7.45 | 7.54 |
| Oliver Perez* | CLE | sp | 26 | .651 | 157 | .236 | 106 | .414 | 109 | .426 | 25.0 | 3.6 | 3.27 | 2.98 |
| Oliver Perez* |   | sp | 26 | .846 | 457 | .304 | 386 | .527 | 394 | .538 | 113.8 | 6.3 | 5.71 | 5.65 |
| Rafael Perez* | KCA | mr | 26 | .583 | 140 | .229 | 83 | .379 | 84 | .384 | 16.2 | 2.6 | 2.37 | 2.07 |
| Yusmeiro Petit | WAS | sp | 23 | .792 | 151 | .238 | 114 | .525 | 114 | .525 | 27.8 | 4.7 | 4.30 | 4.15 |
| Andy Pettitte* | PIT | sp | 36 | .684 | 630 | .286 | 350 | .413 | 354 | .417 | 85.2 | 3.7 | 3.40 | 3.21 |
| Joel Pineiro | MIN | mr | 29 | .936 | 256 | .293 | 204 | .596 | 204 | .596 | 60.9 | 7.2 | 6.70 | 6.96 |
| Renyel Pinto* | DET | mr | 25 | .704 | 115 | .348 | 83 | .417 | 86 | .432 | 21.7 | 4.4 | 3.93 | 4.51 |
| Scott Proctor | LAD | mr | 31 | .788 | 250 | .268 | 183 | .491 | 188 | .504 | 50.8 | 5.4 | 4.88 | 4.82 |
| J.J. Putz | CHI | cl | 31 | .453 | 168 | .173 | 78 | .299 | 78 | .299 | 11.7 | 1.5 | 1.33 | 1.23 |
| Chad Qualls | MIN | mr | 29 | .778 | 192 | .385 | 135 | .456 | 138 | .466 | 41.9 | 5.8 | 5.22 | 5.38 |
| Jon Rauch | LAD | mr | 29 | .646 | 223 | .274 | 123 | .393 | 123 | .393 | 29.6 | 3.6 | 3.21 | 3.26 |
| Jon Rauch | NYA | mr | 29 | .869 | 43 | .419 | 32 | .525 | 32 | .525 | 10.2 | 6.7 | 6.03 | 6.17 |
| Jon Rauch |   | mr | 29 | .685 | 266 | .297 | 155 | .414 | 155 | .414 | 39.4 | 4.0 | 3.61 | 3.67 |
| Chris Ray | DET | cl | 26 | .838 | 99 | .323 | 80 | .516 | 81 | .523 | 24.8 | 6.8 | 6.04 | 6.04 |
| Tim Redding | STL | sp | 30 | .922 | 241 | .369 | 186 | .534 | 193 | .555 | 64.5 | 8.3 | 7.43 | 8.03 |
| Al Reyes | CIN | cl | 38 | .745 | 153 | .268 | 118 | .474 | 122 | .490 | 30.6 | 4.8 | 4.29 | 4.27 |
| Anthony Reyes | MIN | sp | 26 | .978 | 101 | .317 | 102 | .626 | 105 | .644 | 33.9 | 9.1 | 7.99 | 7.74 |
| Jo-Jo Reyes* | WAS | sp | 23 | 1.034 | 160 | .325 | 150 | .655 | 150 | .655 | 49.4 | 9.5 | 8.58 | 9.18 |
| John Rheinecker* | NYM | mr | 29 | .920 | 163 | .325 | 135 | .574 | 136 | .579 | 39.9 | 7.0 | 6.34 | 6.84 |
| Juan Rincon | STL | mr | 29 | .679 | 127 | .236 | 76 | .427 | 78 | .438 | 19.0 | 4.0 | 3.69 | 3.47 |
| David Riske | CAL | mr | 31 | .665 | 193 | .295 | 101 | .391 | 102 | .395 | 25.9 | 3.8 | 3.40 | 3.40 |
| Mariano Rivera | NYA | cl | 38 | .646 | 163 | .307 | 91 | .374 | 96 | .395 | 22.1 | 3.3 | 3.01 | 2.77 |
| Saul Rivera | CWS | mr | 30 | .682 | 85 | .329 | 49 | .402 | 50 | .410 | 12.5 | 4.0 | 3.61 | 3.93 |
| Nate Robertson* | HOU | sp | 30 | .837 | 594 | .360 | 382 | .489 | 384 | .492 | 120.9 | 6.4 | 5.81 | 5.72 |
| Fernando Rodney | CHI | mr | 31 | .748 | 112 | .259 | 88 | .484 | 91 | .500 | 21.7 | 4.4 | 4.06 | 3.70 |
| Francisco Rodriguez | SFG | cl | 26 | .685 | 149 | .309 | 112 | .426 | 112 | .426 | 28.8 | 4.1 | 3.80 | 3.42 |
| Wandy Rodriguez* | LAD | sp | 29 | .722 | 552 | .297 | 339 | .434 | 350 | .448 | 91.3 | 4.4 | 4.05 | 3.68 |
| Kenny Rogers* | CHI | sp | 43 | .754 | 173 | .277 | 108 | .474 | 109 | .478 | 28.2 | 4.7 | 4.25 | 3.76 |
| J.C. Romero* | CLE | mr | 32 | .733 | 142 | .268 | 108 | .476 | 108 | .476 | 26.6 | 4.6 | 4.22 | 4.15 |
| Ryan Rowland-Smith* | WAS | mr | 25 | .804 | 94 | .319 | 76 | .497 | 78 | .510 | 20.8 | 5.5 | 4.97 | 4.86 |
| C.C. Sabathia* | NYA | sp | 27 | .754 | 684 | .341 | 439 | .454 | 444 | .459 | 119.2 | 4.6 | 4.15 | 3.91 |
| Takashi Saito | SFG | cl | 38 | .615 | 115 | .226 | 80 | .396 | 82 | .406 | 16.0 | 2.7 | 2.51 | 2.39 |
| Juan Salas | NYM | mr | 29 | .771 | 73 | .219 | 53 | .482 | 57 | .518 | 14.9 | 5.2 | 4.66 | 4.26 |
| Chris Sampson | BOS | sp | 30 | .871 | 302 | .288 | 216 | .535 | 221 | .547 | 65.2 | 6.6 | 5.94 | 5.96 |
| Anibal Sanchez | CAL | sp | 24 | .950 | 89 | .382 | 64 | .561 | 65 | .570 | 23.0 | 9.1 | 8.22 | 7.77 |
| Jonathan Sanchez* | HOU | mr | 25 | .990 | 147 | .483 | 137 | .588 | 137 | .588 | 49.9 | 10.0 | 9.04 | 9.55 |
| Ervin Santana | HOU | sp | 25 | .905 | 452 | .336 | 368 | .562 | 375 | .573 | 117.1 | 7.4 | 6.66 | 6.16 |
| Johan Santana* | KCA | sp | 29 | .657 | 519 | .247 | 368 | .432 | 370 | .435 | 80.4 | 3.4 | 3.03 | 2.69 |
| Joe Saunders* | PHI | sp | 27 | .828 | 335 | .355 | 209 | .478 | 213 | .487 | 63.4 | 5.8 | 5.37 | 5.71 |
| Curt Schilling | BAL | sp | 41 | .824 | 466 | .337 | 311 | .497 | 317 | .506 | 93.9 | 5.9 | 5.28 | 4.97 |
| Scott Schoeneweis* | BOS | mr | 34 | .499 | 16 | .250 | 7 | .304 | 7 | .304 | 1.1 | 1.7 | 1.54 | 1.48 |
| Chris Schroder | CLE | mr | 29 | .900 | 125 | .440 | 100 | .521 | 101 | .526 | 35.1 | 8.2 | 7.47 | 7.85 |
| Rudy Seanez | BOS | mr | 39 | .796 | 141 | .298 | 119 | .500 | 122 | .513 | 33.5 | 5.7 | 5.15 | 5.29 |
| Bobby Seay* | DET | mr | 30 | .698 | 119 | .336 | 76 | .411 | 79 | .427 | 19.7 | 4.1 | 3.66 | 3.40 |
| Ben Sheets | KCA | sp | 29 | .661 | 368 | .299 | 213 | .399 | 216 | .404 | 54.4 | 3.8 | 3.43 | 3.13 |
| George Sherrill* | CHI | mr | 31 | .753 | 105 | .324 | 79 | .465 | 80 | .471 | 21.1 | 4.9 | 4.42 | 4.40 |
| James Shields | CWS | sp | 26 | .696 | 532 | .314 | 355 | .430 | 361 | .438 | 91.4 | 4.1 | 3.73 | 3.26 |
| Scot Shields | PHI | mr | 32 | .609 | 201 | .239 | 112 | .366 | 118 | .386 | 25.3 | 3.0 | 2.72 | 2.79 |
| Brian Shouse* | DET | mr | 39 | .730 | 115 | .348 | 62 | .395 | 67 | .427 | 18.7 | 4.8 | 4.28 | 4.59 |
| Carlos Silva | BOS | sp | 29 | .882 | 372 | .344 | 256 | .529 | 261 | .539 | 83.2 | 7.2 | 6.54 | 6.31 |
| Carlos Silva | MIN | sp | 29 | .725 | 275 | .291 | 145 | .435 | 146 | .438 | 38.6 | 4.3 | 3.88 | 3.75 |
| Carlos Silva |   | sp | 29 | .817 | 647 | .321 | 401 | .491 | 407 | .498 | 120.8 | 5.9 | 5.33 | 5.15 |
| Doug Slaten* | NYM | mr | 28 | 1.072 | 72 | .361 | 68 | .680 | 68 | .680 | 24.4 | 11.4 | 10.05 | 10.22 |
| Kevin Slowey | BOS | sp | 24 | .864 | 201 | .254 | 171 | .578 | 172 | .581 | 47.4 | 6.2 | 5.70 | 4.98 |
| Joe Smith | CIN | mr | 24 | .800 | 123 | .398 | 86 | .437 | 92 | .467 | 27.8 | 5.9 | 5.23 | 5.94 |
| John Smoltz | STL | sp | 41 | .720 | 537 | .324 | 379 | .444 | 383 | .449 | 100.8 | 4.5 | 4.05 | 3.82 |
| Ian Snell | MIL | sp | 26 | .766 | 266 | .323 | 169 | .458 | 171 | .463 | 48.4 | 5.1 | 4.62 | 4.37 |
| Ian Snell | HOU | sp | 26 | .788 | 317 | .322 | 210 | .469 | 217 | .484 | 60.3 | 5.3 | 4.87 | 4.76 |
| Ian Snell |   | sp | 26 | .778 | 583 | .322 | 379 | .464 | 388 | .475 | 108.8 | 5.2 | 4.75 | 4.58 |
| Kyle Snyder | BOS | mr | 30 | .725 | 149 | .174 | 113 | .483 | 116 | .496 | 26.3 | 4.2 | 3.82 | 3.87 |
| Andy Sonnanstine | CIN | sp | 25 | .924 | 402 | .363 | 306 | .560 | 315 | .577 | 101.1 | 7.6 | 6.94 | 6.62 |
| Joakim Soria | KCA | cl | 24 | .606 | 165 | .285 | 93 | .373 | 94 | .378 | 20.9 | 3.0 | 2.74 | 2.28 |
| Rafael Soriano | KCA | mr | 28 | .601 | 153 | .235 | 87 | .385 | 87 | .385 | 17.6 | 2.7 | 2.46 | 2.30 |
| Jorge Sosa | SFG | mr | 31 | .971 | 175 | .371 | 139 | .589 | 139 | .589 | 45.9 | 8.4 | 7.64 | 7.45 |
| Jeremy Sowers* | NYM | sp | 25 | .960 | 241 | .315 | 187 | .594 | 191 | .606 | 63.2 | 8.4 | 7.64 | 7.10 |
| Jeremy Sowers* | STL | sp | 25 | 1.410 | 28 | .429 | 31 | .912 | 32 | .941 | 15.0 | 22.4 | 19.13 | 15.92 |
| Jeremy Sowers* |   | sp | 25 | 1.006 | 269 | .327 | 218 | .625 | 223 | .639 | 76.8 | 9.4 | 8.49 | 7.78 |
| Justin Speier | SFG | mr | 34 | .710 | 152 | .250 | 90 | .431 | 94 | .450 | 23.6 | 4.2 | 3.83 | 3.32 |
| Russ Springer | BAL | mr | 39 | .598 | 128 | .266 | 75 | .357 | 80 | .381 | 16.7 | 2.9 | 2.59 | 2.53 |
| Huston Street | CWS | cl | 24 | .662 | 110 | .255 | 78 | .426 | 79 | .432 | 18.3 | 3.6 | 3.33 | 3.19 |
| Jeff Suppan | SFG | sp | 33 | .822 | 629 | .331 | 400 | .487 | 412 | .501 | 120.4 | 5.9 | 5.34 | 5.36 |
| Brian Tallet* | SFG | mr | 30 | .695 | 183 | .295 | 112 | .421 | 115 | .432 | 29.3 | 4.3 | 3.79 | 3.62 |
| Taylor Tankersley* | MIL | mr | 25 | .847 | 103 | .330 | 90 | .514 | 91 | .520 | 28.1 | 6.8 | 6.05 | 6.38 |
| Jack Taschner* | LAD | mr | 30 | .897 | 122 | .344 | 118 | .567 | 119 | .572 | 37.1 | 7.7 | 7.05 | 6.70 |
| Julian Tavarez | MIL | sp | 35 | .809 | 145 | .366 | 89 | .476 | 89 | .476 | 27.1 | 5.8 | 5.15 | 5.24 |
| Brad Thompson | LAD | mr | 26 | 1.028 | 44 | .386 | 33 | .559 | 36 | .610 | 14.4 | 11.8 | 10.28 | 9.75 |
| Matt Thornton* | CHI | mr | 31 | .463 | 12 | .250 | 5 | .250 | 6 | .300 | 1.2 | 2.0 | 1.76 | 0.99 |
| Mike Timlin | DET | mr | 42 | .588 | 165 | .248 | 71 | .335 | 74 | .349 | 17.3 | 2.9 | 2.65 | 2.48 |
| Josh Towers | CIN | sp | 31 | .779 | 291 | .299 | 182 | .468 | 189 | .486 | 50.2 | 4.9 | 4.43 | 4.39 |
| Steve Trachsel | MIL | sp | 37 | .981 | 187 | .337 | 146 | .577 | 149 | .589 | 51.3 | 9.1 | 8.21 | 8.73 |
| Derrick Turnbow | NYA | mr | 30 | .698 | 96 | .271 | 79 | .454 | 80 | .460 | 19.9 | 4.5 | 3.93 | 3.83 |
| Jose Valverde | CWS | cl | 28 | .678 | 134 | .291 | 105 | .429 | 108 | .441 | 25.1 | 3.8 | 3.38 | 3.29 |
| Rick VandenHurk | HOU | sp | 23 | .937 | 225 | .356 | 216 | .581 | 220 | .591 | 71.0 | 8.2 | 7.47 | 7.88 |
| Claudio Vargas | BAL | sp | 30 | .803 | 348 | .307 | 260 | .498 | 262 | .502 | 77.3 | 6.1 | 5.48 | 5.57 |
| Javier Vazquez | CWS | sp | 31 | .673 | 510 | .282 | 347 | .421 | 354 | .429 | 80.4 | 3.6 | 3.26 | 3.21 |
| Justin Verlander | STL | sp | 25 | .730 | 605 | .269 | 403 | .452 | 418 | .469 | 104.7 | 4.5 | 4.02 | 3.93 |
| Carlos Villanueva | STL | mr | 24 | .882 | 292 | .325 | 247 | .539 | 256 | .559 | 71.3 | 6.2 | 5.60 | 6.11 |
| Oscar Villarreal | PIT | mr | 26 | .797 | 237 | .304 | 159 | .469 | 170 | .501 | 48.6 | 5.8 | 5.09 | 4.59 |
| Ron Villone* | KCA | mr | 38 | .640 | 112 | .286 | 62 | .371 | 65 | .389 | 15.5 | 3.5 | 3.14 | 3.36 |
| Luis Vizcaino | MIN | mr | 33 | .747 | 184 | .250 | 129 | .489 | 129 | .489 | 32.3 | 4.7 | 4.29 | 3.63 |
| Billy Wagner* | NYA | cl | 36 | .704 | 129 | .326 | 100 | .444 | 101 | .449 | 25.2 | 4.2 | 3.83 | 3.50 |
| Adam Wainwright | PIT | sp | 26 | .767 | 631 | .334 | 381 | .447 | 393 | .461 | 112.6 | 5.2 | 4.74 | 4.50 |
| Tim Wakefield | CLE | sp | 41 | .821 | 316 | .297 | 214 | .507 | 215 | .509 | 58.6 | 5.3 | 4.74 | 4.85 |
| Tim Wakefield | MIN | sp | 41 | .791 | 251 | .279 | 168 | .494 | 171 | .503 | 46.0 | 5.2 | 4.76 | 4.61 |
| Tim Wakefield |   | sp | 41 | .808 | 567 | .289 | 382 | .501 | 386 | .507 | 104.6 | 5.3 | 4.75 | 4.74 |
| Jamie Walker* | BOS | mr | 36 | .710 | 188 | .282 | 105 | .422 | 108 | .434 | 29.9 | 4.8 | 4.28 | 3.76 |
| Chien-Ming Wang | CLE | sp | 28 | .652 | 636 | .267 | 318 | .390 | 324 | .398 | 76.3 | 3.5 | 3.13 | 3.09 |
| Jarrod Washburn* | BOS | sp | 33 | .872 | 567 | .309 | 430 | .546 | 435 | .552 | 127.2 | 6.5 | 5.89 | 6.03 |
| David Weathers | CIN | cl | 38 | .708 | 250 | .260 | 137 | .427 | 141 | .439 | 35.9 | 4.3 | 3.93 | 3.89 |
| Jered Weaver | PHI | sp | 25 | .684 | 497 | .270 | 287 | .417 | 291 | .423 | 73.4 | 4.0 | 3.60 | 3.39 |
| Brandon Webb | SFG | sp | 29 | .728 | 351 | .339 | 220 | .431 | 224 | .439 | 61.7 | 4.7 | 4.22 | 3.87 |
| Brandon Webb | WAS | sp | 29 | .816 | 266 | .323 | 204 | .513 | 205 | .515 | 56.7 | 5.6 | 5.07 | 5.32 |
| Brandon Webb |   | sp | 29 | .767 | 617 | .332 | 424 | .467 | 429 | .472 | 118.3 | 5.0 | 4.58 | 4.48 |
| Todd Wellemeyer | BOS | mr | 29 | .892 | 211 | .318 | 189 | .559 | 193 | .571 | 56.7 | 6.9 | 6.04 | 6.51 |
| Kip Wells | HOU | sp | 31 | .800 | 253 | .320 | 172 | .483 | 177 | .497 | 51.4 | 5.8 | 5.24 | 5.39 |
| Jake Westbrook | MIN | sp | 30 | .779 | 440 | .289 | 281 | .475 | 287 | .486 | 79.4 | 5.2 | 4.71 | 4.51 |
| Dan Wheeler | CIN | mr | 30 | .785 | 199 | .342 | 145 | .471 | 150 | .487 | 41.8 | 5.3 | 4.82 | 4.81 |
| Bob Wickman | SFG | cl | 39 | .900 | 93 | .323 | 67 | .536 | 70 | .560 | 22.9 | 7.9 | 6.94 | 6.46 |
| Woody Williams | BOS | sp | 41 | .936 | 192 | .333 | 149 | .560 | 155 | .583 | 52.2 | 8.6 | 7.83 | 7.56 |
| Dontrelle Willis* | CLE | sp | 26 | .890 | 590 | .353 | 451 | .524 | 469 | .545 | 148.0 | 7.4 | 6.59 | 6.99 |
| C.J. Wilson* | CIN | mr | 27 | .658 | 184 | .261 | 112 | .397 | 118 | .418 | 24.9 | 3.3 | 3.02 | 3.78 |
| Matt Wise | MIL | mr | 32 | .891 | 74 | .324 | 59 | .541 | 60 | .550 | 18.2 | 7.0 | 6.42 | 6.02 |
| Randy Wolf* | HOU | sp | 31 | .808 | 299 | .308 | 222 | .497 | 229 | .512 | 65.2 | 5.8 | 5.35 | 5.16 |
| Brian Wolfe | DET | mr | 27 | .770 | 75 | .240 | 47 | .490 | 47 | .490 | 12.5 | 4.9 | 4.39 | 4.09 |
| Kerry Wood | BOS | mr | 31 | .614 | 62 | .177 | 40 | .417 | 40 | .417 | 8.1 | 3.2 | 2.96 | 2.94 |
| Jamey Wright | MIL | mr | 33 | .687 | 214 | .243 | 127 | .431 | 128 | .434 | 30.4 | 4.0 | 3.57 | 3.59 |
| Michael Wuertz | LAD | mr | 29 | .830 | 192 | .370 | 156 | .506 | 158 | .513 | 46.2 | 5.9 | 5.35 | 4.88 |
| Tyler Yates | NYM | mr | 30 | .662 | 97 | .309 | 59 | .388 | 61 | .401 | 16.1 | 4.4 | 3.92 | 4.12 |
| Chris Young | CWS | sp | 29 | .654 | 446 | .267 | 290 | .411 | 293 | .416 | 69.0 | 3.7 | 3.33 | 2.97 |
| Carlos Zambrano | CAL | sp | 27 | .730 | 614 | .300 | 406 | .439 | 419 | .453 | 107.2 | 4.6 | 4.16 | 4.46 |
| Barry Zito* | PIT | sp | 30 | .701 | 609 | .274 | 357 | .436 | 359 | .438 | 92.1 | 4.3 | 3.89 | 3.54 |
| Joel Zumaya | DET | mr | 23 | .644 | 83 | .265 | 58 | .408 | 59 | .415 | 13.1 | 3.5 | 3.09 | 3.25 |
| Start |
| Name | Team | P | Age | GS | CG | CG% | SHO | QS | QS% | RS | RS/G | RL | RLS | RL% | PCH/G | STR% |
| Jeremy Accardo | CHI | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 6 | .207 | 20.0 | .617 |
| Jeremy Affeldt* | CWS | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 20.6 | .561 |
| Bronson Arroyo | SFG | sp | 31 | 31 | 0 | .000 | 0 | 13 | .419 | 169 | 5.5 | 27 | 10 | .370 | 95.7 | .640 |
| Luis Ayala | CWS | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 20.5 | .586 |
| Cha Seung Baek | NYM | sp | 28 | 10 | 0 | .000 | 0 | 2 | .200 | 32 | 3.2 | 13 | 8 | .615 | 46.5 | .650 |
| Homer Bailey | HOU | sp | 22 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 10 | .526 | 20.2 | .541 |
| Scott Baker | MIL | sp | 26 | 16 | 0 | .000 | 0 | 5 | .313 | 82 | 5.1 | 13 | 5 | .385 | 60.0 | .661 |
| John Bale* | SFG | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 25.3 | .676 |
| Brian Bannister | HOU | sp | 27 | 20 | 0 | .000 | 0 | 12 | .600 | 69 | 3.5 | 21 | 10 | .476 | 56.0 | .631 |
| Miguel Batista | PIT | sp | 37 | 6 | 0 | .000 | 0 | 5 | .833 | 36 | 6.0 | 14 | 3 | .214 | 44.4 | .608 |
| Josh Beckett | WAS | sp | 28 | 30 | 3 | .100 | 2 | 18 | .600 | 102 | 3.4 | 6 | 2 | .333 | 97.3 | .653 |
| Erik Bedard* | HOU | sp | 29 | 14 | 0 | .000 | 0 | 10 | .714 | 62 | 4.4 | 10 | 1 | .100 | 102.5 | .639 |
| Erik Bedard* | STL | sp | 29 | 14 | 0 | .000 | 0 | 7 | .500 | 78 | 5.6 | 6 | 0 | .000 | 94.1 | .637 |
| Erik Bedard* |   | sp | 29 | 28 | 0 | .000 | 0 | 17 | .607 | 140 | 5.0 | 16 | 1 | .063 | 98.4 | .638 |
| Joe Beimel* | MIN | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 6 | .250 | 16.8 | .612 |
| Matt Belisle | SFG | sp | 28 | 10 | 0 | .000 | 0 | 4 | .400 | 62 | 6.2 | 4 | 1 | .250 | 90.1 | .659 |
| Heath Bell | KCA | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 5 | .217 | 19.4 | .630 |
| Joaquin Benoit | SFG | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 23.4 | .618 |
| Jason Bergmann | SFG | sp | 26 | 6 | 0 | .000 | 0 | 2 | .333 | 35 | 5.8 | 3 | 2 | .667 | 104.5 | .611 |
| Jason Bergmann | WAS | sp | 26 | 9 | 0 | .000 | 0 | 4 | .444 | 20 | 2.2 | 0 | 0 | .000 | 103.6 | .589 |
| Jason Bergmann |   | sp | 26 | 15 | 0 | .000 | 0 | 6 | .400 | 55 | 3.7 | 3 | 2 | .667 | 103.9 | .598 |
| Rafael Betancourt | BOS | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 18.0 | .695 |
| Rafael Betancourt | MIN | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 16.7 | .708 |
| Rafael Betancourt |   | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 17.3 | .702 |
| Chad Billingsley | CLE | mr | 23 | 9 | 1 | .111 | 0 | 5 | .556 | 40 | 4.4 | 24 | 4 | .167 | 33.8 | .589 |
| Joe Blanton | DET | sp | 27 | 30 | 0 | .000 | 0 | 12 | .400 | 164 | 5.5 | 19 | 12 | .632 | 90.8 | .652 |
| Jeremy Bonderman | DET | sp | 25 | 26 | 0 | .000 | 0 | 14 | .538 | 141 | 5.4 | 12 | 4 | .333 | 88.3 | .651 |
| Boof Bonser | CIN | sp | 26 | 32 | 0 | .000 | 0 | 10 | .313 | 151 | 4.7 | 19 | 6 | .316 | 84.3 | .642 |
| Dave Borkowski | BOS | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 23.4 | .632 |
| Joe Borowski | BAL | cl | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 19.3 | .670 |
| Micah Bowie* | CWS | mr | 33 | 5 | 0 | .000 | 0 | 4 | .800 | 24 | 4.8 | 1 | 0 | .000 | 60.0 | .633 |
| Dallas Braden* | WAS | sp | 24 | 3 | 0 | .000 | 0 | 2 | .667 | 15 | 5.0 | 12 | 3 | .250 | 27.9 | .609 |
| Chad Bradford | BAL | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 9 | .563 | 17.3 | .648 |
| Doug Brocail | PIT | mr | 41 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 8 | .286 | 19.8 | .644 |
| Andrew Brown | LAD | mr | 27 | 1 | 0 | .000 | 0 | 0 | .000 | 6 | 6.0 | 11 | 5 | .455 | 23.2 | .619 |
| Jonathan Broxton | KCA | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 6 | .400 | 22.1 | .646 |
| Brian Bruney | WAS | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 26.8 | .536 |
| Taylor Buchholz | BAL | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 6 | .316 | 27.5 | .661 |
| Mark Buehrle* | CIN | sp | 29 | 13 | 2 | .154 | 1 | 9 | .692 | 86 | 6.6 | 10 | 3 | .300 | 84.5 | .646 |
| Mark Buehrle* | CLE | sp | 29 | 16 | 0 | .000 | 0 | 10 | .625 | 61 | 3.8 | 6 | 4 | .667 | 97.8 | .654 |
| Mark Buehrle* |   | sp | 29 | 29 | 2 | .069 | 1 | 19 | .655 | 147 | 5.1 | 16 | 7 | .438 | 91.3 | .650 |
| Ambiorix Burgos | MIL | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 19.6 | .599 |
| A.J. Burnett | MIL | sp | 31 | 11 | 2 | .182 | 1 | 6 | .545 | 61 | 5.5 | 5 | 1 | .200 | 100.9 | .633 |
| A.J. Burnett | NYA | sp | 31 | 12 | 0 | .000 | 0 | 5 | .417 | 84 | 7.0 | 8 | 7 | .875 | 92.7 | .612 |
| A.J. Burnett |   | sp | 31 | 23 | 2 | .087 | 1 | 11 | .478 | 145 | 6.3 | 13 | 8 | .615 | 96.8 | .623 |
| Brian Burres* | WAS | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 36.9 | .590 |
| Jared Burton | NYA | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 9 | .450 | 15.5 | .585 |
| Dave Bush | CIN | sp | 28 | 30 | 2 | .067 | 0 | 10 | .333 | 142 | 4.7 | 25 | 7 | .280 | 87.1 | .635 |
| Paul Byrd | NYM | sp | 37 | 14 | 0 | .000 | 0 | 6 | .429 | 60 | 4.3 | 9 | 4 | .444 | 83.0 | .685 |
| Tim Byrdak* | PIT | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 5 | .263 | 17.3 | .602 |
| Daniel Cabrera | WAS | sp | 27 | 29 | 5 | .172 | 0 | 13 | .448 | 109 | 3.8 | 11 | 5 | .455 | 118.7 | .587 |
| Matt Cain | LAD | sp | 23 | 18 | 0 | .000 | 0 | 12 | .667 | 81 | 4.5 | 8 | 4 | .500 | 106.8 | .595 |
| Matt Cain | CAL | sp | 23 | 12 | 0 | .000 | 0 | 5 | .417 | 42 | 3.5 | 13 | 8 | .615 | 107.4 | .593 |
| Matt Cain |   | sp | 23 | 30 | 0 | .000 | 0 | 17 | .567 | 123 | 4.1 | 21 | 12 | .571 | 107.1 | .595 |
| Kevin Cameron | CAL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 25.8 | .545 |
| Matt Capps | CWS | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 3 | .375 | 15.4 | .690 |
| Chris Capuano* | BAL | sp | 29 | 27 | 0 | .000 | 0 | 7 | .259 | 124 | 4.6 | 18 | 6 | .333 | 87.1 | .595 |
| Fausto Carmona | PIT | sp | 24 | 33 | 0 | .000 | 0 | 21 | .636 | 202 | 6.1 | 20 | 3 | .150 | 96.4 | .647 |
| Chris Carpenter | MIN | sp | 33 | 1 | 0 | .000 | 0 | 0 | .000 | 4 | 4.0 | 2 | 1 | .500 | 71.0 | .549 |
| Santiago Casilla | STL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 1 | .167 | 17.1 | .620 |
| Gustavo Chacin* | CHI | sp | 27 | 3 | 0 | .000 | 0 | 0 | .000 | 21 | 7.0 | 2 | 1 | .500 | 72.7 | .624 |
| Shawn Chacon | NYM | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 39 | 11 | .282 | 24.9 | .598 |
| Matt Chico* | BOS | sp | 25 | 12 | 1 | .083 | 0 | 3 | .250 | 60 | 5.0 | 7 | 1 | .143 | 104.0 | .571 |
| Vinnie Chulk | DET | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 3 | .231 | 19.3 | .652 |
| Roger Clemens | NYA | sp | 45 | 11 | 1 | .091 | 1 | 2 | .182 | 50 | 4.5 | 5 | 0 | .000 | 90.7 | .640 |
| Jesus Colome | CLE | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 40 | 15 | .375 | 16.1 | .589 |
| Jose Contreras | MIL | sp | 36 | 5 | 0 | .000 | 0 | 3 | .600 | 28 | 5.6 | 13 | 1 | .077 | 38.1 | .660 |
| Jose Contreras | CIN | sp | 36 | 18 | 0 | .000 | 0 | 6 | .333 | 113 | 6.3 | 14 | 0 | .000 | 85.3 | .616 |
| Jose Contreras |   | sp | 36 | 23 | 0 | .000 | 0 | 9 | .391 | 141 | 6.1 | 27 | 1 | .037 | 56.6 | .634 |
| Aaron Cook | MIN | sp | 29 | 21 | 1 | .048 | 1 | 11 | .524 | 114 | 5.4 | 19 | 4 | .211 | 65.6 | .638 |
| Chad Cordero | CLE | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 4 | .222 | 14.3 | .605 |
| Chad Cordero | DET | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 17.1 | .587 |
| Chad Cordero |   | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 5 | .172 | 15.4 | .597 |
| Francisco Cordero | NYA | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 9 | .360 | 14.5 | .617 |
| Manny Corpas | PIT | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 19.3 | .636 |
| Kevin Correia | LAD | mr | 27 | 15 | 0 | .000 | 0 | 9 | .600 | 61 | 4.1 | 15 | 6 | .400 | 72.3 | .615 |
| Neal Cotts* | CLE | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 13.9 | .581 |
| Juan Cruz | NYM | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 2 | .154 | 24.8 | .592 |
| John Danks* | BOS | sp | 23 | 19 | 0 | .000 | 0 | 6 | .316 | 88 | 4.6 | 12 | 6 | .500 | 79.2 | .633 |
| Kyle Davies | WAS | sp | 24 | 18 | 1 | .056 | 0 | 3 | .167 | 82 | 4.6 | 12 | 6 | .500 | 92.9 | .571 |
| Doug Davis* | MIL | sp | 32 | 28 | 0 | .000 | 0 | 11 | .393 | 117 | 4.2 | 25 | 12 | .480 | 80.8 | .593 |
| Jorge De La Rosa* | NYM | sp | 27 | 1 | 0 | .000 | 0 | 1 | 1.000 | 4 | 4.0 | 0 | 0 | .000 | 108.0 | .694 |
| Manny Delcarmen | KCA | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 0 | .000 | 20.8 | .579 |
| Ryan Dempster | BAL | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 5 | .333 | 19.1 | .596 |
| Lenny DiNardo* | NYM | sp | 28 | 12 | 0 | .000 | 0 | 5 | .417 | 66 | 5.5 | 15 | 7 | .467 | 40.6 | .623 |
| Brendan Donnelly | BOS | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 6 | .750 | 19.6 | .602 |
| Scott Downs* | NYM | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 19.0 | .612 |
| Brandon Duckworth | CLE | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 | 13.8 | .552 |
| Zach Duke* | CHI | sp | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 9 | .391 | 24.4 | .638 |
| Chad Durbin | NYM | sp | 30 | 19 | 0 | .000 | 0 | 6 | .316 | 98 | 5.2 | 8 | 1 | .125 | 67.1 | .627 |
| J.D. Durbin | WAS | sp | 26 | 2 | 0 | .000 | 0 | 2 | 1.000 | 6 | 3.0 | 7 | 2 | .286 | 27.3 | .588 |
| Alan Embree* | BOS | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 4 | .200 | 14.0 | .660 |
| Alan Embree* | MIN | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 16.3 | .662 |
| Alan Embree* |   | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 29 | 7 | .241 | 14.8 | .661 |
| Kelvim Escobar | NYA | sp | 32 | 31 | 1 | .032 | 1 | 20 | .645 | 164 | 5.3 | 12 | 4 | .333 | 94.9 | .616 |
| Kyle Farnsworth | CLE | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 8 | .421 | 17.3 | .616 |
| Pedro Feliciano* | STL | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 5 | .208 | 16.2 | .570 |
| Josh Fogg | SFG | sp | 31 | 11 | 0 | .000 | 0 | 2 | .182 | 55 | 5.0 | 8 | 3 | .375 | 88.1 | .609 |
| Jeff Francis* | DET | sp | 27 | 30 | 0 | .000 | 0 | 21 | .700 | 155 | 5.2 | 15 | 6 | .400 | 96.0 | .623 |
| Frank Francisco | PHI | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 7 | .368 | 21.0 | .584 |
| Ryan Franklin | CWS | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 0 | .000 | 21.4 | .649 |
| Jason Frasor | SFG | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 4 | .250 | 24.3 | .613 |
| Brian Fuentes* | LAD | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 18.1 | .542 |
| Brian Fuentes* | NYA | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 12 | .375 | 12.7 | .554 |
| Brian Fuentes* |   | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 40 | 14 | .350 | 13.8 | .551 |
| Aaron Fultz* | CAL | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 5 | .152 | 13.2 | .583 |
| Kason Gabbard* | CAL | sp | 26 | 12 | 0 | .000 | 0 | 8 | .667 | 58 | 4.8 | 8 | 2 | .250 | 103.0 | .595 |
| Eric Gagne | MIL | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 3 | .600 | 21.8 | .555 |
| Eric Gagne | BOS | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 23.2 | .551 |
| Eric Gagne |   | cl | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 4 | .333 | 22.2 | .554 |
| Yovani Gallardo | MIL | sp | 22 | 9 | 0 | .000 | 0 | 3 | .333 | 50 | 5.6 | 8 | 4 | .500 | 99.6 | .616 |
| Yovani Gallardo | PIT | sp | 22 | 4 | 0 | .000 | 0 | 1 | .250 | 15 | 3.8 | 3 | 1 | .333 | 107.3 | .601 |
| Yovani Gallardo |   | sp | 22 | 13 | 0 | .000 | 0 | 4 | .308 | 65 | 5.0 | 11 | 5 | .455 | 101.9 | .611 |
| Lee Gardner | PIT | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 5 | .179 | 18.0 | .647 |
| Jon Garland | KCA | sp | 28 | 28 | 0 | .000 | 0 | 16 | .571 | 153 | 5.5 | 10 | 4 | .400 | 97.6 | .653 |
| Matt Garza | CAL | sp | 24 | 12 | 1 | .083 | 0 | 6 | .500 | 46 | 3.8 | 4 | 0 | .000 | 107.3 | .632 |
| Chad Gaudin | CIN | sp | 25 | 15 | 0 | .000 | 0 | 3 | .200 | 60 | 4.0 | 11 | 3 | .273 | 82.6 | .604 |
| Chad Gaudin | STL | sp | 25 | 13 | 0 | .000 | 0 | 6 | .462 | 65 | 5.0 | 6 | 3 | .500 | 89.3 | .599 |
| Chad Gaudin |   | sp | 25 | 28 | 0 | .000 | 0 | 9 | .321 | 125 | 4.5 | 17 | 6 | .353 | 85.9 | .602 |
| Geoff Geary | BOS | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 18.0 | .648 |
| Justin Germano | CAL | sp | 25 | 19 | 2 | .105 | 0 | 10 | .526 | 65 | 3.4 | 7 | 2 | .286 | 103.2 | .642 |
| Tom Glavine* | LAD | sp | 42 | 32 | 0 | .000 | 0 | 16 | .500 | 140 | 4.4 | 20 | 6 | .300 | 90.9 | .624 |
| Jimmy Gobble* | PHI | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 8 | .296 | 11.5 | .604 |
| Edgar Gonzalez | CWS | mr | 25 | 2 | 0 | .000 | 0 | 1 | .500 | 7 | 3.5 | 3 | 1 | .333 | 42.2 | .611 |
| Tom Gorzelanny* | PIT | sp | 25 | 25 | 1 | .040 | 0 | 10 | .400 | 137 | 5.5 | 11 | 4 | .364 | 94.7 | .612 |
| John Grabow* | NYM | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 20.4 | .642 |
| Sean Green | MIL | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 10 | .370 | 22.5 | .565 |
| Kevin Gregg | CAL | cl | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 22.8 | .554 |
| Zack Greinke | CHI | mr | 24 | 18 | 1 | .056 | 1 | 7 | .389 | 94 | 5.2 | 12 | 4 | .333 | 92.4 | .665 |
| Jason Grilli | SFG | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 5 | .455 | 23.7 | .606 |
| Matt Guerrier | PHI | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 3 | .158 | 16.7 | .648 |
| Jeremy Guthrie | CHI | sp | 29 | 27 | 1 | .037 | 1 | 15 | .556 | 138 | 5.1 | 11 | 1 | .091 | 90.6 | .646 |
| Roy Halladay | NYA | sp | 31 | 34 | 2 | .059 | 2 | 24 | .706 | 209 | 6.1 | 20 | 11 | .550 | 95.4 | .661 |
| Cole Hamels* | MIN | sp | 24 | 29 | 1 | .034 | 1 | 14 | .483 | 164 | 5.7 | 14 | 2 | .143 | 95.2 | .648 |
| Jason Hammel | NYM | sp | 25 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 2 | 0 | .000 | 97.0 | .598 |
| Justin Hampson* | CWS | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 12 | .444 | 16.9 | .618 |
| Joel Hanrahan | PHI | sp | 26 | 9 | 0 | .000 | 0 | 0 | .000 | 44 | 4.9 | 4 | 0 | .000 | 88.2 | .548 |
| Aaron Harang | STL | sp | 30 | 34 | 6 | .176 | 1 | 20 | .588 | 202 | 5.9 | 9 | 4 | .444 | 104.1 | .660 |
| Rich Harden | WAS | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 4 | 1.000 | 23.4 | .578 |
| Dan Haren | LAD | sp | 27 | 18 | 1 | .056 | 1 | 14 | .778 | 67 | 3.7 | 12 | 5 | .417 | 101.1 | .668 |
| Dan Haren | CAL | sp | 27 | 15 | 1 | .067 | 0 | 9 | .600 | 56 | 3.7 | 9 | 7 | .778 | 108.0 | .630 |
| Dan Haren |   | sp | 27 | 33 | 2 | .061 | 1 | 23 | .697 | 123 | 3.7 | 21 | 12 | .571 | 104.2 | .650 |
| LaTroy Hawkins | SFG | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 4 | .444 | 20.5 | .615 |
| Aaron Heilman | LAD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 17.3 | .622 |
| Mark Hendrickson* | WAS | mr | 34 | 2 | 0 | .000 | 0 | 1 | .500 | 4 | 2.0 | 15 | 2 | .133 | 30.4 | .619 |
| Brad Hennessey | PHI | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 8 | .400 | 19.8 | .603 |
| Matt Herges | NYA | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 4 | .400 | 15.0 | .596 |
| Felix Hernandez | DET | sp | 22 | 26 | 0 | .000 | 0 | 12 | .462 | 128 | 4.9 | 18 | 7 | .389 | 97.4 | .640 |
| Livan Hernandez | BOS | sp | 33 | 17 | 0 | .000 | 0 | 9 | .529 | 114 | 6.7 | 11 | 5 | .455 | 89.4 | .594 |
| Orlando Hernandez | NYM | sp | 38 | 23 | 1 | .043 | 1 | 15 | .652 | 109 | 4.7 | 10 | 4 | .400 | 95.0 | .602 |
| Rich Hill* | BAL | sp | 28 | 32 | 2 | .063 | 2 | 16 | .500 | 113 | 3.5 | 26 | 10 | .385 | 93.6 | .620 |
| Shawn Hill | LAD | sp | 27 | 14 | 0 | .000 | 0 | 8 | .571 | 64 | 4.6 | 7 | 2 | .286 | 91.6 | .624 |
| Jason Hirsh | CHI | sp | 26 | 18 | 1 | .056 | 1 | 7 | .389 | 89 | 4.9 | 13 | 4 | .308 | 78.0 | .619 |
| Trevor Hoffman | BAL | cl | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 1 | .250 | 17.8 | .645 |
| J.P. Howell* | CIN | sp | 25 | 9 | 0 | .000 | 0 | 3 | .333 | 63 | 7.0 | 6 | 1 | .167 | 64.0 | .631 |
| Bob Howry | CIN | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 6 | .300 | 19.4 | .651 |
| Tim Hudson | PHI | sp | 32 | 13 | 2 | .154 | 1 | 11 | .846 | 75 | 5.8 | 11 | 4 | .364 | 105.5 | .651 |
| Tim Hudson | KCA | sp | 32 | 18 | 1 | .056 | 1 | 13 | .722 | 112 | 6.2 | 14 | 2 | .143 | 93.7 | .646 |
| Tim Hudson |   | sp | 32 | 31 | 3 | .097 | 2 | 24 | .774 | 187 | 6.0 | 25 | 6 | .240 | 98.6 | .648 |
| Phil Hughes | CIN | sp | 22 | 4 | 0 | .000 | 0 | 1 | .250 | 17 | 4.3 | 1 | 0 | .000 | 88.5 | .641 |
| Phil Hughes | CLE | sp | 22 | 8 | 0 | .000 | 0 | 7 | .875 | 25 | 3.1 | 7 | 3 | .429 | 93.9 | .602 |
| Phil Hughes |   | sp | 22 | 12 | 0 | .000 | 0 | 8 | .667 | 42 | 3.5 | 8 | 3 | .375 | 92.1 | .614 |
| Jason Isringhausen | STL | cl | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 15.7 | .605 |
| Edwin Jackson | MIL | sp | 24 | 23 | 0 | .000 | 0 | 7 | .304 | 93 | 4.0 | 22 | 8 | .364 | 67.9 | .596 |
| Chuck James* | KCA | sp | 26 | 16 | 0 | .000 | 0 | 9 | .563 | 90 | 5.6 | 16 | 7 | .438 | 90.4 | .624 |
| Casey Janssen | HOU | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 18.1 | .655 |
| Casey Janssen | STL | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 18.7 | .643 |
| Casey Janssen |   | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 1 | .063 | 18.3 | .650 |
| Bobby Jenks | DET | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 3 | .300 | 15.3 | .649 |
| Jason Jennings | PIT | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 31.0 | .581 |
| Ubaldo Jimenez | LAD | sp | 24 | 3 | 0 | .000 | 0 | 2 | .667 | 18 | 6.0 | 3 | 2 | .667 | 63.2 | .601 |
| Ubaldo Jimenez | CAL | sp | 24 | 9 | 0 | .000 | 0 | 7 | .778 | 51 | 5.7 | 7 | 3 | .429 | 115.0 | .596 |
| Ubaldo Jimenez |   | sp | 24 | 12 | 0 | .000 | 0 | 9 | .750 | 69 | 5.8 | 10 | 5 | .500 | 96.5 | .597 |
| Josh Johnson | MIL | sp | 24 | 5 | 0 | .000 | 0 | 1 | .200 | 30 | 6.0 | 8 | 2 | .250 | 61.2 | .618 |
| Randy Johnson* | KCA | sp | 44 | 6 | 0 | .000 | 0 | 3 | .500 | 26 | 4.3 | 8 | 4 | .500 | 42.4 | .656 |
| Tyler Johnson* | STL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 3 | .143 | 12.0 | .650 |
| Todd Jones | CIN | cl | 40 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 17.4 | .616 |
| Jorge Julio | BAL | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 5 | .278 | 20.7 | .568 |
| Scott Kazmir* | CIN | sp | 24 | 17 | 0 | .000 | 0 | 5 | .294 | 49 | 2.9 | 17 | 11 | .647 | 92.6 | .592 |
| Scott Kazmir* | CLE | sp | 24 | 16 | 1 | .063 | 1 | 8 | .500 | 75 | 4.7 | 9 | 6 | .667 | 110.3 | .614 |
| Scott Kazmir* |   | sp | 24 | 33 | 1 | .030 | 1 | 13 | .394 | 124 | 3.8 | 26 | 17 | .654 | 101.2 | .604 |
| Kyle Kendrick | MIL | sp | 23 | 15 | 1 | .067 | 0 | 6 | .400 | 70 | 4.7 | 1 | 0 | .000 | 90.0 | .664 |
| Joe Kennedy* | LAD | mr | 29 | 2 | 1 | .500 | 0 | 0 | .000 | 7 | 3.5 | 2 | 0 | .000 | 67.0 | .642 |
| Logan Kensing | PIT | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 25.3 | .664 |
| Ray King* | NYM | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 17.7 | .588 |
| John Lackey | KCA | sp | 29 | 33 | 1 | .030 | 1 | 23 | .697 | 203 | 6.2 | 21 | 8 | .381 | 97.0 | .649 |
| Aaron Laffey* | HOU | sp | 23 | 3 | 0 | .000 | 0 | 2 | .667 | 12 | 4.0 | 1 | 0 | .000 | 44.0 | .672 |
| Aaron Laffey* | STL | sp | 23 | 4 | 0 | .000 | 0 | 1 | .250 | 17 | 4.3 | 5 | 0 | .000 | 74.8 | .632 |
| Aaron Laffey* |   | sp | 23 | 7 | 0 | .000 | 0 | 3 | .429 | 29 | 4.1 | 6 | 0 | .000 | 53.5 | .655 |
| John Lannan* | SFG | sp | 23 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 1 | 0 | .000 | 93.0 | .591 |
| John Lannan* | WAS | sp | 23 | 3 | 0 | .000 | 0 | 0 | .000 | 10 | 3.3 | 2 | 0 | .000 | 68.7 | .546 |
| John Lannan* |   | sp | 23 | 4 | 0 | .000 | 0 | 0 | .000 | 15 | 3.8 | 3 | 0 | .000 | 72.1 | .554 |
| Brandon League | WAS | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 1 | 0 | .000 | 15.9 | .622 |
| Cliff Lee* | PHI | sp | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 32 | 14 | .438 | 23.7 | .612 |
| Jon Lester* | HOU | sp | 24 | 2 | 0 | .000 | 0 | 1 | .500 | 5 | 2.5 | 15 | 4 | .267 | 24.3 | .613 |
| Brad Lidge | PHI | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 1 | .125 | 15.4 | .621 |
| Jon Lieber | PHI | sp | 38 | 14 | 0 | .000 | 0 | 6 | .429 | 66 | 4.7 | 9 | 1 | .111 | 93.2 | .654 |
| Ted Lilly* | SFG | sp | 32 | 31 | 1 | .032 | 0 | 12 | .387 | 160 | 5.2 | 9 | 1 | .111 | 94.6 | .639 |
| Tim Lincecum | WAS | sp | 24 | 23 | 1 | .043 | 0 | 13 | .565 | 83 | 3.6 | 6 | 2 | .333 | 104.2 | .600 |
| Matt Lindstrom | CAL | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 3 | .250 | 21.5 | .635 |
| Scott Linebrink | CLE | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 7 | .259 | 17.4 | .614 |
| Jesse Litsch | LAD | sp | 23 | 4 | 0 | .000 | 0 | 2 | .500 | 18 | 4.5 | 4 | 3 | .750 | 81.5 | .644 |
| Jesse Litsch | CAL | sp | 23 | 14 | 0 | .000 | 0 | 11 | .786 | 60 | 4.3 | 7 | 3 | .429 | 91.6 | .626 |
| Jesse Litsch |   | sp | 23 | 18 | 0 | .000 | 0 | 13 | .722 | 78 | 4.3 | 11 | 6 | .545 | 89.4 | .630 |
| Wes Littleton | LAD | mr | 25 | 3 | 0 | .000 | 0 | 1 | .333 | 12 | 4.0 | 5 | 1 | .200 | 32.9 | .580 |
| Kameron Loe | NYM | sp | 26 | 2 | 0 | .000 | 0 | 1 | .500 | 18 | 9.0 | 1 | 0 | .000 | 103.5 | .580 |
| Adam Loewen* | NYM | sp | 24 | 6 | 0 | .000 | 0 | 2 | .333 | 24 | 4.0 | 7 | 2 | .286 | 108.0 | .522 |
| Boone Logan* | NYM | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 7 | .333 | 22.1 | .627 |
| Kyle Lohse | MIN | sp | 29 | 30 | 0 | .000 | 0 | 16 | .533 | 167 | 5.6 | 22 | 8 | .364 | 88.6 | .632 |
| Braden Looper | CAL | sp | 33 | 25 | 5 | .200 | 0 | 12 | .480 | 94 | 3.8 | 10 | 3 | .300 | 111.2 | .613 |
| Javier Lopez* | LAD | mr | 30 | 8 | 0 | .000 | 0 | 1 | .125 | 27 | 3.4 | 8 | 0 | .000 | 42.9 | .554 |
| Rodrigo Lopez | STL | sp | 32 | 13 | 1 | .077 | 0 | 6 | .462 | 94 | 7.2 | 9 | 5 | .556 | 88.7 | .648 |
| Derek Lowe | CWS | sp | 35 | 29 | 1 | .034 | 1 | 16 | .552 | 132 | 4.6 | 21 | 4 | .190 | 101.0 | .621 |
| Noah Lowry* | CAL | sp | 27 | 12 | 1 | .083 | 0 | 3 | .250 | 71 | 5.9 | 11 | 4 | .364 | 118.4 | .573 |
| Brandon Lyon | MIN | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 6 | .286 | 18.1 | .603 |
| Greg Maddux | BAL | sp | 42 | 30 | 0 | .000 | 0 | 15 | .500 | 136 | 4.5 | 12 | 2 | .167 | 91.5 | .685 |
| Ryan Madson | CAL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 6 | .600 | 23.9 | .590 |
| Ron Mahay* | CAL | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 4 | .211 | 20.2 | .579 |
| Paul Maholm* | PHI | sp | 26 | 30 | 2 | .067 | 0 | 8 | .267 | 172 | 5.7 | 15 | 2 | .133 | 81.4 | .620 |
| John Maine | PHI | sp | 27 | 31 | 1 | .032 | 0 | 11 | .355 | 173 | 5.6 | 29 | 10 | .345 | 95.3 | .618 |
| Shaun Marcum | CHI | sp | 26 | 25 | 0 | .000 | 0 | 11 | .440 | 151 | 6.0 | 24 | 6 | .250 | 93.7 | .644 |
| Carlos Marmol | CHI | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 10 | .303 | 17.9 | .573 |
| Jason Marquis | HOU | sp | 29 | 29 | 5 | .172 | 4 | 14 | .483 | 141 | 4.9 | 31 | 16 | .516 | 90.3 | .621 |
| Sean Marshall* | NYM | sp | 25 | 19 | 0 | .000 | 0 | 5 | .263 | 96 | 5.1 | 6 | 3 | .500 | 85.4 | .624 |
| Damaso Marte* | MIL | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 7 | .389 | 18.6 | .629 |
| Pedro Martinez | NYA | sp | 36 | 5 | 0 | .000 | 0 | 1 | .200 | 30 | 6.0 | 3 | 2 | .667 | 72.2 | .673 |
| Daisuke Matsuzaka | DET | sp | 27 | 30 | 0 | .000 | 0 | 12 | .400 | 176 | 5.9 | 18 | 3 | .167 | 98.0 | .616 |
| Brandon McCarthy | DET | sp | 24 | 8 | 0 | .000 | 0 | 4 | .500 | 45 | 5.6 | 27 | 7 | .259 | 46.3 | .559 |
| Dustin McGowan | NYA | sp | 26 | 26 | 2 | .077 | 1 | 15 | .577 | 180 | 6.9 | 9 | 6 | .667 | 99.6 | .630 |
| Gil Meche | CHI | sp | 29 | 32 | 1 | .031 | 1 | 22 | .688 | 182 | 5.7 | 19 | 6 | .316 | 96.9 | .647 |
| Cla Meredith | DET | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 3 | .143 | 15.7 | .652 |
| Andrew Miller* | HOU | sp | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 5 | .313 | 23.3 | .583 |
| Justin Miller | HOU | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 21.0 | .624 |
| Trever Miller* | BOS | mr | 35 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 17.3 | .578 |
| Kevin Millwood | BAL | sp | 33 | 30 | 2 | .067 | 2 | 17 | .567 | 121 | 4.0 | 21 | 10 | .476 | 94.8 | .624 |
| Zach Miner | KCA | mr | 26 | 8 | 0 | .000 | 0 | 5 | .625 | 61 | 7.6 | 5 | 2 | .400 | 62.5 | .630 |
| Sergio Mitre | PHI | sp | 27 | 23 | 2 | .087 | 0 | 10 | .435 | 137 | 6.0 | 21 | 6 | .286 | 86.4 | .623 |
| Brian Moehler | NYM | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 2 | .500 | 28.8 | .652 |
| Franklin Morales* | BOS | sp | 22 | 4 | 1 | .250 | 0 | 2 | .500 | 12 | 3.0 | 3 | 1 | .333 | 89.0 | .604 |
| Matt Morris | NYM | sp | 33 | 32 | 1 | .031 | 0 | 13 | .406 | 148 | 4.6 | 16 | 6 | .375 | 84.9 | .623 |
| Brandon Morrow | NYM | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 15 | .556 | 23.8 | .550 |
| Dustin Moseley | NYA | mr | 26 | 10 | 2 | .200 | 2 | 7 | .700 | 74 | 7.4 | 11 | 2 | .182 | 81.2 | .652 |
| Guillermo Mota | CLE | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 4 | .364 | 22.7 | .629 |
| Jamie Moyer* | BOS | sp | 45 | 31 | 1 | .032 | 0 | 8 | .258 | 115 | 3.7 | 24 | 13 | .542 | 85.9 | .605 |
| Peter Moylan | PIT | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 | 17.8 | .635 |
| Mike Mussina | CLE | sp | 39 | 25 | 1 | .040 | 0 | 13 | .520 | 105 | 4.2 | 15 | 4 | .267 | 82.9 | .668 |
| Brett Myers | LAD | cl | 27 | 11 | 0 | .000 | 0 | 4 | .364 | 50 | 4.5 | 10 | 7 | .700 | 81.8 | .595 |
| Joe Nathan | MIL | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 17.0 | .640 |
| Joe Nathan | MIN | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 1 | .143 | 19.5 | .624 |
| Joe Nathan |   | cl | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 1 | .100 | 18.0 | .633 |
| Pat Neshek | CIN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 20.5 | .645 |
| Pat Neshek | STL | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 4 | 0 | .000 | 16.6 | .655 |
| Pat Neshek |   | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 3 | .273 | 18.8 | .649 |
| Dustin Nippert | CWS | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 3 | .429 | 14.0 | .543 |
| Leo Nunez | CWS | mr | 24 | 3 | 1 | .333 | 0 | 2 | .667 | 17 | 5.7 | 4 | 3 | .750 | 49.0 | .637 |
| Eric O'Flaherty* | PHI | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 5 | .192 | 14.8 | .624 |
| Hideki Okajima* | CHI | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 0 | .000 | 20.3 | .672 |
| Darren Oliver* | BAL | mr | 37 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 6 | .545 | 21.5 | .606 |
| Scott Olsen* | MIL | sp | 24 | 5 | 0 | .000 | 0 | 0 | .000 | 29 | 5.8 | 12 | 0 | .000 | 42.0 | .609 |
| Scott Olsen* | WAS | sp | 24 | 17 | 0 | .000 | 0 | 5 | .294 | 66 | 3.9 | 13 | 5 | .385 | 102.4 | .570 |
| Scott Olsen* |   | sp | 24 | 22 | 0 | .000 | 0 | 5 | .227 | 95 | 4.3 | 25 | 5 | .200 | 67.7 | .584 |
| Garrett Olson* | WAS | sp | 24 | 5 | 0 | .000 | 0 | 0 | .000 | 25 | 5.0 | 14 | 3 | .214 | 50.1 | .546 |
| Ramon Ortiz | LAD | mr | 35 | 1 | 0 | .000 | 0 | 1 | 1.000 | 3 | 3.0 | 2 | 1 | .500 | 48.0 | .667 |
| Roy Oswalt | CWS | sp | 30 | 29 | 3 | .103 | 1 | 16 | .552 | 122 | 4.2 | 14 | 5 | .357 | 101.9 | .621 |
| Akinori Otsuka | NYA | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 17.4 | .601 |
| Micah Owings | MIN | sp | 25 | 23 | 0 | .000 | 0 | 11 | .478 | 137 | 6.0 | 26 | 12 | .462 | 76.4 | .602 |
| Vicente Padilla | BOS | sp | 30 | 12 | 0 | .000 | 0 | 2 | .167 | 58 | 4.8 | 10 | 2 | .200 | 71.9 | .597 |
| Vicente Padilla | MIN | sp | 30 | 3 | 0 | .000 | 0 | 1 | .333 | 12 | 4.0 | 13 | 1 | .077 | 30.4 | .641 |
| Vicente Padilla |   | sp | 30 | 15 | 0 | .000 | 0 | 3 | .200 | 70 | 4.7 | 23 | 3 | .130 | 47.7 | .613 |
| Jonathan Papelbon | NYA | cl | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 1 | .200 | 16.1 | .627 |
| Chad Paronto | MIL | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 5 | .714 | 16.4 | .558 |
| John Patterson | CWS | sp | 30 | 4 | 1 | .250 | 1 | 1 | .250 | 17 | 4.3 | 0 | 0 | .000 | 91.3 | .559 |
| Jake Peavy | CHI | sp | 27 | 31 | 3 | .097 | 1 | 23 | .742 | 170 | 5.5 | 8 | 2 | .250 | 104.3 | .656 |
| Mike Pelfrey | MIL | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 5 | 5.0 | 17 | 4 | .235 | 25.7 | .557 |
| Tony Pena | STL | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 6 | .261 | 18.0 | .603 |
| Brad Penny | SFG | sp | 30 | 18 | 0 | .000 | 0 | 9 | .500 | 103 | 5.7 | 14 | 5 | .357 | 96.3 | .597 |
| Brad Penny | DET | sp | 30 | 12 | 0 | .000 | 0 | 7 | .583 | 69 | 5.8 | 7 | 4 | .571 | 91.8 | .608 |
| Brad Penny |   | sp | 30 | 30 | 0 | .000 | 0 | 16 | .533 | 172 | 5.7 | 21 | 9 | .429 | 94.5 | .601 |
| Joel Peralta | BAL | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 3 | .231 | 22.2 | .671 |
| Troy Percival | CHI | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 1 | .071 | 15.6 | .642 |
| Odalis Perez* | LAD | sp | 31 | 2 | 0 | .000 | 0 | 1 | .500 | 8 | 4.0 | 0 | 0 | .000 | 96.3 | .564 |
| Oliver Perez* | MIL | sp | 26 | 18 | 0 | .000 | 0 | 5 | .278 | 102 | 5.7 | 11 | 7 | .636 | 105.7 | .580 |
| Oliver Perez* | CLE | sp | 26 | 9 | 0 | .000 | 0 | 6 | .667 | 29 | 3.2 | 7 | 3 | .429 | 101.5 | .600 |
| Oliver Perez* |   | sp | 26 | 27 | 0 | .000 | 0 | 11 | .407 | 131 | 4.9 | 18 | 10 | .556 | 104.2 | .587 |
| Rafael Perez* | KCA | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 4 | .190 | 17.0 | .635 |
| Yusmeiro Petit | WAS | sp | 23 | 3 | 0 | .000 | 0 | 1 | .333 | 18 | 6.0 | 3 | 1 | .333 | 22.4 | .655 |
| Andy Pettitte* | PIT | sp | 36 | 31 | 2 | .065 | 1 | 17 | .548 | 146 | 4.7 | 20 | 5 | .250 | 97.6 | .637 |
| Joel Pineiro | MIN | mr | 29 | 7 | 0 | .000 | 0 | 2 | .286 | 21 | 3.0 | 17 | 4 | .235 | 33.5 | .621 |
| Renyel Pinto* | DET | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 8 | .308 | 13.8 | .567 |
| Scott Proctor | LAD | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 28 | 10 | .357 | 22.8 | .592 |
| J.J. Putz | CHI | cl | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 1 | .500 | 15.5 | .638 |
| Chad Qualls | MIN | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 2 | .105 | 22.2 | .633 |
| Jon Rauch | LAD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 24 | 11 | .458 | 18.9 | .626 |
| Jon Rauch | NYA | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 7 | 2 | .286 | 18.2 | .683 |
| Jon Rauch |   | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 31 | 13 | .419 | 18.7 | .635 |
| Chris Ray | DET | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 2 | .182 | 23.4 | .599 |
| Tim Redding | STL | sp | 30 | 14 | 0 | .000 | 0 | 2 | .143 | 103 | 7.4 | 16 | 9 | .563 | 92.6 | .593 |
| Al Reyes | CIN | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 9 | .529 | 19.8 | .624 |
| Anthony Reyes | MIN | sp | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 6 | .429 | 24.7 | .621 |
| Jo-Jo Reyes* | WAS | sp | 23 | 4 | 0 | .000 | 0 | 2 | .500 | 27 | 6.8 | 3 | 2 | .667 | 56.0 | .547 |
| John Rheinecker* | NYM | mr | 29 | 9 | 0 | .000 | 0 | 4 | .444 | 38 | 4.2 | 9 | 3 | .333 | 53.0 | .599 |
| Juan Rincon | STL | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 1 | .091 | 17.2 | .627 |
| David Riske | CAL | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 6 | .353 | 18.0 | .616 |
| Mariano Rivera | NYA | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 25 | 4 | .160 | 16.1 | .673 |
| Saul Rivera | CWS | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 10 | 5 | .500 | 23.4 | .607 |
| Nate Robertson* | HOU | sp | 30 | 29 | 1 | .034 | 1 | 13 | .448 | 105 | 3.6 | 19 | 9 | .474 | 87.5 | .630 |
| Fernando Rodney | CHI | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 5 | .250 | 14.7 | .625 |
| Francisco Rodriguez | SFG | cl | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 19.8 | .613 |
| Wandy Rodriguez* | LAD | sp | 29 | 28 | 0 | .000 | 0 | 16 | .571 | 154 | 5.5 | 21 | 6 | .286 | 102.5 | .629 |
| Kenny Rogers* | CHI | sp | 43 | 8 | 0 | .000 | 0 | 5 | .625 | 31 | 3.9 | 8 | 1 | .125 | 81.9 | .621 |
| J.C. Romero* | CLE | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 47 | 11 | .234 | 13.3 | .550 |
| Ryan Rowland-Smith* | WAS | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 2 | 0 | .000 | 21.3 | .595 |
| C.C. Sabathia* | NYA | sp | 27 | 33 | 4 | .121 | 1 | 18 | .545 | 206 | 6.2 | 10 | 5 | .500 | 102.8 | .686 |
| Takashi Saito | SFG | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 1 | .333 | 18.7 | .662 |
| Juan Salas | NYM | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 18.9 | .620 |
| Chris Sampson | BOS | sp | 30 | 3 | 1 | .333 | 0 | 0 | .000 | 7 | 2.3 | 20 | 8 | .400 | 32.5 | .609 |
| Anibal Sanchez | CAL | sp | 24 | 1 | 0 | .000 | 0 | 0 | .000 | 1 | 1.0 | 6 | 0 | .000 | 44.0 | .558 |
| Jonathan Sanchez* | HOU | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 4 | .286 | 20.0 | .585 |
| Ervin Santana | HOU | sp | 25 | 24 | 0 | .000 | 0 | 9 | .375 | 118 | 4.9 | 16 | 1 | .063 | 68.9 | .621 |
| Johan Santana* | KCA | sp | 29 | 33 | 4 | .121 | 0 | 22 | .667 | 187 | 5.7 | 7 | 0 | .000 | 96.4 | .659 |
| Joe Saunders* | PHI | sp | 27 | 16 | 1 | .063 | 0 | 6 | .375 | 90 | 5.6 | 14 | 7 | .500 | 89.6 | .633 |
| Curt Schilling | BAL | sp | 41 | 23 | 0 | .000 | 0 | 11 | .478 | 98 | 4.3 | 11 | 1 | .091 | 92.3 | .667 |
| Scott Schoeneweis* | BOS | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 21.0 | .655 |
| Chris Schroder | CLE | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 8 | .533 | 21.6 | .619 |
| Rudy Seanez | BOS | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 6 | .667 | 26.0 | .595 |
| Bobby Seay* | DET | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 6 | .333 | 12.6 | .629 |
| Ben Sheets | KCA | sp | 29 | 20 | 0 | .000 | 0 | 15 | .750 | 117 | 5.8 | 9 | 6 | .667 | 98.2 | .643 |
| George Sherrill* | CHI | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 3 | .167 | 13.6 | .610 |
| James Shields | CWS | sp | 26 | 31 | 1 | .032 | 1 | 17 | .548 | 136 | 4.4 | 15 | 4 | .267 | 97.9 | .671 |
| Scot Shields | PHI | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 3 | .136 | 17.4 | .599 |
| Brian Shouse* | DET | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 4 | .200 | 13.9 | .629 |
| Carlos Silva | BOS | sp | 29 | 18 | 0 | .000 | 0 | 12 | .667 | 86 | 4.8 | 14 | 7 | .500 | 93.4 | .655 |
| Carlos Silva | MIN | sp | 29 | 13 | 1 | .077 | 1 | 8 | .615 | 67 | 5.2 | 5 | 0 | .000 | 88.0 | .677 |
| Carlos Silva |   | sp | 29 | 31 | 1 | .032 | 1 | 20 | .645 | 153 | 4.9 | 19 | 7 | .368 | 91.2 | .664 |
| Doug Slaten* | NYM | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 7 | .438 | 15.8 | .578 |
| Kevin Slowey | BOS | sp | 24 | 12 | 0 | .000 | 0 | 5 | .417 | 52 | 4.3 | 3 | 1 | .333 | 88.8 | .661 |
| Joe Smith | CIN | mr | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 33 | 11 | .333 | 18.0 | .585 |
| John Smoltz | STL | sp | 41 | 31 | 2 | .065 | 0 | 18 | .581 | 188 | 6.1 | 10 | 5 | .500 | 98.4 | .650 |
| Ian Snell | MIL | sp | 26 | 12 | 0 | .000 | 0 | 4 | .333 | 46 | 3.8 | 0 | 0 | .000 | 69.9 | .622 |
| Ian Snell | HOU | sp | 26 | 16 | 0 | .000 | 0 | 7 | .438 | 66 | 4.1 | 14 | 3 | .214 | 100.4 | .626 |
| Ian Snell |   | sp | 26 | 28 | 0 | .000 | 0 | 11 | .393 | 112 | 4.0 | 14 | 3 | .214 | 83.9 | .625 |
| Kyle Snyder | BOS | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 19 | 1 | .053 | 18.7 | .580 |
| Andy Sonnanstine | CIN | sp | 25 | 22 | 0 | .000 | 0 | 7 | .318 | 118 | 5.4 | 16 | 5 | .313 | 86.0 | .664 |
| Joakim Soria | KCA | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 3 | 0 | .000 | 16.9 | .646 |
| Rafael Soriano | KCA | mr | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 3 | .176 | 16.0 | .662 |
| Jorge Sosa | SFG | mr | 31 | 4 | 0 | .000 | 0 | 0 | .000 | 13 | 3.3 | 20 | 8 | .400 | 33.1 | .579 |
| Jeremy Sowers* | NYM | sp | 25 | 14 | 0 | .000 | 0 | 2 | .143 | 68 | 4.9 | 9 | 4 | .444 | 80.4 | .626 |
| Jeremy Sowers* | STL | sp | 25 | 2 | 0 | .000 | 0 | 0 | .000 | 11 | 5.5 | 0 | 0 | .000 | 47.5 | .737 |
| Jeremy Sowers* |   | sp | 25 | 16 | 0 | .000 | 0 | 2 | .125 | 79 | 4.9 | 9 | 4 | .444 | 76.3 | .635 |
| Justin Speier | SFG | mr | 34 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 5 | 0 | .000 | 18.9 | .656 |
| Russ Springer | BAL | mr | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 5 | .625 | 21.2 | .627 |
| Huston Street | CWS | cl | 24 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 4 | .667 | 15.8 | .661 |
| Jeff Suppan | SFG | sp | 33 | 32 | 1 | .031 | 0 | 13 | .406 | 216 | 6.8 | 22 | 6 | .273 | 89.9 | .624 |
| Brian Tallet* | SFG | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 0 | .000 | 21.0 | .620 |
| Taylor Tankersley* | MIL | mr | 25 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 20 | 4 | .200 | 16.6 | .574 |
| Jack Taschner* | LAD | mr | 30 | 1 | 0 | .000 | 0 | 0 | .000 | 3 | 3.0 | 23 | 7 | .304 | 17.6 | .571 |
| Julian Tavarez | MIL | sp | 35 | 4 | 0 | .000 | 0 | 3 | .750 | 9 | 2.3 | 1 | 0 | .000 | 40.4 | .645 |
| Brad Thompson | LAD | mr | 26 | 1 | 1 | 1.000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 54.3 | .620 |
| Matt Thornton* | CHI | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 0 | 0 | .000 | 39.5 | .646 |
| Mike Timlin | DET | mr | 42 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 2 | .250 | 16.3 | .645 |
| Josh Towers | CIN | sp | 31 | 2 | 0 | .000 | 0 | 2 | 1.000 | 12 | 6.0 | 21 | 6 | .286 | 21.9 | .697 |
| Steve Trachsel | MIL | sp | 37 | 10 | 0 | .000 | 0 | 2 | .200 | 40 | 4.0 | 5 | 3 | .600 | 68.2 | .589 |
| Derrick Turnbow | NYA | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 5 | .556 | 22.1 | .571 |
| Jose Valverde | CWS | cl | 28 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 15 | 1 | .067 | 17.7 | .601 |
| Rick VandenHurk | HOU | sp | 23 | 3 | 0 | .000 | 0 | 1 | .333 | 14 | 4.7 | 37 | 14 | .378 | 25.8 | .592 |
| Claudio Vargas | BAL | sp | 30 | 20 | 0 | .000 | 0 | 10 | .500 | 91 | 4.6 | 11 | 4 | .364 | 97.7 | .601 |
| Javier Vazquez | CWS | sp | 31 | 31 | 3 | .097 | 1 | 22 | .710 | 133 | 4.3 | 14 | 4 | .286 | 100.8 | .650 |
| Justin Verlander | STL | sp | 25 | 33 | 1 | .030 | 0 | 16 | .485 | 212 | 6.4 | 16 | 5 | .313 | 101.2 | .627 |
| Carlos Villanueva | STL | mr | 24 | 5 | 1 | .200 | 0 | 3 | .600 | 31 | 6.2 | 11 | 5 | .455 | 33.0 | .594 |
| Oscar Villarreal | PIT | mr | 26 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 17 | 6 | .353 | 21.4 | .626 |
| Ron Villone* | KCA | mr | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 14 | 5 | .357 | 20.1 | .608 |
| Luis Vizcaino | MIN | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 23 | 5 | .217 | 17.7 | .592 |
| Billy Wagner* | NYA | cl | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 4 | .148 | 16.4 | .657 |
| Adam Wainwright | PIT | sp | 26 | 32 | 1 | .031 | 0 | 16 | .500 | 188 | 5.9 | 29 | 18 | .621 | 96.5 | .627 |
| Tim Wakefield | CLE | sp | 41 | 16 | 0 | .000 | 0 | 9 | .563 | 69 | 4.3 | 17 | 3 | .176 | 94.1 | .617 |
| Tim Wakefield | MIN | sp | 41 | 13 | 0 | .000 | 0 | 6 | .462 | 68 | 5.2 | 5 | 0 | .000 | 94.8 | .628 |
| Tim Wakefield |   | sp | 41 | 29 | 0 | .000 | 0 | 15 | .517 | 137 | 4.7 | 22 | 3 | .136 | 94.4 | .622 |
| Jamie Walker* | BOS | mr | 36 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 22 | 4 | .182 | 16.2 | .641 |
| Chien-Ming Wang | CLE | sp | 28 | 29 | 1 | .034 | 1 | 23 | .793 | 115 | 4.0 | 17 | 5 | .294 | 98.3 | .627 |
| Jarrod Washburn* | BOS | sp | 33 | 29 | 1 | .034 | 0 | 11 | .379 | 164 | 5.7 | 13 | 1 | .077 | 100.8 | .631 |
| David Weathers | CIN | cl | 38 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 12 | 1 | .083 | 15.9 | .610 |
| Jered Weaver | PHI | sp | 25 | 26 | 1 | .038 | 0 | 15 | .577 | 144 | 5.5 | 8 | 4 | .500 | 94.5 | .641 |
| Brandon Webb | SFG | sp | 29 | 18 | 1 | .056 | 0 | 11 | .611 | 110 | 6.1 | 8 | 2 | .250 | 102.4 | .644 |
| Brandon Webb | WAS | sp | 29 | 14 | 3 | .214 | 0 | 5 | .357 | 51 | 3.6 | 9 | 6 | .667 | 107.8 | .620 |
| Brandon Webb |   | sp | 29 | 32 | 4 | .125 | 0 | 16 | .500 | 161 | 5.0 | 17 | 8 | .471 | 104.8 | .633 |
| Todd Wellemeyer | BOS | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 16 | 6 | .375 | 26.0 | .590 |
| Kip Wells | HOU | sp | 31 | 13 | 1 | .077 | 0 | 4 | .308 | 64 | 4.9 | 17 | 4 | .235 | 72.7 | .596 |
| Jake Westbrook | MIN | sp | 30 | 22 | 0 | .000 | 0 | 10 | .455 | 126 | 5.7 | 7 | 4 | .571 | 75.6 | .619 |
| Dan Wheeler | CIN | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 26 | 7 | .269 | 18.3 | .646 |
| Bob Wickman | SFG | cl | 39 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 3 | .333 | 24.0 | .610 |
| Woody Williams | BOS | sp | 41 | 5 | 0 | .000 | 0 | 2 | .400 | 22 | 4.4 | 6 | 2 | .333 | 59.3 | .602 |
| Dontrelle Willis* | CLE | sp | 26 | 34 | 0 | .000 | 0 | 15 | .441 | 136 | 4.0 | 26 | 11 | .423 | 92.9 | .604 |
| C.J. Wilson* | CIN | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 21 | 4 | .190 | 17.8 | .579 |
| Matt Wise | MIL | mr | 32 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 8 | 4 | .500 | 20.2 | .609 |
| Randy Wolf* | HOU | sp | 31 | 9 | 0 | .000 | 0 | 3 | .333 | 43 | 4.8 | 22 | 10 | .455 | 39.2 | .631 |
| Brian Wolfe | DET | mr | 27 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 11 | 0 | .000 | 12.5 | .643 |
| Kerry Wood | BOS | mr | 31 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 6 | 2 | .333 | 16.9 | .528 |
| Jamey Wright | MIL | mr | 33 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 18 | 7 | .389 | 23.7 | .579 |
| Michael Wuertz | LAD | mr | 29 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 27 | 8 | .296 | 19.0 | .614 |
| Tyler Yates | NYM | mr | 30 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 13 | 6 | .462 | 21.0 | .583 |
| Chris Young | CWS | sp | 29 | 28 | 0 | .000 | 0 | 18 | .643 | 104 | 3.7 | 8 | 1 | .125 | 96.7 | .581 |
| Carlos Zambrano | CAL | sp | 27 | 31 | 2 | .065 | 0 | 17 | .548 | 123 | 4.0 | 26 | 11 | .423 | 112.2 | .586 |
| Barry Zito* | PIT | sp | 30 | 32 | 3 | .094 | 2 | 16 | .500 | 204 | 6.4 | 24 | 10 | .417 | 95.3 | .623 |
| Joel Zumaya | DET | mr | 23 | 0 | 0 | .000 | 0 | 0 | .000 | 0 | 0.0 | 9 | 2 | .222 | 18.5 | .596 |
| Relief |
| Name | Team | P | Age | SVO | S | SV% | BS | BS% | HLD | IR | IRS | IR% | G | GR | GF | PCH/G | STR% |
| Jeremy Accardo | CHI | cl | 26 | 4 | 0 | .000 | 2 | .500 | 10 | 44 | 11 | .250 | 48 | 48 | 12 | 20.0 | .617 |
| Jeremy Affeldt* | CWS | mr | 29 | 0 | 0 | .000 | 0 | .000 | 9 | 22 | 6 | .273 | 42 | 42 | 7 | 20.6 | .561 |
| Bronson Arroyo | SFG | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 95.7 | .640 |
| Luis Ayala | CWS | mr | 30 | 3 | 1 | .333 | 1 | .333 | 2 | 6 | 1 | .167 | 15 | 15 | 7 | 20.5 | .586 |
| Cha Seung Baek | NYM | sp | 28 | 3 | 0 | .000 | 3 | 1.000 | 1 | 11 | 6 | .545 | 24 | 14 | 3 | 46.5 | .650 |
| Homer Bailey | HOU | sp | 22 | 7 | 4 | .571 | 3 | .429 | 2 | 17 | 8 | .471 | 35 | 35 | 11 | 20.2 | .541 |
| Scott Baker | MIL | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 10 | 2 | .200 | 30 | 14 | 9 | 60.0 | .661 |
| John Bale* | SFG | mr | 34 | 2 | 0 | .000 | 2 | 1.000 | 0 | 12 | 5 | .417 | 16 | 16 | 8 | 25.3 | .676 |
| Brian Bannister | HOU | sp | 27 | 3 | 1 | .333 | 2 | .667 | 2 | 11 | 5 | .455 | 41 | 21 | 8 | 56.0 | .631 |
| Miguel Batista | PIT | sp | 37 | 3 | 2 | .667 | 1 | .333 | 0 | 11 | 1 | .091 | 29 | 23 | 9 | 44.4 | .608 |
| Josh Beckett | WAS | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 31 | 1 | 1 | 97.3 | .653 |
| Erik Bedard* | HOU | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 1 | 0 | 102.5 | .639 |
| Erik Bedard* | STL | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 94.1 | .637 |
| Erik Bedard* |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 1 | 0 | 98.4 | .638 |
| Joe Beimel* | MIN | mr | 31 | 9 | 7 | .778 | 1 | .111 | 17 | 46 | 15 | .326 | 59 | 59 | 18 | 16.8 | .612 |
| Matt Belisle | SFG | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 0 | 0 | 90.1 | .659 |
| Heath Bell | KCA | mr | 30 | 10 | 8 | .800 | 1 | .100 | 16 | 22 | 6 | .273 | 65 | 65 | 24 | 19.4 | .630 |
| Joaquin Benoit | SFG | mr | 30 | 3 | 0 | .000 | 3 | 1.000 | 6 | 33 | 16 | .485 | 54 | 54 | 13 | 23.4 | .618 |
| Jason Bergmann | SFG | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 104.5 | .611 |
| Jason Bergmann | WAS | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 103.6 | .589 |
| Jason Bergmann |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 103.9 | .598 |
| Rafael Betancourt | BOS | mr | 33 | 7 | 6 | .857 | 1 | .143 | 3 | 15 | 6 | .400 | 27 | 27 | 18 | 18.0 | .695 |
| Rafael Betancourt | MIN | mr | 33 | 4 | 2 | .500 | 2 | .500 | 9 | 17 | 3 | .176 | 32 | 32 | 7 | 16.7 | .708 |
| Rafael Betancourt |   | mr | 33 | 11 | 8 | .727 | 3 | .273 | 12 | 32 | 9 | .281 | 59 | 59 | 25 | 17.3 | .702 |
| Chad Billingsley | CLE | mr | 23 | 4 | 2 | .500 | 1 | .250 | 11 | 49 | 15 | .306 | 67 | 58 | 15 | 33.8 | .589 |
| Joe Blanton | DET | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 90.8 | .652 |
| Jeremy Bonderman | DET | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 88.3 | .651 |
| Boof Bonser | CIN | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 33 | 1 | 0 | 84.3 | .642 |
| Dave Borkowski | BOS | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 4 | 1 | .250 | 5 | 5 | 0 | 23.4 | .632 |
| Joe Borowski | BAL | cl | 37 | 4 | 1 | .250 | 3 | .750 | 4 | 14 | 3 | .214 | 42 | 42 | 24 | 19.3 | .670 |
| Micah Bowie* | CWS | mr | 33 | 1 | 0 | .000 | 1 | 1.000 | 2 | 5 | 2 | .400 | 9 | 4 | 0 | 60.0 | .633 |
| Dallas Braden* | WAS | sp | 24 | 4 | 1 | .250 | 2 | .500 | 4 | 16 | 8 | .500 | 41 | 38 | 19 | 27.9 | .609 |
| Chad Bradford | BAL | mr | 33 | 7 | 1 | .143 | 6 | .857 | 6 | 31 | 14 | .452 | 41 | 41 | 10 | 17.3 | .648 |
| Doug Brocail | PIT | mr | 41 | 2 | 1 | .500 | 0 | .000 | 8 | 42 | 17 | .405 | 53 | 53 | 11 | 19.8 | .644 |
| Andrew Brown | LAD | mr | 27 | 5 | 5 | 1.000 | 0 | .000 | 4 | 18 | 1 | .056 | 29 | 28 | 11 | 23.2 | .619 |
| Jonathan Broxton | KCA | mr | 24 | 4 | 1 | .250 | 3 | .750 | 8 | 25 | 10 | .400 | 47 | 47 | 19 | 22.1 | .646 |
| Brian Bruney | WAS | mr | 26 | 5 | 2 | .400 | 3 | .600 | 3 | 11 | 3 | .273 | 27 | 27 | 15 | 26.8 | .536 |
| Taylor Buchholz | BAL | mr | 26 | 3 | 1 | .333 | 2 | .667 | 1 | 19 | 3 | .158 | 41 | 41 | 9 | 27.5 | .661 |
| Mark Buehrle* | CIN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 15 | 2 | 1 | 84.5 | .646 |
| Mark Buehrle* | CLE | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 97.8 | .654 |
| Mark Buehrle* |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 31 | 2 | 1 | 91.3 | .650 |
| Ambiorix Burgos | MIL | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 11 | 1 | .091 | 22 | 22 | 4 | 19.6 | .599 |
| A.J. Burnett | MIL | sp | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 13 | 2 | 2 | 100.9 | .633 |
| A.J. Burnett | NYA | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 1 | 1 | 92.7 | .612 |
| A.J. Burnett |   | sp | 31 | 1 | 0 | .000 | 1 | 1.000 | 0 | 0 | 0 | .000 | 26 | 3 | 3 | 96.8 | .623 |
| Brian Burres* | WAS | mr | 27 | 2 | 0 | .000 | 2 | 1.000 | 0 | 7 | 6 | .857 | 14 | 14 | 8 | 36.9 | .590 |
| Jared Burton | NYA | mr | 27 | 7 | 2 | .286 | 3 | .429 | 7 | 25 | 10 | .400 | 42 | 42 | 7 | 15.5 | .585 |
| Dave Bush | CIN | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 87.1 | .635 |
| Paul Byrd | NYM | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 15 | 1 | 0 | 83.0 | .685 |
| Tim Byrdak* | PIT | mr | 34 | 7 | 4 | .571 | 1 | .143 | 5 | 31 | 9 | .290 | 45 | 45 | 22 | 17.3 | .602 |
| Daniel Cabrera | WAS | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 30 | 1 | 0 | 118.7 | .587 |
| Matt Cain | LAD | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 106.8 | .595 |
| Matt Cain | CAL | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 107.4 | .593 |
| Matt Cain |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 107.1 | .595 |
| Kevin Cameron | CAL | mr | 28 | 0 | 0 | .000 | 0 | .000 | 1 | 23 | 8 | .348 | 37 | 37 | 18 | 25.8 | .545 |
| Matt Capps | CWS | mr | 24 | 10 | 9 | .900 | 1 | .100 | 9 | 36 | 14 | .389 | 63 | 63 | 27 | 15.4 | .690 |
| Chris Capuano* | BAL | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 1 | 0 | 87.1 | .595 |
| Fausto Carmona | PIT | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 96.4 | .647 |
| Chris Carpenter | MIN | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 71.0 | .549 |
| Santiago Casilla | STL | mr | 27 | 4 | 0 | .000 | 4 | 1.000 | 16 | 22 | 8 | .364 | 44 | 44 | 14 | 17.1 | .620 |
| Gustavo Chacin* | CHI | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 0 | 0 | 72.7 | .624 |
| Shawn Chacon | NYM | mr | 30 | 6 | 5 | .833 | 1 | .167 | 3 | 45 | 19 | .422 | 62 | 62 | 17 | 24.9 | .598 |
| Matt Chico* | BOS | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 104.0 | .571 |
| Vinnie Chulk | DET | mr | 29 | 3 | 0 | .000 | 1 | .333 | 7 | 13 | 4 | .308 | 31 | 31 | 10 | 19.3 | .652 |
| Roger Clemens | NYA | sp | 45 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 90.7 | .640 |
| Jesus Colome | CLE | mr | 30 | 6 | 3 | .500 | 2 | .333 | 21 | 42 | 17 | .405 | 62 | 62 | 21 | 16.1 | .589 |
| Jose Contreras | MIL | sp | 36 | 2 | 1 | .500 | 1 | .500 | 0 | 6 | 1 | .167 | 28 | 23 | 11 | 38.1 | .660 |
| Jose Contreras | CIN | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 85.3 | .616 |
| Jose Contreras |   | sp | 36 | 2 | 1 | .500 | 1 | .500 | 0 | 6 | 1 | .167 | 46 | 23 | 11 | 56.6 | .634 |
| Aaron Cook | MIN | sp | 29 | 3 | 1 | .333 | 1 | .333 | 0 | 11 | 4 | .364 | 34 | 13 | 5 | 65.6 | .638 |
| Chad Cordero | CLE | cl | 26 | 21 | 17 | .810 | 3 | .143 | 6 | 27 | 12 | .444 | 42 | 42 | 30 | 14.3 | .605 |
| Chad Cordero | DET | cl | 26 | 5 | 1 | .200 | 3 | .600 | 8 | 11 | 7 | .636 | 27 | 27 | 8 | 17.1 | .587 |
| Chad Cordero |   | cl | 26 | 26 | 18 | .692 | 6 | .231 | 14 | 38 | 19 | .500 | 69 | 69 | 38 | 15.4 | .597 |
| Francisco Cordero | NYA | cl | 33 | 5 | 2 | .400 | 3 | .600 | 15 | 47 | 15 | .319 | 64 | 64 | 12 | 14.5 | .617 |
| Manny Corpas | PIT | mr | 25 | 7 | 4 | .571 | 3 | .429 | 8 | 21 | 7 | .333 | 36 | 36 | 12 | 19.3 | .636 |
| Kevin Correia | LAD | mr | 27 | 1 | 0 | .000 | 1 | 1.000 | 1 | 9 | 2 | .222 | 23 | 8 | 2 | 72.3 | .615 |
| Neal Cotts* | CLE | mr | 28 | 1 | 0 | .000 | 0 | .000 | 5 | 11 | 3 | .273 | 21 | 21 | 5 | 13.9 | .581 |
| Juan Cruz | NYM | mr | 29 | 4 | 2 | .500 | 2 | .500 | 7 | 31 | 7 | .226 | 44 | 44 | 14 | 24.8 | .592 |
| John Danks* | BOS | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 21 | 2 | 2 | 79.2 | .633 |
| Kyle Davies | WAS | sp | 24 | 1 | 0 | .000 | 1 | 1.000 | 1 | 2 | 2 | 1.000 | 25 | 7 | 4 | 92.9 | .571 |
| Doug Davis* | MIL | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 35 | 7 | 6 | 80.8 | .593 |
| Jorge De La Rosa* | NYM | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 108.0 | .694 |
| Manny Delcarmen | KCA | mr | 26 | 3 | 1 | .333 | 2 | .667 | 8 | 32 | 15 | .469 | 32 | 32 | 9 | 20.8 | .579 |
| Ryan Dempster | BAL | cl | 31 | 12 | 9 | .750 | 3 | .250 | 6 | 21 | 8 | .381 | 49 | 49 | 28 | 19.1 | .596 |
| Lenny DiNardo* | NYM | sp | 28 | 4 | 2 | .500 | 1 | .250 | 1 | 27 | 12 | .444 | 49 | 37 | 16 | 40.6 | .623 |
| Brendan Donnelly | BOS | mr | 36 | 0 | 0 | .000 | 0 | .000 | 3 | 11 | 5 | .455 | 14 | 14 | 3 | 19.6 | .602 |
| Scott Downs* | NYM | mr | 32 | 15 | 11 | .733 | 4 | .267 | 2 | 19 | 7 | .368 | 45 | 45 | 35 | 19.0 | .612 |
| Brandon Duckworth | CLE | mr | 32 | 2 | 1 | .500 | 0 | .000 | 1 | 6 | 1 | .167 | 12 | 12 | 7 | 13.8 | .552 |
| Zach Duke* | CHI | sp | 25 | 0 | 0 | .000 | 0 | .000 | 5 | 23 | 5 | .217 | 50 | 50 | 23 | 24.4 | .638 |
| Chad Durbin | NYM | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 3 | .600 | 29 | 10 | 6 | 67.1 | .627 |
| J.D. Durbin | WAS | sp | 26 | 5 | 1 | .200 | 4 | .800 | 6 | 26 | 8 | .308 | 38 | 36 | 16 | 27.3 | .588 |
| Alan Embree* | BOS | cl | 38 | 10 | 3 | .300 | 6 | .600 | 6 | 36 | 17 | .472 | 43 | 43 | 12 | 14.0 | .660 |
| Alan Embree* | MIN | cl | 38 | 2 | 0 | .000 | 1 | .500 | 4 | 14 | 5 | .357 | 23 | 23 | 5 | 16.3 | .662 |
| Alan Embree* |   | cl | 38 | 12 | 3 | .250 | 7 | .583 | 10 | 50 | 22 | .440 | 66 | 66 | 17 | 14.8 | .661 |
| Kelvim Escobar | NYA | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 1 | 0 | 94.9 | .616 |
| Kyle Farnsworth | CLE | mr | 32 | 7 | 5 | .714 | 2 | .286 | 6 | 47 | 13 | .277 | 52 | 52 | 15 | 17.3 | .616 |
| Pedro Feliciano* | STL | mr | 31 | 4 | 2 | .500 | 0 | .000 | 16 | 19 | 8 | .421 | 61 | 61 | 19 | 16.2 | .570 |
| Josh Fogg | SFG | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 11 | 0 | 0 | 88.1 | .609 |
| Jeff Francis* | DET | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 96.0 | .623 |
| Frank Francisco | PHI | mr | 28 | 3 | 0 | .000 | 2 | .667 | 9 | 17 | 3 | .176 | 37 | 37 | 8 | 21.0 | .584 |
| Ryan Franklin | CWS | mr | 35 | 4 | 2 | .500 | 2 | .500 | 6 | 37 | 16 | .432 | 50 | 50 | 10 | 21.4 | .649 |
| Jason Frasor | SFG | mr | 30 | 0 | 0 | .000 | 0 | .000 | 2 | 21 | 8 | .381 | 33 | 33 | 10 | 24.3 | .613 |
| Brian Fuentes* | LAD | cl | 32 | 6 | 4 | .667 | 2 | .333 | 2 | 11 | 5 | .455 | 15 | 15 | 5 | 18.1 | .542 |
| Brian Fuentes* | NYA | cl | 32 | 4 | 0 | .000 | 3 | .750 | 13 | 35 | 14 | .400 | 57 | 57 | 12 | 12.7 | .554 |
| Brian Fuentes* |   | cl | 32 | 10 | 4 | .400 | 5 | .500 | 15 | 46 | 19 | .413 | 72 | 72 | 17 | 13.8 | .551 |
| Aaron Fultz* | CAL | mr | 34 | 4 | 0 | .000 | 1 | .250 | 11 | 32 | 6 | .188 | 43 | 43 | 9 | 13.2 | .583 |
| Kason Gabbard* | CAL | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 103.0 | .595 |
| Eric Gagne | MIL | cl | 32 | 12 | 6 | .500 | 6 | .500 | 0 | 17 | 5 | .294 | 25 | 25 | 17 | 21.8 | .555 |
| Eric Gagne | BOS | cl | 32 | 1 | 0 | .000 | 1 | 1.000 | 1 | 5 | 1 | .200 | 13 | 13 | 5 | 23.2 | .551 |
| Eric Gagne |   | cl | 32 | 13 | 6 | .462 | 7 | .538 | 1 | 22 | 6 | .273 | 38 | 38 | 22 | 22.2 | .554 |
| Yovani Gallardo | MIL | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 99.6 | .616 |
| Yovani Gallardo | PIT | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 107.3 | .601 |
| Yovani Gallardo |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 101.9 | .611 |
| Lee Gardner | PIT | mr | 33 | 7 | 4 | .571 | 1 | .143 | 9 | 43 | 12 | .279 | 61 | 61 | 21 | 18.0 | .647 |
| Jon Garland | KCA | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 97.6 | .653 |
| Matt Garza | CAL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 107.3 | .632 |
| Chad Gaudin | CIN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 1 | 0 | 82.6 | .604 |
| Chad Gaudin | STL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 2 | 0 | 89.3 | .599 |
| Chad Gaudin |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 3 | 0 | 85.9 | .602 |
| Geoff Geary | BOS | mr | 31 | 3 | 2 | .667 | 1 | .333 | 3 | 12 | 3 | .250 | 21 | 21 | 7 | 18.0 | .648 |
| Justin Germano | CAL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 103.2 | .642 |
| Tom Glavine* | LAD | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 90.9 | .624 |
| Jimmy Gobble* | PHI | mr | 26 | 1 | 0 | .000 | 0 | .000 | 7 | 33 | 8 | .242 | 38 | 38 | 16 | 11.5 | .604 |
| Edgar Gonzalez | CWS | mr | 25 | 2 | 1 | .500 | 1 | .500 | 0 | 2 | 1 | .500 | 9 | 7 | 4 | 42.2 | .611 |
| Tom Gorzelanny* | PIT | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 94.7 | .612 |
| John Grabow* | NYM | mr | 29 | 4 | 2 | .500 | 2 | .500 | 1 | 5 | 1 | .200 | 10 | 10 | 2 | 20.4 | .642 |
| Sean Green | MIL | mr | 29 | 3 | 0 | .000 | 3 | 1.000 | 6 | 15 | 6 | .400 | 33 | 33 | 6 | 22.5 | .565 |
| Kevin Gregg | CAL | cl | 30 | 29 | 26 | .897 | 3 | .103 | 1 | 16 | 7 | .438 | 48 | 48 | 45 | 22.8 | .554 |
| Zack Greinke | CHI | mr | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 92.4 | .665 |
| Jason Grilli | SFG | mr | 31 | 4 | 2 | .500 | 2 | .500 | 4 | 26 | 10 | .385 | 30 | 30 | 4 | 23.7 | .606 |
| Matt Guerrier | PHI | mr | 29 | 8 | 4 | .500 | 3 | .375 | 19 | 53 | 10 | .189 | 69 | 69 | 16 | 16.7 | .648 |
| Jeremy Guthrie | CHI | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 27 | 0 | 0 | 90.6 | .646 |
| Roy Halladay | NYA | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 95.4 | .661 |
| Cole Hamels* | MIN | sp | 24 | 1 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 30 | 1 | 0 | 95.2 | .648 |
| Jason Hammel | NYM | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 97.0 | .598 |
| Justin Hampson* | CWS | mr | 28 | 3 | 1 | .333 | 1 | .333 | 8 | 17 | 4 | .235 | 43 | 43 | 14 | 16.9 | .618 |
| Joel Hanrahan | PHI | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 88.2 | .548 |
| Aaron Harang | STL | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 104.1 | .660 |
| Rich Harden | WAS | sp | 26 | 3 | 2 | .667 | 1 | .333 | 2 | 5 | 0 | .000 | 14 | 14 | 8 | 23.4 | .578 |
| Dan Haren | LAD | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 101.1 | .668 |
| Dan Haren | CAL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 108.0 | .630 |
| Dan Haren |   | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 104.2 | .650 |
| LaTroy Hawkins | SFG | mr | 35 | 5 | 2 | .400 | 2 | .400 | 4 | 25 | 6 | .240 | 33 | 33 | 12 | 20.5 | .615 |
| Aaron Heilman | LAD | mr | 29 | 10 | 5 | .500 | 5 | .500 | 19 | 52 | 15 | .288 | 68 | 68 | 13 | 17.3 | .622 |
| Mark Hendrickson* | WAS | mr | 34 | 2 | 2 | 1.000 | 0 | .000 | 7 | 17 | 7 | .412 | 61 | 59 | 22 | 30.4 | .619 |
| Brad Hennessey | PHI | cl | 28 | 3 | 0 | .000 | 3 | 1.000 | 11 | 40 | 16 | .400 | 52 | 52 | 13 | 19.8 | .603 |
| Matt Herges | NYA | mr | 38 | 4 | 3 | .750 | 0 | .000 | 10 | 38 | 10 | .263 | 43 | 43 | 10 | 15.0 | .596 |
| Felix Hernandez | DET | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 97.4 | .640 |
| Livan Hernandez | BOS | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 89.4 | .594 |
| Orlando Hernandez | NYM | sp | 38 | 1 | 1 | 1.000 | 0 | .000 | 0 | 2 | 1 | .500 | 25 | 2 | 2 | 95.0 | .602 |
| Rich Hill* | BAL | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 93.6 | .620 |
| Shawn Hill | LAD | sp | 27 | 1 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 15 | 1 | 0 | 91.6 | .624 |
| Jason Hirsh | CHI | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 3 | 2 | 78.0 | .619 |
| Trevor Hoffman | BAL | cl | 40 | 11 | 8 | .727 | 2 | .182 | 0 | 15 | 2 | .133 | 38 | 38 | 30 | 17.8 | .645 |
| J.P. Howell* | CIN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 5 | 1 | .200 | 14 | 5 | 2 | 64.0 | .631 |
| Bob Howry | CIN | mr | 34 | 2 | 1 | .500 | 0 | .000 | 3 | 52 | 15 | .288 | 61 | 61 | 12 | 19.4 | .651 |
| Tim Hudson | PHI | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 105.5 | .651 |
| Tim Hudson | KCA | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 93.7 | .646 |
| Tim Hudson |   | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 98.6 | .648 |
| Phil Hughes | CIN | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 88.5 | .641 |
| Phil Hughes | CLE | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 8 | 0 | 0 | 93.9 | .602 |
| Phil Hughes |   | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 92.1 | .614 |
| Jason Isringhausen | STL | cl | 35 | 42 | 36 | .857 | 6 | .143 | 3 | 30 | 2 | .067 | 61 | 61 | 53 | 15.7 | .605 |
| Edwin Jackson | MIL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 1 | 8 | 2 | .250 | 35 | 12 | 5 | 67.9 | .596 |
| Chuck James* | KCA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 17 | 1 | 0 | 90.4 | .624 |
| Casey Janssen | HOU | mr | 26 | 17 | 14 | .824 | 3 | .176 | 1 | 24 | 11 | .458 | 33 | 33 | 23 | 18.1 | .655 |
| Casey Janssen | STL | mr | 26 | 2 | 2 | 1.000 | 0 | .000 | 5 | 5 | 1 | .200 | 23 | 23 | 11 | 18.7 | .643 |
| Casey Janssen |   | mr | 26 | 19 | 16 | .842 | 3 | .158 | 6 | 29 | 12 | .414 | 56 | 56 | 34 | 18.3 | .650 |
| Bobby Jenks | DET | cl | 27 | 31 | 29 | .935 | 2 | .065 | 2 | 34 | 12 | .353 | 57 | 57 | 50 | 15.3 | .649 |
| Jason Jennings | PIT | sp | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 3 | 1.000 | 2 | 2 | 0 | 31.0 | .581 |
| Ubaldo Jimenez | LAD | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 5 | 2 | 1 | 63.2 | .601 |
| Ubaldo Jimenez | CAL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 9 | 0 | 0 | 115.0 | .596 |
| Ubaldo Jimenez |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 14 | 2 | 1 | 96.5 | .597 |
| Josh Johnson | MIL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 61.2 | .618 |
| Randy Johnson* | KCA | sp | 44 | 1 | 0 | .000 | 0 | .000 | 0 | 7 | 3 | .429 | 17 | 11 | 4 | 42.4 | .656 |
| Tyler Johnson* | STL | mr | 27 | 6 | 1 | .167 | 2 | .333 | 13 | 25 | 5 | .200 | 45 | 45 | 11 | 12.0 | .650 |
| Todd Jones | CIN | cl | 40 | 2 | 1 | .500 | 1 | .500 | 3 | 22 | 4 | .182 | 39 | 39 | 13 | 17.4 | .616 |
| Jorge Julio | BAL | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 5 | 18 | 10 | .556 | 39 | 39 | 11 | 20.7 | .568 |
| Scott Kazmir* | CIN | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 92.6 | .592 |
| Scott Kazmir* | CLE | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 110.3 | .614 |
| Scott Kazmir* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 101.2 | .604 |
| Kyle Kendrick | MIL | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 15 | 0 | 0 | 90.0 | .664 |
| Joe Kennedy* | LAD | mr | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 1 | 1 | 67.0 | .642 |
| Logan Kensing | PIT | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 0 | 4 | 2 | .500 | 6 | 6 | 3 | 25.3 | .664 |
| Ray King* | NYM | mr | 34 | 4 | 1 | .250 | 2 | .500 | 6 | 23 | 11 | .478 | 34 | 34 | 12 | 17.7 | .588 |
| John Lackey | KCA | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 97.0 | .649 |
| Aaron Laffey* | HOU | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 5 | .714 | 9 | 6 | 6 | 44.0 | .672 |
| Aaron Laffey* | STL | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 74.8 | .632 |
| Aaron Laffey* |   | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 0 | 7 | 5 | .714 | 13 | 6 | 6 | 53.5 | .655 |
| John Lannan* | SFG | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 1 | 0 | 0 | 93.0 | .591 |
| John Lannan* | WAS | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 3 | 3 | 68.7 | .546 |
| John Lannan* |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 7 | 3 | 3 | 72.1 | .554 |
| Brandon League | WAS | mr | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 6 | 2 | .333 | 9 | 9 | 5 | 15.9 | .622 |
| Cliff Lee* | PHI | sp | 29 | 3 | 1 | .333 | 1 | .333 | 11 | 50 | 16 | .320 | 67 | 67 | 12 | 23.7 | .612 |
| Jon Lester* | HOU | sp | 24 | 3 | 2 | .667 | 1 | .333 | 2 | 33 | 9 | .273 | 38 | 36 | 9 | 24.3 | .613 |
| Brad Lidge | PHI | cl | 31 | 47 | 42 | .894 | 5 | .106 | 1 | 20 | 7 | .350 | 60 | 60 | 50 | 15.4 | .621 |
| Jon Lieber | PHI | sp | 38 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 93.2 | .654 |
| Ted Lilly* | SFG | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 94.6 | .639 |
| Tim Lincecum | WAS | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 104.2 | .600 |
| Matt Lindstrom | CAL | mr | 28 | 2 | 1 | .500 | 1 | .500 | 8 | 31 | 8 | .258 | 45 | 45 | 22 | 21.5 | .635 |
| Scott Linebrink | CLE | mr | 31 | 8 | 4 | .500 | 3 | .375 | 11 | 43 | 21 | .488 | 62 | 62 | 22 | 17.4 | .614 |
| Jesse Litsch | LAD | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 81.5 | .644 |
| Jesse Litsch | CAL | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 91.6 | .626 |
| Jesse Litsch |   | sp | 23 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 89.4 | .630 |
| Wes Littleton | LAD | mr | 25 | 1 | 1 | 1.000 | 0 | .000 | 3 | 7 | 4 | .571 | 24 | 21 | 12 | 32.9 | .580 |
| Kameron Loe | NYM | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 103.5 | .580 |
| Adam Loewen* | NYM | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 6 | 0 | 0 | 108.0 | .522 |
| Boone Logan* | NYM | mr | 23 | 1 | 0 | .000 | 0 | .000 | 5 | 27 | 14 | .519 | 35 | 35 | 5 | 22.1 | .627 |
| Kyle Lohse | MIN | sp | 29 | 1 | 0 | .000 | 0 | .000 | 0 | 2 | 0 | .000 | 32 | 2 | 0 | 88.6 | .632 |
| Braden Looper | CAL | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 111.2 | .613 |
| Javier Lopez* | LAD | mr | 30 | 2 | 2 | 1.000 | 0 | .000 | 2 | 3 | 0 | .000 | 15 | 7 | 3 | 42.9 | .554 |
| Rodrigo Lopez | STL | sp | 32 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 88.7 | .648 |
| Derek Lowe | CWS | sp | 35 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 1 | 1 | 101.0 | .621 |
| Noah Lowry* | CAL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 118.4 | .573 |
| Brandon Lyon | MIN | mr | 28 | 22 | 16 | .727 | 5 | .227 | 6 | 43 | 10 | .233 | 60 | 60 | 38 | 18.1 | .603 |
| Greg Maddux | BAL | sp | 42 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 91.5 | .685 |
| Ryan Madson | CAL | mr | 27 | 4 | 3 | .750 | 1 | .250 | 3 | 25 | 10 | .400 | 36 | 36 | 20 | 23.9 | .590 |
| Ron Mahay* | CAL | mr | 37 | 7 | 2 | .286 | 5 | .714 | 4 | 44 | 18 | .409 | 47 | 47 | 16 | 20.2 | .579 |
| Paul Maholm* | PHI | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 32 | 2 | 1 | 81.4 | .620 |
| John Maine | PHI | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 32 | 1 | 0 | 95.3 | .618 |
| Shaun Marcum | CHI | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 25 | 0 | 0 | 93.7 | .644 |
| Carlos Marmol | CHI | mr | 25 | 14 | 8 | .571 | 5 | .357 | 21 | 41 | 8 | .195 | 64 | 64 | 18 | 17.9 | .573 |
| Jason Marquis | HOU | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 32 | 3 | 1 | 90.3 | .621 |
| Sean Marshall* | NYM | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 19 | 0 | 0 | 85.4 | .624 |
| Damaso Marte* | MIL | mr | 33 | 2 | 0 | .000 | 2 | 1.000 | 3 | 26 | 12 | .462 | 38 | 38 | 8 | 18.6 | .629 |
| Pedro Martinez | NYA | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 5 | 0 | 0 | 72.2 | .673 |
| Daisuke Matsuzaka | DET | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 98.0 | .616 |
| Brandon McCarthy | DET | sp | 24 | 3 | 0 | .000 | 1 | .333 | 4 | 6 | 3 | .500 | 31 | 23 | 5 | 46.3 | .559 |
| Dustin McGowan | NYA | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 99.6 | .630 |
| Gil Meche | CHI | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 96.9 | .647 |
| Cla Meredith | DET | mr | 25 | 4 | 1 | .250 | 0 | .000 | 9 | 40 | 11 | .275 | 62 | 62 | 15 | 15.7 | .652 |
| Andrew Miller* | HOU | sp | 23 | 9 | 2 | .222 | 6 | .667 | 4 | 34 | 9 | .265 | 49 | 49 | 22 | 23.3 | .583 |
| Justin Miller | HOU | mr | 30 | 10 | 7 | .700 | 3 | .300 | 2 | 47 | 16 | .340 | 47 | 47 | 19 | 21.0 | .624 |
| Trever Miller* | BOS | mr | 35 | 3 | 2 | .667 | 1 | .333 | 3 | 11 | 5 | .455 | 19 | 19 | 6 | 17.3 | .578 |
| Kevin Millwood | BAL | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 94.8 | .624 |
| Zach Miner | KCA | mr | 26 | 0 | 0 | .000 | 0 | .000 | 1 | 6 | 2 | .333 | 14 | 6 | 4 | 62.5 | .630 |
| Sergio Mitre | PHI | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 86.4 | .623 |
| Brian Moehler | NYM | mr | 36 | 1 | 1 | 1.000 | 0 | .000 | 2 | 8 | 3 | .375 | 12 | 12 | 5 | 28.8 | .652 |
| Franklin Morales* | BOS | sp | 22 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 5 | 1 | 0 | 89.0 | .604 |
| Matt Morris | NYM | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 35 | 3 | 2 | 84.9 | .623 |
| Brandon Morrow | NYM | mr | 23 | 8 | 5 | .625 | 3 | .375 | 5 | 24 | 8 | .333 | 45 | 45 | 15 | 23.8 | .550 |
| Dustin Moseley | NYA | mr | 26 | 1 | 1 | 1.000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 3 | 2 | 81.2 | .652 |
| Guillermo Mota | CLE | mr | 34 | 6 | 3 | .500 | 3 | .500 | 3 | 23 | 10 | .435 | 30 | 30 | 7 | 22.7 | .629 |
| Jamie Moyer* | BOS | sp | 45 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 1 | 0 | 85.9 | .605 |
| Peter Moylan | PIT | mr | 29 | 35 | 30 | .857 | 5 | .143 | 0 | 38 | 13 | .342 | 69 | 69 | 62 | 17.8 | .635 |
| Mike Mussina | CLE | sp | 39 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 1 | 1.000 | 27 | 2 | 1 | 82.9 | .668 |
| Brett Myers | LAD | cl | 27 | 1 | 0 | .000 | 1 | 1.000 | 0 | 4 | 3 | .750 | 14 | 3 | 2 | 81.8 | .595 |
| Joe Nathan | MIL | cl | 33 | 9 | 8 | .889 | 1 | .111 | 1 | 17 | 5 | .294 | 36 | 36 | 23 | 17.0 | .640 |
| Joe Nathan | MIN | cl | 33 | 12 | 10 | .833 | 2 | .167 | 1 | 17 | 8 | .471 | 23 | 23 | 16 | 19.5 | .624 |
| Joe Nathan |   | cl | 33 | 21 | 18 | .857 | 3 | .143 | 2 | 34 | 13 | .382 | 59 | 59 | 39 | 18.0 | .633 |
| Pat Neshek | CIN | mr | 27 | 4 | 2 | .500 | 2 | .500 | 7 | 13 | 8 | .615 | 33 | 33 | 11 | 20.5 | .645 |
| Pat Neshek | STL | mr | 27 | 4 | 2 | .500 | 1 | .250 | 5 | 11 | 3 | .273 | 25 | 25 | 5 | 16.6 | .655 |
| Pat Neshek |   | mr | 27 | 8 | 4 | .500 | 3 | .375 | 12 | 24 | 11 | .458 | 58 | 58 | 16 | 18.8 | .649 |
| Dustin Nippert | CWS | mr | 27 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 1 | .333 | 5 | 5 | 2 | 14.0 | .543 |
| Leo Nunez | CWS | mr | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 6 | 1 | .167 | 9 | 6 | 4 | 49.0 | .637 |
| Eric O'Flaherty* | PHI | mr | 23 | 1 | 0 | .000 | 0 | .000 | 15 | 31 | 12 | .387 | 46 | 46 | 14 | 14.8 | .624 |
| Hideki Okajima* | CHI | mr | 32 | 7 | 3 | .429 | 4 | .571 | 7 | 21 | 5 | .238 | 41 | 41 | 16 | 20.3 | .672 |
| Darren Oliver* | BAL | mr | 37 | 5 | 3 | .600 | 2 | .400 | 4 | 22 | 6 | .273 | 40 | 40 | 13 | 21.5 | .606 |
| Scott Olsen* | MIL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 18 | 4 | .222 | 23 | 18 | 5 | 42.0 | .609 |
| Scott Olsen* | WAS | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 0 | 0 | 102.4 | .570 |
| Scott Olsen* |   | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 18 | 4 | .222 | 40 | 18 | 5 | 67.7 | .584 |
| Garrett Olson* | WAS | sp | 24 | 1 | 0 | .000 | 0 | .000 | 2 | 2 | 0 | .000 | 12 | 7 | 0 | 50.1 | .546 |
| Ramon Ortiz | LAD | mr | 35 | 1 | 0 | .000 | 1 | 1.000 | 0 | 2 | 0 | .000 | 3 | 2 | 1 | 48.0 | .667 |
| Roy Oswalt | CWS | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 101.9 | .621 |
| Akinori Otsuka | NYA | mr | 36 | 1 | 0 | .000 | 1 | 1.000 | 1 | 9 | 6 | .667 | 22 | 22 | 7 | 17.4 | .601 |
| Micah Owings | MIN | sp | 25 | 3 | 3 | 1.000 | 0 | .000 | 1 | 8 | 0 | .000 | 31 | 8 | 4 | 76.4 | .602 |
| Vicente Padilla | BOS | sp | 30 | 1 | 1 | 1.000 | 0 | .000 | 0 | 5 | 1 | .200 | 15 | 3 | 3 | 71.9 | .597 |
| Vicente Padilla | MIN | sp | 30 | 2 | 2 | 1.000 | 0 | .000 | 1 | 10 | 2 | .200 | 21 | 18 | 7 | 30.4 | .641 |
| Vicente Padilla |   | sp | 30 | 3 | 3 | 1.000 | 0 | .000 | 1 | 15 | 3 | .200 | 36 | 21 | 10 | 47.7 | .613 |
| Jonathan Papelbon | NYA | cl | 27 | 40 | 32 | .800 | 7 | .175 | 0 | 11 | 4 | .364 | 55 | 55 | 44 | 16.1 | .627 |
| Chad Paronto | MIL | mr | 32 | 1 | 0 | .000 | 1 | 1.000 | 0 | 8 | 2 | .250 | 12 | 12 | 7 | 16.4 | .558 |
| John Patterson | CWS | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 4 | 0 | 0 | 91.3 | .559 |
| Jake Peavy | CHI | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 104.3 | .656 |
| Mike Pelfrey | MIL | sp | 24 | 1 | 1 | 1.000 | 0 | .000 | 0 | 25 | 7 | .280 | 37 | 36 | 13 | 25.7 | .557 |
| Tony Pena | STL | mr | 26 | 5 | 2 | .400 | 3 | .600 | 21 | 32 | 12 | .375 | 68 | 68 | 14 | 18.0 | .603 |
| Brad Penny | SFG | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 96.3 | .597 |
| Brad Penny | DET | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 91.8 | .608 |
| Brad Penny |   | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 30 | 0 | 0 | 94.5 | .601 |
| Joel Peralta | BAL | mr | 32 | 5 | 3 | .600 | 2 | .400 | 4 | 46 | 17 | .370 | 51 | 51 | 14 | 22.2 | .671 |
| Troy Percival | CHI | mr | 38 | 5 | 2 | .400 | 2 | .400 | 10 | 24 | 6 | .250 | 38 | 38 | 12 | 15.6 | .642 |
| Odalis Perez* | LAD | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 3 | 1 | 1 | 96.3 | .564 |
| Oliver Perez* | MIL | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 105.7 | .580 |
| Oliver Perez* | CLE | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 10 | 1 | 1 | 101.5 | .600 |
| Oliver Perez* |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 1 | 1 | 104.2 | .587 |
| Rafael Perez* | KCA | mr | 26 | 6 | 3 | .500 | 2 | .333 | 16 | 32 | 7 | .219 | 47 | 47 | 14 | 17.0 | .635 |
| Yusmeiro Petit | WAS | sp | 23 | 7 | 4 | .571 | 2 | .286 | 4 | 17 | 5 | .294 | 35 | 32 | 21 | 22.4 | .655 |
| Andy Pettitte* | PIT | sp | 36 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 97.6 | .637 |
| Joel Pineiro | MIN | mr | 29 | 0 | 0 | .000 | 0 | .000 | 5 | 14 | 6 | .429 | 37 | 30 | 10 | 33.5 | .621 |
| Renyel Pinto* | DET | mr | 25 | 6 | 2 | .333 | 0 | .000 | 12 | 41 | 5 | .122 | 58 | 58 | 13 | 13.8 | .567 |
| Scott Proctor | LAD | mr | 31 | 10 | 4 | .400 | 4 | .400 | 4 | 47 | 22 | .468 | 65 | 65 | 27 | 22.8 | .592 |
| J.J. Putz | CHI | cl | 31 | 40 | 35 | .875 | 5 | .125 | 0 | 28 | 4 | .143 | 60 | 60 | 51 | 15.5 | .638 |
| Chad Qualls | MIN | mr | 29 | 8 | 5 | .625 | 2 | .250 | 12 | 29 | 5 | .172 | 52 | 52 | 17 | 22.2 | .633 |
| Jon Rauch | LAD | mr | 29 | 22 | 15 | .682 | 6 | .273 | 5 | 30 | 8 | .267 | 60 | 60 | 31 | 18.9 | .626 |
| Jon Rauch | NYA | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 5 | 3 | 1 | .333 | 12 | 12 | 3 | 18.2 | .683 |
| Jon Rauch |   | mr | 29 | 23 | 15 | .652 | 7 | .304 | 10 | 33 | 9 | .273 | 72 | 72 | 34 | 18.7 | .635 |
| Chris Ray | DET | cl | 26 | 4 | 3 | .750 | 1 | .250 | 5 | 10 | 2 | .200 | 26 | 26 | 9 | 23.4 | .599 |
| Tim Redding | STL | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 92.6 | .593 |
| Al Reyes | CIN | cl | 38 | 11 | 5 | .455 | 5 | .455 | 10 | 27 | 8 | .296 | 48 | 48 | 18 | 19.8 | .624 |
| Anthony Reyes | MIN | sp | 26 | 2 | 1 | .500 | 1 | .500 | 2 | 7 | 2 | .286 | 26 | 26 | 11 | 24.7 | .621 |
| Jo-Jo Reyes* | WAS | sp | 23 | 1 | 1 | 1.000 | 0 | .000 | 1 | 3 | 0 | .000 | 16 | 12 | 6 | 56.0 | .547 |
| John Rheinecker* | NYM | mr | 29 | 1 | 0 | .000 | 1 | 1.000 | 0 | 3 | 2 | .667 | 17 | 8 | 2 | 53.0 | .599 |
| Juan Rincon | STL | mr | 29 | 2 | 2 | 1.000 | 0 | .000 | 8 | 17 | 5 | .294 | 37 | 37 | 10 | 17.2 | .627 |
| David Riske | CAL | mr | 31 | 5 | 1 | .200 | 3 | .600 | 13 | 37 | 9 | .243 | 52 | 52 | 17 | 18.0 | .616 |
| Mariano Rivera | NYA | cl | 38 | 4 | 1 | .250 | 3 | .750 | 6 | 36 | 12 | .333 | 55 | 55 | 19 | 16.1 | .673 |
| Saul Rivera | CWS | mr | 30 | 4 | 2 | .500 | 2 | .500 | 2 | 2 | 0 | .000 | 19 | 19 | 8 | 23.4 | .607 |
| Nate Robertson* | HOU | sp | 30 | 0 | 0 | .000 | 0 | .000 | 1 | 2 | 1 | .500 | 32 | 3 | 1 | 87.5 | .630 |
| Fernando Rodney | CHI | mr | 31 | 5 | 4 | .800 | 0 | .000 | 14 | 32 | 11 | .344 | 47 | 47 | 7 | 14.7 | .625 |
| Francisco Rodriguez | SFG | cl | 26 | 12 | 7 | .583 | 4 | .333 | 3 | 24 | 4 | .167 | 53 | 53 | 21 | 19.8 | .613 |
| Wandy Rodriguez* | LAD | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 28 | 0 | 0 | 102.5 | .629 |
| Kenny Rogers* | CHI | sp | 43 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 10 | 2 | 0 | 81.9 | .621 |
| J.C. Romero* | CLE | mr | 32 | 16 | 8 | .500 | 6 | .375 | 19 | 57 | 8 | .140 | 68 | 68 | 19 | 13.3 | .550 |
| Ryan Rowland-Smith* | WAS | mr | 25 | 12 | 7 | .583 | 5 | .417 | 2 | 11 | 3 | .273 | 28 | 28 | 21 | 21.3 | .595 |
| C.C. Sabathia* | NYA | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 102.8 | .686 |
| Takashi Saito | SFG | cl | 38 | 18 | 16 | .889 | 2 | .111 | 2 | 21 | 4 | .190 | 43 | 43 | 37 | 18.7 | .662 |
| Juan Salas | NYM | mr | 29 | 1 | 1 | 1.000 | 0 | .000 | 2 | 8 | 1 | .125 | 23 | 23 | 9 | 18.9 | .620 |
| Chris Sampson | BOS | sp | 30 | 7 | 4 | .571 | 3 | .429 | 2 | 24 | 6 | .250 | 45 | 42 | 15 | 32.5 | .609 |
| Anibal Sanchez | CAL | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 7 | 5 | .714 | 9 | 8 | 3 | 44.0 | .558 |
| Jonathan Sanchez* | HOU | mr | 25 | 4 | 3 | .750 | 1 | .250 | 3 | 34 | 11 | .324 | 44 | 44 | 26 | 20.0 | .585 |
| Ervin Santana | HOU | sp | 25 | 0 | 0 | .000 | 0 | .000 | 1 | 9 | 3 | .333 | 35 | 11 | 2 | 68.9 | .621 |
| Johan Santana* | KCA | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 96.4 | .659 |
| Joe Saunders* | PHI | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 17 | 1 | 1 | 89.6 | .633 |
| Curt Schilling | BAL | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 23 | 0 | 0 | 92.3 | .667 |
| Scott Schoeneweis* | BOS | mr | 34 | 0 | 0 | .000 | 0 | .000 | 0 | 1 | 0 | .000 | 4 | 4 | 1 | 21.0 | .655 |
| Chris Schroder | CLE | mr | 29 | 8 | 4 | .500 | 3 | .375 | 5 | 18 | 7 | .389 | 33 | 33 | 15 | 21.6 | .619 |
| Rudy Seanez | BOS | mr | 39 | 9 | 7 | .778 | 1 | .111 | 4 | 24 | 8 | .333 | 37 | 37 | 23 | 26.0 | .595 |
| Bobby Seay* | DET | mr | 30 | 5 | 2 | .400 | 3 | .600 | 14 | 43 | 11 | .256 | 57 | 57 | 14 | 12.6 | .629 |
| Ben Sheets | KCA | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 20 | 0 | 0 | 98.2 | .643 |
| George Sherrill* | CHI | mr | 31 | 9 | 3 | .333 | 6 | .667 | 12 | 29 | 9 | .310 | 48 | 48 | 14 | 13.6 | .610 |
| James Shields | CWS | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 97.9 | .671 |
| Scot Shields | PHI | mr | 32 | 12 | 7 | .583 | 4 | .333 | 20 | 38 | 10 | .263 | 66 | 66 | 22 | 17.4 | .599 |
| Brian Shouse* | DET | mr | 39 | 5 | 1 | .200 | 3 | .600 | 8 | 26 | 8 | .308 | 40 | 40 | 10 | 13.9 | .629 |
| Carlos Silva | BOS | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 93.4 | .655 |
| Carlos Silva | MIN | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 88.0 | .677 |
| Carlos Silva |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 91.2 | .664 |
| Doug Slaten* | NYM | mr | 28 | 1 | 0 | .000 | 1 | 1.000 | 4 | 14 | 8 | .571 | 24 | 24 | 7 | 15.8 | .578 |
| Kevin Slowey | BOS | sp | 24 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 12 | 0 | 0 | 88.8 | .661 |
| Joe Smith | CIN | mr | 24 | 2 | 0 | .000 | 2 | 1.000 | 7 | 32 | 11 | .344 | 43 | 43 | 5 | 18.0 | .585 |
| John Smoltz | STL | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 2 | 1 | 98.4 | .650 |
| Ian Snell | MIL | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 19 | 7 | 1 | 69.9 | .622 |
| Ian Snell | HOU | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 100.4 | .626 |
| Ian Snell |   | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 2 | .667 | 35 | 7 | 1 | 83.9 | .625 |
| Kyle Snyder | BOS | mr | 30 | 2 | 1 | .500 | 1 | .500 | 9 | 16 | 5 | .313 | 49 | 49 | 12 | 18.7 | .580 |
| Andy Sonnanstine | CIN | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 22 | 0 | 0 | 86.0 | .664 |
| Joakim Soria | KCA | cl | 24 | 40 | 36 | .900 | 4 | .100 | 0 | 29 | 6 | .207 | 55 | 55 | 47 | 16.9 | .646 |
| Rafael Soriano | KCA | mr | 28 | 4 | 2 | .500 | 0 | .000 | 11 | 31 | 6 | .194 | 52 | 52 | 19 | 16.0 | .662 |
| Jorge Sosa | SFG | mr | 31 | 1 | 1 | 1.000 | 0 | .000 | 2 | 15 | 2 | .133 | 25 | 21 | 8 | 33.1 | .579 |
| Jeremy Sowers* | NYM | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 80.4 | .626 |
| Jeremy Sowers* | STL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 2 | 0 | 0 | 47.5 | .737 |
| Jeremy Sowers* |   | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 76.3 | .635 |
| Justin Speier | SFG | mr | 34 | 3 | 2 | .667 | 1 | .333 | 7 | 6 | 1 | .167 | 38 | 38 | 19 | 18.9 | .656 |
| Russ Springer | BAL | mr | 39 | 7 | 2 | .286 | 3 | .429 | 2 | 24 | 13 | .542 | 38 | 38 | 19 | 21.2 | .627 |
| Huston Street | CWS | cl | 24 | 28 | 23 | .821 | 5 | .179 | 0 | 24 | 6 | .250 | 45 | 45 | 38 | 15.8 | .661 |
| Jeff Suppan | SFG | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 89.9 | .624 |
| Brian Tallet* | SFG | mr | 30 | 4 | 3 | .750 | 1 | .250 | 5 | 26 | 6 | .231 | 48 | 48 | 18 | 21.0 | .620 |
| Taylor Tankersley* | MIL | mr | 25 | 3 | 2 | .667 | 1 | .333 | 4 | 30 | 16 | .533 | 43 | 43 | 10 | 16.6 | .574 |
| Jack Taschner* | LAD | mr | 30 | 7 | 3 | .429 | 3 | .429 | 1 | 26 | 11 | .423 | 48 | 47 | 23 | 17.6 | .571 |
| Julian Tavarez | MIL | sp | 35 | 1 | 0 | .000 | 1 | 1.000 | 0 | 6 | 4 | .667 | 16 | 12 | 9 | 40.4 | .645 |
| Brad Thompson | LAD | mr | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 3 | 2 | 1 | 54.3 | .620 |
| Matt Thornton* | CHI | mr | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 2 | 1 | .500 | 2 | 2 | 0 | 39.5 | .646 |
| Mike Timlin | DET | mr | 42 | 7 | 4 | .571 | 3 | .429 | 9 | 18 | 7 | .389 | 44 | 44 | 15 | 16.3 | .645 |
| Josh Towers | CIN | sp | 31 | 7 | 4 | .571 | 3 | .429 | 4 | 43 | 14 | .326 | 60 | 58 | 22 | 21.9 | .697 |
| Steve Trachsel | MIL | sp | 37 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 1 | .333 | 13 | 3 | 1 | 68.2 | .589 |
| Derrick Turnbow | NYA | mr | 30 | 2 | 2 | 1.000 | 0 | .000 | 3 | 11 | 2 | .182 | 34 | 34 | 17 | 22.1 | .571 |
| Jose Valverde | CWS | cl | 28 | 16 | 12 | .750 | 4 | .250 | 10 | 23 | 3 | .130 | 54 | 54 | 29 | 17.7 | .601 |
| Rick VandenHurk | HOU | sp | 23 | 4 | 2 | .500 | 1 | .250 | 7 | 38 | 15 | .395 | 57 | 54 | 15 | 25.8 | .592 |
| Claudio Vargas | BAL | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 21 | 1 | 0 | 97.7 | .601 |
| Javier Vazquez | CWS | sp | 31 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 100.8 | .650 |
| Justin Verlander | STL | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 33 | 0 | 0 | 101.2 | .627 |
| Carlos Villanueva | STL | mr | 24 | 3 | 1 | .333 | 2 | .667 | 7 | 25 | 10 | .400 | 53 | 48 | 14 | 33.0 | .594 |
| Oscar Villarreal | PIT | mr | 26 | 8 | 3 | .375 | 5 | .625 | 5 | 45 | 14 | .311 | 57 | 57 | 16 | 21.4 | .626 |
| Ron Villone* | KCA | mr | 38 | 5 | 3 | .600 | 2 | .400 | 3 | 9 | 1 | .111 | 31 | 31 | 16 | 20.1 | .608 |
| Luis Vizcaino | MIN | mr | 33 | 5 | 2 | .400 | 3 | .600 | 13 | 28 | 5 | .179 | 57 | 57 | 18 | 17.7 | .592 |
| Billy Wagner* | NYA | cl | 36 | 7 | 2 | .286 | 4 | .571 | 7 | 30 | 15 | .500 | 56 | 56 | 16 | 16.4 | .657 |
| Adam Wainwright | PIT | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 96.5 | .627 |
| Tim Wakefield | CLE | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 16 | 0 | 0 | 94.1 | .617 |
| Tim Wakefield | MIN | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 13 | 0 | 0 | 94.8 | .628 |
| Tim Wakefield |   | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 94.4 | .622 |
| Jamie Walker* | BOS | mr | 36 | 2 | 0 | .000 | 2 | 1.000 | 13 | 33 | 5 | .152 | 53 | 53 | 14 | 16.2 | .641 |
| Chien-Ming Wang | CLE | sp | 28 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 98.3 | .627 |
| Jarrod Washburn* | BOS | sp | 33 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 29 | 0 | 0 | 100.8 | .631 |
| David Weathers | CIN | cl | 38 | 24 | 19 | .792 | 5 | .208 | 7 | 33 | 7 | .212 | 69 | 69 | 45 | 15.9 | .610 |
| Jered Weaver | PHI | sp | 25 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 26 | 0 | 0 | 94.5 | .641 |
| Brandon Webb | SFG | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 18 | 0 | 0 | 102.4 | .644 |
| Brandon Webb | WAS | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 14 | 0 | 0 | 107.8 | .620 |
| Brandon Webb |   | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 104.8 | .633 |
| Todd Wellemeyer | BOS | mr | 29 | 2 | 1 | .500 | 1 | .500 | 5 | 40 | 14 | .350 | 50 | 50 | 16 | 26.0 | .590 |
| Kip Wells | HOU | sp | 31 | 1 | 1 | 1.000 | 0 | .000 | 0 | 1 | 0 | .000 | 18 | 5 | 2 | 72.7 | .596 |
| Jake Westbrook | MIN | sp | 30 | 0 | 0 | .000 | 0 | .000 | 1 | 3 | 1 | .333 | 27 | 5 | 3 | 75.6 | .619 |
| Dan Wheeler | CIN | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 6 | 30 | 7 | .233 | 60 | 60 | 11 | 18.3 | .646 |
| Bob Wickman | SFG | cl | 39 | 2 | 2 | 1.000 | 0 | .000 | 0 | 12 | 2 | .167 | 19 | 19 | 9 | 24.0 | .610 |
| Woody Williams | BOS | sp | 41 | 0 | 0 | .000 | 0 | .000 | 0 | 5 | 5 | 1.000 | 16 | 11 | 3 | 59.3 | .602 |
| Dontrelle Willis* | CLE | sp | 26 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 34 | 0 | 0 | 92.9 | .604 |
| C.J. Wilson* | CIN | mr | 27 | 9 | 2 | .222 | 2 | .222 | 11 | 24 | 8 | .333 | 61 | 61 | 18 | 17.8 | .579 |
| Matt Wise | MIL | mr | 32 | 3 | 0 | .000 | 3 | 1.000 | 2 | 9 | 4 | .444 | 20 | 20 | 7 | 20.2 | .609 |
| Randy Wolf* | HOU | sp | 31 | 1 | 1 | 1.000 | 0 | .000 | 1 | 19 | 5 | .263 | 42 | 33 | 10 | 39.2 | .631 |
| Brian Wolfe | DET | mr | 27 | 5 | 2 | .400 | 3 | .600 | 5 | 11 | 3 | .273 | 26 | 26 | 8 | 12.5 | .643 |
| Kerry Wood | BOS | mr | 31 | 7 | 6 | .857 | 0 | .000 | 0 | 10 | 1 | .100 | 22 | 22 | 17 | 16.9 | .528 |
| Jamey Wright | MIL | mr | 33 | 6 | 1 | .167 | 4 | .667 | 7 | 37 | 14 | .378 | 47 | 47 | 15 | 23.7 | .579 |
| Michael Wuertz | LAD | mr | 29 | 8 | 7 | .875 | 1 | .125 | 9 | 45 | 18 | .400 | 65 | 65 | 22 | 19.0 | .614 |
| Tyler Yates | NYM | mr | 30 | 1 | 1 | 1.000 | 0 | .000 | 3 | 24 | 4 | .167 | 28 | 28 | 8 | 21.0 | .583 |
| Chris Young | CWS | sp | 29 | 0 | 0 | .000 | 0 | .000 | 0 | 3 | 0 | .000 | 29 | 1 | 1 | 96.7 | .581 |
| Carlos Zambrano | CAL | sp | 27 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 31 | 0 | 0 | 112.2 | .586 |
| Barry Zito* | PIT | sp | 30 | 0 | 0 | .000 | 0 | .000 | 0 | 0 | 0 | .000 | 32 | 0 | 0 | 95.3 | .623 |
| Joel Zumaya | DET | mr | 23 | 3 | 1 | .333 | 1 | .333 | 8 | 21 | 4 | .190 | 30 | 30 | 5 | 18.5 | .596 |